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10 Best CBD Oils on the Market Right Now

Lists like this collect and curate the best of the best CBD oil with an objective lens.

Lists like this collect and curate the best of the best CBD oil with an objective lens. BSIP/Universal Images Group via Getty Images

Trying to find the best CBD oil and aren’t sure where to look? Well, you’ve found the right place to get started.

After the legalization of hemp in all 50 states, there was a massive boom in the CBD oil market. It went from a couple dozen companies to now hundreds (possibly even thousands) of CBD brands. It’s become almost impossible to keep track of them, as more seem to pop up every other week.

This has created a dilemma for consumers. There is an over-saturation of choices at the moment, and not all of them are worthwhile. In fact, there are more inferior products out there than high-quality ones.

So, how does one weed through all the junk to find the gems?

The average consumer usually relies on reviews and word of mouth. This can be tricky, though. Information on the internet is often deceptive, and it’s hard to tell who is being honest and who is just part of a scheme to sell you something. That’s why lists like this one have become popular, as they collect and curate the best of the best with an objective lens.

We’ve put in months of research to create this list. Our hope is that interested consumers can use the list to make an informed decision before making their purchases.

Before we reveal the cream of the CBD crop, let’s go over the criteria by which we judged and ranked each entry.

CBD Oil Score Criteria

There are a number of factors to consider when determining the quality of CBD oil. So many, in fact, that it would be a herculean task to take them all into account. All we could do was narrow them down to the essentials.

Here are the main aspects we focused on to create our rating system:

Ingredient Quality

The ingredients used to create the oil, where the ingredients were sourced, how fresh the batches were before being sent out and the quality-control measures enacted to ensure purity.

Taste

The flavor of the product, as well as any lingering aftertaste.

Value

The cost-effectiveness of the product, with its quality weighed against the quantity and price.

Transparency

The availability of information about the product, its means of production, third-party test results and sales/refund policies as provided by the brand.

User Reputation

The reputability of the brand, based on user reviews and comments from across the internet.

Customer Service

The availability, responsiveness, clarity and helpfulness of the brand’s customer service team.

Website Experience

The ease of use of their website while browsing, selecting products and placing orders.

Overall

Our final verdict on the product as a whole, considering all of the elements above.

10 Best CBD Oils

1. Verma Farms

2 verma farms

Verma Farms. Courtesy of Verma Farms 2 verma farms

Overview

Price Range: $59.99
Available Flavors: Mint, Natural, Lemon Lime, Strawberry, Watermelon, Mango, Pineapple, Peach
CBD Per Serving: 16.67 mg
CBD Per Bottle: 500 mg
Type of CBD: Broad-Spectrum
Lab Results: Available upon request
Refund Policy: 30-day return guarantee

Description

Verma Farms soars high in our rankings because of their unique approach to CBD. Their Hawaiian-inspired line of products is simply delightful. We especially like their assortment of gummies and dried fruits, but that’s a different list for another day. Their award-winning oils are equally worth checking out.

Their oils come in enough flavors to fill a luau table. If we had to choose one from the bunch, it’d probably have to be pineapple. Nothing says “tropical” quite like its delicately balanced sweet-yet-tart taste. The mango and peach flavors are no slouches either, though. We’d recommend getting the Fruit Pack if possible for a real party.

Score Card

Ingredient Quality: 10 out of 10
Taste: 10 out of 10
Value: 10 out of 10
Transparency: 10 out of 10
User Reputation: 10 out of 10
Customer Service: 10 out of 10
Website Experience : 10 out of 10
Overall: 10 out of 10

Penguin CBD

Penguin CBD. Courtesy of Penguin CBD

2. Penguin CBD

Overview

Price Range: $45 to $105
Available Flavors: Natural, Mint, Citrus, Strawberry, Cookies & Cream
CBD Per Serving: 8.3 mg, 20 mg, 33.3 mg
CBD Per Bottle: 250 mg, 600 mg, 1000 mg
Type of CBD: Broad-Spectrum
Lab Results: Available on website
Refund Policy: 30-day return guarantee

Description

Penguin slides right into second place on our list. It earns this spot by offering one of the most well-rounded CBD oils we’ve tried in a long time. Their broad-spectrum formula is not only potent and great tasting (we’re particularly fond of the mint flavor), it’s reasonably priced as well.

All of Penguin’s products are sourced from their farm in Oregon, where their hemp is grown organically without the use of pesticides, solvents or chemical fertilizers. It then goes through a CO2 extraction process, which ensures that the final product preserves all of the natural terpenes without any of the THC.

There is a good reason that this brand has been named the #1 best CBD oil by the likes of Merry Jane; from seed to sale, Penguin is the definition of CBD excellence.

Score Card

Ingredient Quality: 10 out of 10
Taste: 10 out of 10
Value: 10 out of 10
Transparency: 10 out of 10
User Reputation: 10 out of 10
Customer Service: 10 out of 10
Website Experience : 10 out of 10
Overall: 10 out of 10

3. Green Roads

3 green roads

Green Roads. Courtesy of Green Roads 3 green roads

Overview

Price Range: $44.99 to $149.99
Available Flavors: Unflavored, Apple Kiwi Bliss, Mint Breeze
CBD Per Serving: 10 mg, 25 mg, 50 mg
CBD Per Bottle: 300 mg, 750 mg, 1500 mg
Type of CBD: Broad-Spectrum and Full-Spectrum
Lab Results: Available on website
Refund Policy: 30-day return guarantee

Description

The ethos behind Green Roads has made it one of our perennial favorites. Recipient of the “Best CBD Product” award at the 2018 Cannabis Business Awards, this brand is dedicated to educating the public about CBD and delivering the purest products around. They are also strong advocates for accessibility and bringing CBD to those who need it most, with discounts for military veterans and first responders.

Their main line of CBD oil is an unflavored formula that comes in three main potencies: 300 mg, 750 mg and 1500 mg. You can either get the classic bottle with a dropper, or you could try their pre-measured Daily Doses. They also have delicious Apple Kiwi Bliss and Mint Breeze flavors, if you’re not a fan of the plain stuff.

Score Card

Ingredient Quality: 9.5 out of 10
Taste: 9.5 out of 10
Value: 10 out of 10
Transparency: 10 out of 10
User Reputation: 9.5 out of 10
Customer Service: 9 out of 10
Website Experience : 9 out of 10
Overall: 9.5 out of 10

4. PureKana

4 purekana

PureKana. Courtesy of PureKana 4 purekana

Overview

Price Range: $54 to $390
Available Flavors: Natural, Mint, Vanilla
CBD Per Serving: 7.5 mg, 15 mg, 25 mg, 41.6 mg, 83.3 mg
CBD Per Bottle: 300 mg, 600 mg, 1000 mg, 2500 mg, 5000 mg
Type of CBD: Full-Spectrum
Lab Results: Available on website
Refund Policy: 30-day return guarantee

Description

PureKana is a brand you’ll often see near the top of lists like this, and for good reason. Their CBD hemp oil is some of the highest quality on the market. They utilize a full-spectrum extraction process, which means that all of the natural compounds found in hemp are preserved.

Currently, they offer their oil in natural, mint and vanilla flavor options. The subtle and smooth taste of vanilla is our personal recommendation. Their oil also comes in a range of dosage strengths, with the strongest being a whopping 83.3 mg per serving.

Score Card

Ingredient Quality: 10 out of 10
Taste: 9.5 out of 10
Value: 9.5 out of 10
Transparency: 9.5 out of 10
User Reputation: 9.5 out of 10
Customer Service: 9 out of 10
Website Experience : 9.5 out of 10
Overall: 9.5 out of 10

5. 4Corners Cannabis

5 4corners cannabis

4Corners Cannabis. Courtesy of 4Corners Cannabis 5 4corners cannabis

Overview

Price Range: $25.49 to $297.49
Available Flavors: Earthy Avocado, Coconut Citrus, Simply Cinnamon, Sweet Citrus, Choco Mint
CBD Per Serving: 0 mg, 16.7 mg, 33.3 mg, 66.7 mg
CBD Per Bottle: 100 mg, 200 mg, 500 mg, 1000 mg, 2000 mg
Type of CBD: Broad-Spectrum and Full-Spectrum
Lab Results: Available on website
Refund Policy: 30-day return guarantee

Description

The CBD world has its own little niches. Created by the Jasiewicz brothers, 4Corners Cannabis is a Colorado-based brand that focuses on an underlooked aspect of CBD tinctures: carrier oils. These are the solvents that help “carry” the cannabinoids and aid in their absorption into your system.

Some of the carrier oils that 4Corners offers with their tinctures include avocado oil, coconut-based MCT oil, and vegetable glycerin. Each one has their own upsides and drawbacks. For instance, vegetable glycerin can be vaped and is generally safe for people with allergies, although it’s not quite as high in bioavailability as the other two.

Score Card

Ingredient Quality: 9 out of 10
Taste: 9 out of 10
Value: 9.5 out of 10
Transparency: 9 out of 10
User Reputation: 9 out of 10
Customer Service: 9 out of 10
Website Experience : 8.5 out of 10
Overall: 9 out of 10

6. Medterra

6 medterra

Medterra. Courtesy of Medterra 6 medterra

Overview

Price Range: $34.99 to $132.99
Available Flavors: Unflavored, Strawberry Mint, Citrus
CBD Per Serving: 16 mg, 33 mg, 100 mg
CBD Per Bottle: 500 mg, 1000 mg, 3000 mg
Type of CBD: CBD Isolate and Broad-Spectrum
Lab Results: Available on website
Refund Policy: 30-day return guarantee

Description

Medterra is one of the biggest and best CBD oil brands on the market right now. That’s because their products are made by a passionate team of experts, including a medical advisory board staffed with some of the best physicians in the country. So you can rest assured that they are formulated with the utmost care and concern for improving your well-being.

Their signature CBD oil tincture is a flavorless CBD isolate extract that comes in strengths of 500 mg, 1000 mg and 3000 mg. They also have an Immune Boost variant with vitamins and other natural ingredients. If you want more cannabinoids than just CBD, you should definitely check out their broad-spectrum blends, which also come in a few flavor options.

Score Card

Ingredient Quality: 9 out of 10
Taste: 10 out of 10
Value: 9 out of 10
Transparency: 9 out of 10
User Reputation: 9 out of 10
Customer Service: 8 out of 10
Website Experience : 9 out of 10
Overall: 9 out of 10

7. Mission Farms CBD

7 mission farms

Mission Farms CBD. Courtesy of Mission Farms CBD 7 mission farms

Overview

Price Range: $29 to $99
Available Flavors: Vanilla Mint, Orange Lavender, Citrus Cream
CBD Per Serving: 25 mg
CBD Per Bottle: 250 mg, 1000 mg
Type of CBD: Broad-Spectrum
Lab Results: Available on website
Refund Policy: 30-day return guarantee

Description

Mission Farms is a newcomer to the arena of CBD oil. However, they’ve already made quite an impression. They grow their own hemp on their Colorado farms and oversee every step of the CBD extraction process to ensure a high level of quality.

They make four types of CBD oil: Pure, Rest, Relieve and Relax. As you can guess, each one has a specific blend of ingredients to help you improve your mood, get better sleep, relieve chronic pain and calm your nerves. They are available in trial size (250 mg) and full size (1000 mg) bottles.

Score Card

Ingredient Quality: 9 out of 10
Taste: 8.5 out of 10
Value: 8.5 out of 10
Transparency: 8.5 out of 10
User Reputation: 8.5 out of 10
Customer Service: 8 out of 10
Website Experience : 8.5 out of 10
Overall: 8.5 out of 10

8. Premium Jane

8 premium jane

Premium Jane. Courtesy of Premium Jane 8 premium jane

Overview

Price Range: $48 to $124
Available Flavors: Natural, Citrus, Mint
CBD Per Serving: 7.5 mg, 15 mg, 25 mg
CBD Per Bottle: 300 mg, 600 mg, 1000 mg
Type of CBD: Full-Spectrum
Lab Results: Available on website
Refund Policy: 30-day return guarantee

Description

Premium Jane is another brand that’s relatively new; however, they’ve quickly proven to be a worthy contender for a spot in our top 10. Their quality assurance is second to none, as all of their products are thoroughly tested by third-party labs. The result is some of the cleanest tasting CBD oil we’ve sampled.

Aside from a natural unflavored option, their oil comes in pleasing citrus and mint flavors. We also really dig the packaging. It’s a small thing, but Premium Jane makes CBD look classy in a way that we appreciate. It does a lot to help remove the stigma surrounding it.

Score Card

Ingredient Quality: 10 out of 10
Taste: 8 out of 10
Value: 8.5 out of 10
Transparency: 8.5 out of 10
User Reputation: 8 out of 10
Customer Service: 8 out of 10
Website Experience : 8.5 out of 10
Overall: 8.5 out of 10

9. Hemp Bombs

9 hemp bombs

Hemp Bombs. Courtesy of Hemp Bombs 9 hemp bombs

Overview

Price Range: $24.99 to $299.99
Available Flavors: Unflavored, Acai Berry, Orange Creamsicle, Peppermint, Watermelon
CBD Per Serving: 2.08 mg, 5 mg, 10 mg, 16.6 mg, 33.3 mg, 66.6 mg
CBD Per Bottle: 125 mg, 300 mg, 600 mg, 1000 mg, 2000 mg, 4000 mg
Type of CBD: Broad-Spectrum
Lab Results: Available on website
Refund Policy: No refunds

Description

Speaking of CBD oils with great flavors, Hemp Bombs has a veritable smorgasbord of options. All of them taste amazing, but if pressed, we’d have to go with the orange creamsicle. Hemp Bombs is also sensibly priced and constantly updates their sizable database of third-party lab results.

The only drawback to Hemp Bombs is that they don’t offer refunds after a purchase has been made. However, if you contact customer service, they will consider giving you discounts on future purchases. This is a minor strike against an otherwise excellent brand.

Score Card

Ingredient Quality: 8 out of 10
Taste: 9 out of 10
Value: 8 out of 10
Transparency: 9 out of 10
User Reputation: 8 out of 10
Customer Service: 7 out of 10
Website Experience : 7 out of 10
Overall: 8 out of 10

10. Lazarus Naturals

10 Lazarus Naturals

Lazarus Naturals. Courtesy of Lazarus Naturals 10 Lazarus Naturals

Overview

Price Range: $32 to $200
Available Flavors: Chocolate Mint, French Vanilla Mocha, Blood Orange, Tropical Breeze, Wintermint, Unflavored
CBD Per Serving: 50 mg
CBD Per Bottle: 750 mg, 3000 mg, 6000 mg
Type of CBD: Full-Spectrum, CBD Isolate
Lab Results: Available on website
Refund Policy: 30-day return guarantee

Description

If you’re in need of a high-potency CBD oil, then Lazarus Naturals has you covered. All of their tinctures pack an impressive 50 mg of CBD per serving. Not only are they strong, even for experienced CBD users, but they’re delicious and go down smoothly as well.

Lazarus Naturals was founded in 2014, so it’s one of the oldest and most reliable CBD brands. Its core philosophy is providing the public with high-quality CBD oil regardless of their financial situation. They provide assistance programs for veterans, people with long-term disabilities and low-income individuals.

Score Card

Ingredient Quality: 8 out of 10
Taste: 9 out of 10
Value: 8.5 out of 10
Transparency: 8 out of 10
User Reputation: 8 out of 10
Customer Service: 7.5 out of 10
Website Experience : 7 out of 10
Overall: 8 out of 10

Frequently Asked Questions About CBD

What Is CBD?

CBD is short for cannabidiol. It’s a compound found within the Cannabis sativa plant, and is especially abundant in the strain known as hemp.

There has often been confusion between marijuana and hemp. The key difference is that marijuana is a plant primarily used as a recreational and medical drug, while hemp is a more fibrous and versatile material that can be used to create fabrics, construction materials, biofuels and dietary supplements.

How Does CBD Work?

Inside the human body there is a network of receptors known as the endocannabinoid system (ECS). This system sends out signals and helps regulate various other systems of the body, such as our nervous system and immune system. It is also tied to virtually every organ we have.

Our bodies naturally create neurotransmitters known as endocannabinoids, to be used by the ECS for its numerous regulatory functions. However, sometimes people don’t produce enough endocannabinoids. That’s where cannabinoids such as tetrahydrocannabinol (THC) and cannabidiol (CBD) step in. They serve almost the same function as their endocannabinoid relatives and keep the system running in top shape.

CBD promotes homeostasis (balance) within the human body. That means it is totally natural for humans to consume it, as we are built for it.

Is CBD Legal?

Currently, CBD is legal in all 50 states. However, some states have narrower laws and regulations than others. This is something that should be thoroughly researched before buying any CBD products.

What Are the Health Benefits of CBD?

In recent years, studies have suggested that CBD can be used to treat and alleviate all sorts of conditions and symptoms. However, the research is still ongoing and should not be treated as total fact yet. Given that CBD was only recently legalized, it is too early to tell anything for certain.

It is typically advised that you speak to your doctor about CBD before trying it. That way you can come up with a plan that suits your specific needs. Certain conditions may require higher dosage strengths than others.

Does CBD Make You High?

No, CBD does not make you high. This is a common misconception due to its similarities with THC, another compound found in cannabis. The difference is that THC is psychoactive and can alter your mental state.

CBD is the exact opposite of that. It actually combats the effects of THC by promoting greater mental clarity and focus.

It should be noted, however, that some CBD oils contain trace amounts of THC. That’s due to the fact that THC is still present in hemp, though the amount is often negligible (0.3% or less is the standard). But even this is too insignificant to cause any sort of high.

See the section below for further details, including which types of CBD contain absolutely zero THC.

What Are the Different Types of CBD?

There are currently three types of CBD that are common on the market:

CBD Isolate: This is the purest form of CBD available. It has been refined to remove all hemp compounds except for CBD. That means it has absolutely zero THC. However, this comes at the cost of numerous terpenes and other nutrients, which have their own health benefits.

Full-Spectrum: This type of CBD is on the opposite end of the spectrum from CBD isolates. It contains all of the natural compounds that you will find in hemp, and even small amounts of THC. Some prefer it because it produces an “entourage effect,” in which the compounds interact with and strengthen each other.

Broad-Spectrum: This form is considered a balance between the previous two. It retains both the CBD and all of the beneficial compounds, but it eliminates the THC completely. This extraction process still allows the entourage effect to happen.

How Do I Use CBD Oil?

CBD is a versatile supplement, so there are a number of ways to consume it. Some people mix it right into their food or drink. That is usually enough to cover up the natural “earthy” flavor of hemp, which many people dislike.

However, the most effective method is to apply the full dose directly under your tongue and hold it for 60-90 seconds before swallowing. This maximizes bioavailability and makes sure that it circulates properly through your body’s systems.

10 Best CBD Oils on the Market Right Now

When you aren’t using CBD, you should store it in a place with minimal heat and moisture, such as a pantry or cabinet. Some prefer to keep it in the refrigerator, although that might thicken the oil over time. If that happens, all you have to do is run the bottle under warm water and then shake it up to restore it to the original consistency.

After the legalization of hemp in all 50 states, there was a massive boom in the CBD oil market. That’s why lists like this one have become popular, as they collect and curate the best of the best CBD oil with an objective lens.

Does CBD oil work for chronic pain management?

Many people use cannabidiol (CBD) to relieve pain. Understanding CBD can help overcome the stigma associated with it.

CBD oil is derived from the cannabis plant. People report using this oil for relief from pain, anxiety, depression, and sleep disorders.

There is limited evidence from human studies to support the benefits of CBD oil, due to restrictions on the use of and research on cannabis. As cannabis is becoming legalized in various regions, research is gaining momentum and shows some promising results.

In this article, we look at how CBD oil works and how people use it to relieve chronic pain.

A small bottle of CBD oil against a green background with a dropper held above it

Share on Pinterest Eddie Pearson/Stocksy United

CBD is one of more than 100 compounds found in cannabis, called cannabinoids. Many plants contain cannabinoids, but people most commonly link these compounds to cannabis.

Unlike other cannabinoids — such as tetrahydrocannabinol (THC) — CBD does not produce a euphoric “high.” This is because CBD does not affect the same receptors as THC.

The human body has an endocannabinoid system (ECS) that receives and translates signals from cannabinoids. It produces some cannabinoids of its own, which are called endocannabinoids. The ECS helps regulate functions such as sleep, immune-system responses, and pain.

When THC enters the body, it produces a “high” feeling by affecting the brain’s endocannabinoid receptors. This activates the brain’s reward system, producing pleasure chemicals such as dopamine.

Does CBD make you high?

CBD is an entirely different compound from THC, and its effects are very complex. It does not produce a “high” and does not impair a person’s functioning, but it influences the body to use its own endocannabinoids more effectively.

According to a 2015 study published in Neurotherapeutics, CBD influences many other receptor systems in our body and will influence the ECS in combination with other cannabinoids.

For example, CBD can increase the body’s levels of anandamide, a compound associated with regulating pain, which can reduce pain perception and improve mood.

Cannabidiol may also limit inflammation in the brain and nervous system, which may benefit people experiencing pain, insomnia, and certain immune system responses.

For more information and resources on CBD and CBD products, please visit our dedicated hub.

Different varieties of cannabis plants — such as hemp and marijuana — contain different levels of chemical compounds.

How people breed the plant affects the CBD levels. Most CBD oil comes from industrial hemp, which usually has a higher CBD content than marijuana.

Makers of CBD oil use different methods to extract the compound. The extract is then added to a carrier oil and called CBD oil.

CBD oil comes in many different strengths, and people use it in various ways. It is best to discuss CBD oil with a doctor before using it.

According to the National Centers for Complementary and Integrative Health (NCCIH), some evidence suggests that cannabis or CBD could have modest benefits for chronic pain.

While CBD is a promising option for pain relief, research has not yet proven it safe and effective, and the Food and Drug Administration (FDA) have not approved CBD for treating pain.

A 2020 review reports that CBD could have benefits for relieving chronic pain, improving sleep, and reducing inflammation, but that these effects are condition-specific.

More evidence is needed to determine the therapeutic potential of CBD and to determine safe and effective dosages for pain.

Based on the current research, here are some possible benefits of CBD oil:

Neuropathic pain

Neuropathic pain is pain caused by damage to the nerves. This type of pain is common in diseases such as multiple sclerosis, injuries such as herniated discs, and infections such as shingles.

A 2017 review found that CBD helped with chronic neuropathy pain in humans. The researchers looked at 11 randomized controlled trials with 1,219 patients.

However, a 2018 Cochrane review concluded that the potential benefits of cannabis-based medicine might be outweighed by its potential harms.

This research looked into the effects of cannabis-derived medicines, including CBD, for chronic neuropathic pain. It looked at 16 studies and 1,750 participants.

More research is needed to understand the role of CBD in chronic neuropathic pain management, including the risks, benefits, and ideal dosages.

Arthritis pain

A 2016 study in the European Journal of Pain used an animal model to see if CBD could help people with arthritis manage their pain. Researchers applied a topical gel containing CBD to rats with arthritis for 4 days.

Their researchers noted a significant drop in inflammation and signs of pain, without additional side effects.

People using CBD oil for arthritis may find relief from their pain, but more human studies need to be done to confirm these findings.

Multiple sclerosis

Multiple sclerosis (MS) is an autoimmune condition that affects the entire body through the nerves and brain.

Muscle spasms are one of the most common symptoms of MS. These spasms can be so strong they cause constant pain in some people.

One report found that short-term use of CBD oil could reduce the levels of muscle spasms a person feels. The results are modest, but many people reported a reduction in symptoms. More studies on humans are needed to verify these results.

Chronic pain

The same report studied CBD use for general chronic pain. Researchers compiled the results of multiple systematic reviews covering dozens of trials and studies. Their research concluded that there is substantial evidence that cannabis is an effective treatment for chronic pain in adults.

A separate study in the Journal of Experimental Medicine supports these results. This research suggests that using CBD can reduce pain and inflammation.

The researchers also found that subjects were not likely to build up a tolerance to the effects of CBD, so they would not need to increase their dose over time.

They noted that cannabinoids, such as CBD, could offer helpful new treatments for people with chronic pain.

CBD currently has a range of applications and promising possibilities.

  • helping people quit smoking
  • managing drug withdrawal
  • treating seizures and epilepsy
  • treating anxiety
  • reducing some effects of Alzheimer’s disease
  • reducing antipsychotic effects for people with schizophrenia
  • potentially combating type 1 diabetes and cancer in the future

Although more research is required to confirm the benefits of CBD oil, it is shaping up as a potentially promising and versatile treatment.

The Food and Drug Administration (FDA) have approved one form of CBD, called Epidiolex, to treat two rare forms of epilepsy and to treat seizures caused by a rare condition called tuberous sclerosis complex.

More generally, marijuana-derived CBD products are not yet legal at the federal level but are legal under the laws of some states.

People should check their state’s laws and those of any place they intend to travel. They must keep in mind that the FDA do not approve or regulate nonprescription CBD products. As a result, labeling may be inaccurate.

The FDA does not regulate CBD for most conditions. As a result, dosages are currently open to interpretation, and people should treat them with caution.

Anyone who wishes to use CBD should first speak to a doctor about whether it will be beneficial or safe, and how much to take.

The FDA has approved a purified form of CBD for some types of epilepsy, with the brand name Epidiolex. People using this medication should follow the doctor’s advice about doses.

Most people tolerate CBD oil well, but there are some possible side effects.

According to a 2017 review in Cannabis and Cannabinoid Research, the most common side effects include:

  • fatigue
  • diarrhea
  • changes in appetite
  • weight gain or weight loss

In addition, using CBD oil with other medications may make those medications more or less effective.

The review also notes that scientists have yet to study some aspects of CBD, such as its long-term effects on hormones. Further long-term studies will be helpful in determining any side effects CBD has on the body over time.

Consult a doctor before using CBD, as it may interact with certain over-the-counter dietary supplements and medicines, as well as some prescription medications — especially those that warn against consuming grapefruit .

CBD might also interfere with an enzyme called cytochrome P450 complex. This disruption could affect the liver’s ability to break down toxins, increasing the risk of liver toxicity.

The patient information leaflet for Epidiolex cautions that there is a risk of liver damage, lethargy, and possibly depression and thoughts of suicide, but these potential side effects are true of other treatments for epilepsy, too.

One study in Frontiers in Pharmacology, suggested cannabinoids’ anti-inflammatory effect may reduce inflammation too much. A large reduction in inflammation could diminish the lungs’ defense system, increasing the risk of infection.

Almost all research on CBD oil and pain comes from adult trials. Experts do not recommend CBD oil for use in children, as there is little research on the effects of CBD oil on a child’s developing brain.

However, people may use Epidiolex for children ages 2 and above who have rare forms of epilepsy.

People should not use CBD oil when pregnant or breastfeeding.

People should use caution when taking CBD products by mouth alongside high-fat meals. High-fat meals can dramatically increase the blood concentrations of CBD, which can increase the risk of side effects.

The FDA does not regulate CBD products in the same way they regulate drugs or dietary supplements, so companies sometimes mislabel or misrepresent their products. That means it’s especially important to do some research and find a quality product.

While many studies have suggested CBD oil is helpful for pain, more research is necessary, especially long-term studies with human subjects.

However, CBD oil does show promise as a treatment for pain. Some scientific and anecdotal evidence suggests that it can help people manage chronic pain in various contexts.

CBD oil is especially promising due to its lack of intoxicating effects and a possible lower potential for side effects than many other pain medications.

People should discuss CBD oil with their doctor if they are considering using it for the first time.

What precautions would you advise if someone wants to try CBD oil to treat pain?

Users should follow legal channels to obtain CBD.

The science is emerging to support its use, especially in a time where most people want to avoid addicting opioids while treating chronic pain.

Because of the changes in social acceptance for the use of the marijuana plant and the urgency to address the opioid crisis, there is funding for clinical trials.

A 2017 study found CBD was effective for chronic neuropathy pain. It may have a role in reducing inflammation as well.

An individual should talk to a doctor first, start with the lowest doses possible, read the information available, and be an informed consumer.

Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT Answers represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.

Is CBD legal? Hemp-derived CBD products with less than 0.3% THC are legal federally but still illegal under some state laws. Cannabis-derived CBD products, on the other hand, are illegal federally but legal under some state laws. Check local legislation, especially when traveling. Also, keep in mind that the Food and Drug Administration (FDA) have not approved nonprescription CBD products, which may be inaccurately labeled.

Last medically reviewed on November 3, 2020

Cannabidiol or CBD oil has become popular for pain treatment. This article looks at how it works, how to use it, and the benefits and risks of CBD oil.