Posted on

how to use cbd oil for neuropathy

The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities

Affiliations

  • 1 PGY-2, Department of Podiatric Medicine and Surgery, Scripps Mercy Hospital, San Diego, CA 92103, United States.
  • 2 Podiatric Surgery Section Chief, Scripps Mercy Hospital, 4077 Fifth Ave, MER35, San Diego, CA, 92103, United States.
  • 3 Department of Podiatric Medicine and Surgery, Scripps Mercy Hospital, San Diego, CA 92103, United States.
  • 4 Private Practice, San Diego Podiatry Group, San Diego, CA, 92108, United States.
  • 5 Department of Microbiology, Immunology & Pathology, Des Moines University, Des Moines, IA, 50312, United States.
  • 6 Department of Surgery, University of Missouri School of Medicine, Columbia, MO, 65212, United States.
  • PMID: 31793418
  • DOI: 10.2174/1389201020666191202111534

The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities

  • Search in PubMed
  • Search in NLM Catalog
  • Add to Search

Authors

Affiliations

  • 1 PGY-2, Department of Podiatric Medicine and Surgery, Scripps Mercy Hospital, San Diego, CA 92103, United States.
  • 2 Podiatric Surgery Section Chief, Scripps Mercy Hospital, 4077 Fifth Ave, MER35, San Diego, CA, 92103, United States.
  • 3 Department of Podiatric Medicine and Surgery, Scripps Mercy Hospital, San Diego, CA 92103, United States.
  • 4 Private Practice, San Diego Podiatry Group, San Diego, CA, 92108, United States.
  • 5 Department of Microbiology, Immunology & Pathology, Des Moines University, Des Moines, IA, 50312, United States.
  • 6 Department of Surgery, University of Missouri School of Medicine, Columbia, MO, 65212, United States.
  • PMID: 31793418
  • DOI: 10.2174/1389201020666191202111534

Abstract

Background: Peripheral neuropathy can significantly impact the quality of life for those who are affected, as therapies from the current treatment algorithm often fail to deliver adequate symptom relief. There has, however, been an increasing body of evidence for the use of cannabinoids in the treatment of chronic, noncancer pain. The efficacy of a topically delivered cannabidiol (CBD) oil in the management of neuropathic pain was examined in this four-week, randomized and placebocontrolled trial.

Methods: In total, 29 patients with symptomatic peripheral neuropathy were recruited and enrolled. 15 patients were randomized to the CBD group with the treatment product containing 250 mg CBD/3 fl. oz, and 14 patients were randomized to the placebo group. After four weeks, the placebo group was allowed to crossover into the treatment group. The Neuropathic Pain Scale (NPS) was administered biweekly to assess the mean change from baseline to the end of the treatment period.

Results: The study population included 62.1% males and 37.9% females with a mean age of 68 years. There was a statistically significant reduction in intense pain, sharp pain, cold and itchy sensations in the CBD group when compared to the placebo group. No adverse events were reported in this study.

Conclusion: Our findings demonstrate that the transdermal application of CBD oil can achieve significant improvement in pain and other disturbing sensations in patients with peripheral neuropathy. The treatment product was well tolerated and may provide a more effective alternative compared to other current therapies in the treatment of peripheral neuropathy.

Keywords: CBD; cannabis sativa; diabetic neuropathy; hemp; nerve pain; review..

Our findings demonstrate that the transdermal application of CBD oil can achieve significant improvement in pain and other disturbing sensations in patients with peripheral neuropathy. The treatment product was well tolerated and may provide a more effective alternative compared to other current the …

Does CBD oil help neuropathic pain?

We include products we think are useful for our readers. If you buy through links on this page, we may earn a small commission. Here’s our process.

Applying cannabidiol (CBD) oil to a painful area or taking it orally may help relieve neuropathy pain. However, more research is needed to establish the safety and efficacy of CBD products.

Black and white photo of hands using cbd oil bottle dropper for neuropathy, isolated over green background with cannabis leaf

Is CBD legal? Hemp-derived CBD products with less than 0.3% THC are legal federally but still illegal under some state laws. Cannabis-derived CBD products, on the other hand, are illegal federally but legal under some state laws. Check local legislation, especially when traveling. Also, keep in mind that the Food and Drug Administration (FDA) have not approved nonprescription CBD products, which may be inaccurately labeled.

Neuropathy causes chronic pain due to damaged nerves. It can be excruciating, and sometimes, doctor-prescribed medicines fail to provide enough pain relief. Some people may look to alternative remedies, including CBD oil.

CBD oil comes from the cannabis plant. CBD products do not usually contain tetrahydrocannabinol (THC), which is the ingredient that causes the high that people associate with cannabis. When a product does contain THC, the quantities are generally very low.

Researchers are studying the effectiveness of CBD oil for many conditions, including chronic pain. Research also continues into how safe CBD products are.

Individuals may find it challenging to choose a safe CBD oil product because of the lack of consistent government regulation. Some studies show that certain products are not labeled correctly and could include unexpected ingredients or quantities.

The Food and Drug Administration (FDA) have not approved the safety, effectiveness, or quality of the over-the-counter CBD products.

However, to protect an individual’s health, they can take action against CBD companies that make baseless health claims.

Individuals can apply CBD oil to the skin or take oral capsules to assist with neuropathy. Research is ongoing into their efficacy and safety. Read more here.