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does cbd oil interact with methotrexate

Taking CBD And Methotrexate?

For those of you taking both cbd and mtx. how do you take the two? Take cbd on days except injection day? I was using just cbd from an excellent company, it was a 1:25 ratio. But now just on mtx and suffering with no sleep etc. What is everyone else taking? Are you concerned about interaction? What do your Rheumatologist say? Dosages?
Thanks for any and all info you can provide. I would like to use cbd to manage side effects but my doctor is not supportive of combining both and… read more

My dr. said it was fine with him and I didn’t find a cross reaction to mtx. You can check on for interactions. I just take maybe half a dropper to help pain and sleep at before bed if I need it, but you have to experement yourself with it, no rules far as I know. Hope get to feeling better!

I take cbd before I go to bed it helps me sleep better

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For those of you taking both cbd and mtx…. how do you take the two? Take cbd on days except injection day? I was using

Cbd oil and methotrexate : Hi, I’ve been taking cbd oil. – NRAS




Cbd oil and methotrexate

Hi, I’ve been taking cbd oil for 4 months and with some of my meds I have to leave a 4-hour gap and 2-hours with others. I started back on methotrexate injections last week, didn’t have my cbd oil that night at hardly slept! Does anyone know how long a gap I need between mtx and cbd oil? Tia xx

  • Methotrexate
  • CBD

Don’t know, I’m thinking there would be very little experience regarding the gap between CBD oil and MTX. I don’t remember reading of someone who’s taking both together

Thanks for your reply xx

This type of problem is going to crop up more often as more people choose to use CBD oil alongside their meds. I don’t think you’ll find the answer on CBD oil sites. You’d need to broach the subject with a medical professional or a pharmacist I would think, you need proper advice. Maybe you could ask your Rheumy. Not wanting to sound preachy but it’s always best to discuss anything you’re considering taking supplement wise with the original prescriber, I’m on MTX & going to ask mine at my appointment in December. My h is already set for his & I’d like to know if it could be something I could dip in & out of when needed, more for my OA than RD though.

Thanks for your reply. My rheumy is fine with me taking cbd oil but didn’t know about the time between meds. She said to ask a pharmacist, who didn’t know. I’ve found the answer from searching on here. Should have done that first 😊 xx

So. Don’t leave us in suspense, what is it?! 🙃

Oh, & where do you buy yours from, if you don’t mind sharing?

Hi, my best advise would be to join CBD users united – UK on Facebook. I told I had RA and sjogrens and what I wanted help with. They advised me to start low and slow. They’ve helped me to choose different oils when I’ve needed to use a stronger one. I started on CBD Brothers green. I would not be where I am today if it wasn’t for the fb group xx

Thank you Mary, that’s just what I wanted to know. Unfortunately though I’m not on Facebook so shall look up CBD Brothers. It does concern me when I read of people just buying canabidiol willy nilly from wherever, not knowing the quality or even if they’re starting on the correct strength. This is why I’ve not dipped my toe yet but that helps.

Can you let me know if there’s any need to leave a gap between MTX & CBD oil. I suspect not but it would be good to know for sure. Thanks again.

Cbd brothers and cheds cdb oils are both reputable sellers. There are more but I don’t know them 😊. I started on cbd bros green oil 1 drop 3 times a day and increased to 2 drops on week 2, 3 on week 3, etc. It’s important to take it slow. I’ve been advised to leave 4 hour before and after my blood pressure tablets and aspirin and 2 hours for other meds. The info I saw said at least 2 hours for mtx, so I will leave 3 hours xx

Thanks again, & for the other seller. If my Rheumy ok’s it I shall go through my other meds with her, just to be sure there are none that are no no’s with it or any others that need spacing. x

Do you know how many mg are in each of the green drops you take and the total per day? I began taking cbd oil 2 weeks ago and it is helping me in more ways than one. Presently I’m taking a 1500mg raw green paste in a syringe, each rice size is 5 mg and I’m splitting it up in 3 doses for a total of 35mg/day. I also am taking methotrexate injections. I have been leaving about 2 1/2 hrs between.

You are so right, we all want to do the best for ourselves. I have been toying with the CBD-oil idea for some time. My GP is ok about his prescriptions, advises seeking clearance from Rheumatologist for my jak-inhibitor; so I’ll do that at my Sept consultation, if not before. Folk talk of specialist suppliers. I would like to know opinions/advice, please, re- the high street: Holland & Barrett sell a selection, in various strengths, off the shelf.

It sounds as though the CBD oil really helps you. what strength do you take ? Has the Rheumy told you any reasons not to take it ? Thanks. – Sorry not on MTX or CDB oil – so cant help on that side of things.

Hi, rheumy is fine about cbd oil. She said quite a few of her patients take it. I’ve worked up to 3 different oils ranging from 4-6%. Cbd oil has helped me with fatigue, insomnia and some pain xx

MadMazzy where do you get it from I need this in my life 😱😱😁

It has been discussed quite a lot janny55, if you check Pinned Posts (top right) there are some there. For more enter CBD oil in the Search Healthunlocked box & under Filter results – Posted in – View more & select NRAS & more will appear.

Thank you nomoreheels will be having a look 👀😁

Hi, I’ve been looking into this a lot as I’d like to try it, haven’t taken the plunge yet! There is a site called cbd brothers which gives a bit of info and also one called Simple?

I’ve joined a couple of fb groups and there’s lots of info there too.

Ooooh thanks Sjhoney I know I would love to try it but a bit scared 😱🤗 good luck too let me know if you take the plunge 👍😁x

Hi, see my reply to nomoreheels, best to join the Facebook group. There are a lot of unscrupulous people out there, willing to take your money for poor products xx

Thanks MadMazzy will have a look 👀 😁👍x

There just isn’t enough evidence based research yet. As more people combine CBD and MTX there will be more research available.

I did find this though:

Thank you for sharing experiences (which are the closest thing to research: case studies) and for asking this question.

P.s: I’m getting good results with Select CBD used both subliminally and topically. I wanted one that had no THC in it. I can’t take THC I don’t react well to it. I also just got Joy Organics for the same reason.

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Hi, I’ve been taking cbd oil for 4 months and with some of my meds I have to leave a 4-hour gap and 2-hours with others. I started back on methotrexate injections last week, didn’t have my cbd oil…