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6 of the Strongest CBD Oils You Can Buy Online 2021

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If you’re after the strongest CBD oil on the market, you’ve come to the right place. Cannabidiol, better known as CBD, is extremely popular for its therapeutic potential that may help soothe a variety of ailments, including chronic pain, seizures, anxiety, and more. For those who are looking for serious relief, the highest-concentration oil drops may be what it takes to get the job done—particularly if they haven’t noticed any reprieve with lower-strength oils.

Our picks for strongest CBD oils at a glance:

  • Best Full Spectrum:Spruce Max Potency Lab Grade CBD Oil
  • Best Variety: CBDistillery
  • Best THC Free: Medterra Isolate CBD Oil
  • Best Organic:NuLeaf Naturals
  • Best for Nighttime:Cornbread Hemp Whole Flower CBD Oil
  • Best Taste: FAB CBD

We’ve got you covered with the top six strongest CBD products that we’ve determined—through extensive research, testing, and experimentation—are the highest-quality products available on the market.

Below, read more about strong CBD oils, including what determines their strength, how much to take, and more details on the oils we recommend.

Top 6 strongest CBD oils available online

Best Full Spectrum: Spruce Max Potency Lab Grade CBD Oil

Strength: 2,400 mg per 30 mL bottle (80 mg CBD per 1 mL dropper)

Type: Full Spectrum

Spruce is a family-owned business focused on making small, high-quality batches of high-potency CBD products via moonshine extraction techniques. This is a beautiful, straightforward oil with no added flavors or preservatives, just two all-natural ingredients: organic hemp oil and full-spectrum CBD oil. Spruce CBD oil is on the pricier end, but you get a pristine product—in this case, a high-strength formula with a full range of cannabinoids and terpenes in every bottle.

Best Variety: High Potency CBDistillery CBD Oils

Strength: 2,500 mg or 5,000 mg per 30 mL bottle (83 mg per dropperful and 167 mg per dropperful, respectively)

Type: CBD isolate, broad-spectrum, and full-spectrum options available

By far the strongest CBD oil on our list is CBDistellery’s 5,000 mg CBD oil. It’s an excellent choice if your chronic pain requires higher doses—and the price is friendly, too. This seriously potent product is available in full-spectrum, broad-spectrum, and isolate, so you can enjoy your preference. CBDistillery also offers a very strong 2,500 mg CBD oil if 5,000 mg is too much.

Best THC Free: Medterra Isolate CBD Oil

Strength: 3,000 mg per 30 mL bottle (100 mg CBD per 1 mL dropper)

Type: CBD isolate

If you’re after a pure CBD isolate, you can’t go wrong with Medterra’s high-quality—but still affordable—CBD oil. Its CO2 extraction process removes 100% of THC, leaving just absolute, high-strength CBD infused in organic MCT oil. Medterra also offers a high-potency broad-spectrum CBD oil that contains 2,000 milligrams of CBD and runs at $100 per bottle. With various flavors to choose from, such as citrus and strawberry mint, this is a tasty alternative to the unflavored isolate.

Best Organic: NuLeaf Naturals

Strength: 1,800 mg per 30 mL bottle (60 mg per 1 mL dropper)

Type: Full Spectrum

If organic is important to you, NuLeaf’s high-strength CBD oil tincture—while not quite as potent as other options listed here—is a fantastic choice. NuLeaf grows all of its own hemp plants in Colorado and ensures healthy and organic cultivation practices. From these plants, it utilizes a CO2 extraction method to produce a potent, full-spectrum oil that’s suspended in hemp seed oil for additional health benefits. Do note that while there are a range of bottle sizes (you’ll also see 3,000 and 6,000 milliliters), the actual potency of all these bottles is the same.

Best for Nighttime: Cornbread Hemp Whole Flower CBD Oil

Strength: 1,500 mg per 30 mL bottle (50 mg CBD per 1 mL dropper)

Type: Full Spectrum

Cornbread Hemp Extra Strength Whole Flower CBD Oil contains up to 50 mg of CBD per serving, as well as a range of naturally-occurring terpenes, flavonoids, fatty acids, and cannabinoids. It’s USDA organic, vegan, gluten-free, non-GMO, third-party lab tested for purity, and gives you access to as many beneficial plant compounds found in the hemp plant as possible. This formula is a great choice for nighttime use as it can help you relax and get restful sleep.

Best Taste: FAB CBD

Strength: 2,400 mg per 30 mL bottle (80 mg per dropperful)

Type: Full spectrum

Don’t like the earthy hemp taste of CBD oil? FAB CBD offers high-potency CBD oils in a range of yummy flavors, including citrus, mint, berry, and vanilla (there’s also “natural,” for people who like to keep it simple). Depending on the flavor you choose, the CBD will be blended in fractionated coconut oil or a coconut oil/sunflower oil combination with stevia. All taste good and still provide the full spectrum support you need in a vegan, non-GMO oil. If you’re not into it, FAB CBD offers a 30-day money-back guarantee.

Why CBD Potency Matters

CBD has an incredible array of health benefits. Studies indicate that CBD may provide pain relief, reduce inflammation, and even ease anxiety, depression, and psychosis. Some of these conditions, though may require a strong dose of CBD in order for a person to experience relief, and this is where high-potency CBD oil comes in. You should never start out taking an extra-strong CBD oil if this is your first time trying CBD—start with an average-strength CBD oil (something between 500 and 750 milligrams per 30 milliliter bottle) and play around with the dosage to see what works best for you.

How Do I Determine CBD Oil Strength?

CBD oil products typically vary in strength from mild to extra-strong. When shopping around for the right oil for you, consider the following:

  • An average-strength oil will contain a range of 500 to 750 milligrams of CBD per 30 milliliter bottle
  • A strong CBD oil will typically contain between 1,000 and 1,500 milligrams per 30 milliliter bottle
  • An extra-strength potency would be in the 2,000+ milligrams range of CBD per 30 milliliter bottle

But it’s not just the CBD concentration that makes a tincture strong; there are other factors that you’ll want to keep in mind as well. For instance, the type of hemp extract used to create the product (i.e. full spectrum, broad spectrum, or isolate) may also play a factor in its overall strength.

Full Spectrum vs. Broad Spectrum vs. Isolate

Let’s start with full spectrum CBD oil. This is made with whole plant extract with nothing removed or added, so it’s totally natural. The least manipulated of the CBD oil options, full spectrum maintains a full range of cannabinoids and terpenes, resulting in the desirable entourage effect, in which all of the compounds work together to provide the greatest benefits a CBD oil can provide.

However, full spectrum can have a notable THC content. While full spectrum CBD products will not get you “high” because they contain only trace amounts of the primary psychoactive ingredient within the cannabis plant (less than 0.3%, according to federal regulations), some consumers prefer to eschew the compound altogether.

Broad spectrum implies a greater level of control over the final outcome of the CBD tincture than full spectrum options. While some compounds have been removed, including traceable amounts of THC, broad spectrum products still maintain a broad range of cannabinoids and terpenes to enhance the formula and ensure you receive its benefits.

CBD isolate is what we call pure CBD. That means that solely CBD has been extracted from the plant and no other plant constituents are in the product. The benefit of an isolate is that it contains absolutely zero THC, which is a great option for anyone concerned with passing a drug test. On the other hand, isolate oils may need more overall CBD content to be considered as effective as the whole plant medicine within full and broad spectrum CBD oils.

How Much CBD Oil Is Too Much?

The amount of CBD oil a person needs will depend entirely on the individual, as everyone responds differently. Factors like body weight, metabolism, body chemistry, and the target symptoms will all play a role in the effects felt from CBD.

The best way to determine the right dosage for you is to start small and add more incrementally. Stop at the dosage that gives you relief and makes you feel better. If you experience uncomfortable side effects, lower the dose.

This process is crucial in finding the right CBD oil (and the right potency) for you, and it can help prevent unwanted side effects like nausea, fatigue, and irritability. These adverse reactions are not common, but some people do experience this type of discomfort if they take too much CBD.

If you’re an experienced CBD consumer, you may be comfortable experimenting with high-strength CBD oils. Just keep in mind that CBD may affect certain medications, such as the blood thinner coumadin, so you’ll want to be extra cautious of your CBD dosage if you are on prescription medications. If this is the case, check with your physician before incorporating a strong CBD oil into your daily regimen.

What’s the Best CBD Oil for You?

When choosing the best CBD oil for you, there will likely be some trial and error. Just as it takes some experimentation to discover the perfect dose for your body and symptoms, it can take patience finding the best product for you as well.

There are an overwhelming number of companies within the CBD industry, and while you’re wading through the options, the main thing you want to look for is transparency—specifically in the following categories:

  • Third-Party Lab Test Results: To ensure you’re getting a high-quality CBD product, check out the certificate of analysis (CoA). This is a record of independent, third-party testing for each batch of product made. The lab results will indicate the exact cannabinoid composition and the potency of the product, and it will confirm that the oil is free of any unwanted contaminants, like heavy metals or pesticides. The results should also match the information provided by the brand for the particular product, and if a CBD company doesn’t readily publish its CoAs, shop elsewhere.
  • Hemp Sourcing: Is the CBD extract being sourced from small family farms or large industrial farms? Brands should be transparent about their plant source, whatever it is. Also keep in mind that American-grown hemp is regulated by domestic laws and will be more dependable than international hemp.

It’s also important to note that while the FDA has not evaluated these CBD products, most studies conclude that CBD is generally safe to consume. Still, it’s always a good idea to check with your physician if you have a serious medical condition or take prescription medications before experimenting with a strong CBD oil.

Maggie Rossell is a certified herbalist, world traveler, and devoted writer. She loves to explore plants and the human experience—and how the two interweave both physiologically and culturally. Her mission is to spark curiosity and inspiration in readers.

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Are you on the hunt for the strongest CBD oil? Discover what makes a CBD oil strong and where you can buy quality CBD oils with the highest potency. Shop CBD oils from CBDistillery, Spruce, FAB CBD, Medterra, and NuLeaf Naturals.

Potency Testing

cannabinoid potency samples in test tubes

Accurate determination of cannabinoid concentrations in cannabis and CBD samples is one of the important components of cannabis & CBD testing. ACS determines 20 different cannabinoids and quantifies the level to a specific amount. Our Ultra-High Performance Liquid Chromatographs deliver the highest accuracy that end users can depend on.

POTENCY TESTING

MATRIX: Flowers/Plants, Derivative Products and Edibles
ANALYTES: 20 count
INSTRUMENT: LCUV

Potency 11 (Standard Cannabinoids)

  • Δ9-THC
  • Δ8-THC
  • THCA
  • THCV
  • CBD
  • CBDA
  • CBDV
  • CBG
  • CBGA
  • CBC
  • CBN

Additional (Optional: Total 20)

  • CBNA
  • CBCA
  • CBDVA
  • CBL
  • THCVA
  • CBT
  • Δ8-THCV
  • EXO-THC
  • Δ10-THC

Potency 12 (Includes Δ8 & Δ10)

  • Δ10-THC
  • Δ9-THC
  • Δ8-THC
  • THCA
  • THCV
  • CBD
  • CBDA
  • CBDV
  • CBG
  • CBGA
  • CBC
  • CBN

Additional (Optional: Total 20)

  • CBNA
  • CBCA
  • CBDVA
  • CBL
  • THCVA
  • CBT
  • Δ8-THCV
  • EXO-THC
  • Δ10-THC

TESTING POTENCY BEYOND THC & CBD

Cannabis potency testing measures the cannabinoids present in your cannabis sample and measures the strength of those compounds. ACS Lab uses an Ultra High-Performance Liquid Chromatography (HPLC), which is the preferred instrument for testing cannabis edibles and extracts due to its ability to test samples at room temperature without requiring a catalyst to produce a heat reaction. This method can also test for THC Acid (THCA) and CBD Acid (CBDA), which a gas chromatograph would not.

CONSUMERS ARE DEMANDING MORE INSIGHT

When deciding which cannabis strains best suit your consumer’s needs, it’s vital to consider the cannabinoids present in your products as well as their potency. Cannabinoids are chemical compounds secreted by cannabis flowers that mimic the effects of endocannabinoids, which are naturally produced by the human body. Endocannabinoids interact with the human body’s endocannabinoid system (ECS), which helps us maintain homeostasis . Thus, cannabinoids can be a vital part of human health and determine your product’s therapeutic value.

LOOKING FOR BETTER POTENCY TEST RESULTS?

Cannabinoids occur mostly in the plant resin that’s produced by the structures known as trichomes. Trichomes help protect cannabis from insects, animals, fungi, light contaminators and other environmental attackers. The sticky resin is also rich in terpenes , which are responsible for the plant’s smell, taste and therapeutic effects.

To help influence your plant’s cannabinoid profile, the best method is to select a seed whose genes have the potential to produce the potency you desire. For example, if you live in the mountains, you may select a seed that was specially bred for high-altitude growth. But you may also influence how much resin a plant produces through its micronutrients, temperature exposure, humidity levels, harvest methods and water quality.

Heat, for example, can hinder resin formation, so you may want to keep temperatures as low as possible–especially in the late stages of the plant’s bloom cycle. You also want to pay close attention to trichome color throughout the harvest. When trichomes are clear and translucent, they’re not ready for processing yet. But as you notice the trichomes lose opacity and form an amber hue, you know that the plant has reached optimal levels of cannabinoids.

LEGAL & SCIENTIFIC DRIVERS FOR POTENCY TESTING

As laws continue to change in the U.S., the need for standardized and consistent potency testing is necessary to keep consumers safe from unwanted side effects. For hemp, potency testing is required to prove that it contains less than the maximum limit of THC (0.3%).

Potency testing also allows scientists to research how cannabinoids may work differently based on whether they are contained in flower, oils or topicals. This type of research can enhance the ability to market your product to the targeted customer that could benefit from its effects the most.

It’s also important to understand your product’s potency to meet market demand for high THC or CBD levels. You can also utilize potency results to educate your customers with information they need to determine the proper dose for their specific symptoms. When a product’s cannabinoid profile is transparent and documented, customers can work with their dispensary professional to find the best strain for them.

For example, cannabinoids interact with the body’s ECS by connecting to various endocannabinoid receptors that are present in the brain (known as CB-1 receptors) and throughout the body (CB-2 receptors). Depending on which CB receptor the cannabinoid attaches to, the effects on the body can be significantly different, which can be important if you’re considering a cannabis strain that is needed for pain relief, for instance, as opposed to mood regulation. Cannabis plants can produce anywhere between 80-100 different types of cannabinoids that synergize to make up the therapeutic and cognitive effects of the strain. The two most in-demand cannabinoids are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), but other compounds such as cannabinol (CBN) are also starting to emerge. Customers understand these compounds at a basic level and expect to see potency levels that match their desired effects.

POTENCY TESTING WITH ACS LABORATORY

At ACS Laboratory, we currently test flower, edibles and extracts for 20 different cannabinoids, which can alleviate symptoms related to several common conditions: mood and behavior disorders, gastrointestinal and neurological ailments, and pain and sleep-related issues, to name a few. Refer to the FAQ section below that explains more about each cannabinoid as well as the importance of potency testing.

FAQS ABOUT POTENCY TESTING

No. The two primary ways in which cannabis potency is tested is either by Gas Chromatography (GC) or High-Performance Liquid Chromatography (HPLC). Some companies use GC due to its speed of analysis and simplicity in finding common cannabinoids like THC, CBD or cannabinol (CBN). This method imitates the process of heating the cannabis product, so if the product will be smoked, this method can provide insight on the potency of different cannabinoids in this form.

However, because heat is required in this process, acid forms of cannabinoids like THCA or CBDA cannot be identified. This is where HPLC becomes a favorable way to test cannabis potency because it can identify the acid molecules of major cannabinoids before they will convert to their corresponding compounds through the heat of smoking or baking. HPLC instruments use an ultraviolet wavelength detector to identify the cannabinoids, so it is much more inclusive of various forms of cannabinoids in their free form or acidic state. HPLC is often the preferred choice for potency testing.

Two issues that can affect a hemp plant’s cannabinoid profile are the time of year and the terrain in which it’s planted. Other factors include chemical exposure and environmental stress. That is why you may want to start potency testing during the plant’s vegetative state.

Through vegetative potency tests, laboratories like ACS can analyze plants early in their life cycles to identify the CBD and THC potency. This test helps you avoid the time-consuming process of raising up seedlings to maturity and waiting to test the flower after harvest. It helps enable more rapid development that provides patients and consumers with the quality and safety they expect.

Finally, you’ll want to retest your cannabis post-harvest once your product has been manufactured. This will guarantee that the levels match what you expect.

ACS Lab currently tests for the 16 cannabinoids below, plus 4 new ones ( ᐃ8-THCV, ᐃ10-THCV, EXO-THC, CBT)

In our dedicated Florida laboratory we test potency levels of 16 core cannabinoids including THCA-A, CBD, CBDA, CBG, THCV, CBC, CBN, CBGA, Δ9-THC, Δ8-THC, CBDV, CBNA, CBCA, CBDVA, CBL and THCVA.