‘Should I Be Vaping CBD?’: Why Vaporization Works Better Than Ingestion
This article is sponsored by CV Sciences, Inc. CV Sciences is one of the leading suppliers and manufacturers of agricultural hemp-derived CBD bulk and finished products, namely their PlusCBD Oil and Purified Liquids brands.
“There’s more than one way to skin a cat” is a weirdly morbid saying, but the phrase’s core concept rings true – there are a lot of ways to accomplish the same task. This has never been more true for cannabidiol (CBD). With the rising demand for CBD products, there are a plethora of different ways to get your daily dose. They range from sublingual sprays, to vaping CBD oils, to smoking good old-fashioned joints. Yet most people don’t know that the way in which you ingest CBD can drastically alter its effective dosage.
CBD’s Bioavailability: Understanding Its Variations
In general, not all of the CBD you consume will directly affect your body: only a certain percentage will be able to enter your systemic circulation and produce its active effects. This percentage is referred to in science as “bioavailability,” and it strongly depends on the manner in which CBD is introduced to your system. For example, the oral bioavailability of CBD is roughly 15 percent. That means for every 100 milligrams of CBD that you eat, only 15 milligrams will actually reach your bloodstream.
There are two main reasons why this happens. First, CBD is hydrophobic, meaning that it is not very water-soluble. In the same way that oil does not like to mix with vinegar, CBD does not like to stay in your bloodstream. Instead, it rapidly diffuses out of your blood and accumulates into your fatty tissues. Unfortunately, this significantly reduces the amount of bioactive CBD that can enter your systemic circulation, allowing for less CBD to be carried to its active sites in your body and thus lowering its overall bioavailability.
Second, when an organic compound like CBD enters your gut, it has to pass through the liver before it enters your circulation. During this transition, the liver will actively reduce the amount of CBD, either through absorption or through chemical breakdown by liver enzymes. This phenomenon is called the “first-pass effect,” where passing through the liver reduces the concentration of bioactive compounds.
Maximizing CBD’s Effects: How to Offset CBD Loss by Vaporizing
There are a few different ways to offset these losses of CBD. For one, you can reduce the amount of CBD that dissolves out of your bloodstream by putting the CBD into a form that is more hydrophilic, or water-soluble. However, this can only be achieved by complicated chemical means, such as through the use of cyclodextrins or liposomes. A more practical solution is to bypass the first-pass effect of oral administration entirely by utilizing vaporization.
During vaporization, CBD enters your lungs and diffuses directly into your bloodstream rather than passing through your gut and liver. This avoids the first-pass effect altogether, allowing nearly four times as much CBD to enter your circulation for a maximum bioavailability of roughly 50 to 60 percent. Essentially, this means you can achieve the same beneficial effects with a much smaller amount of CBD.
Not only that, but vaping will greatly decrease the amount of time it takes for the CBD in your body to become active, since you don’t have to wait for it to travel through your gut. By vaporizing a CBD e-liquid or high-CBD concentrate, you could potentially feel its effects 30 to 60 minutes faster. This makes vaping CBD an extremely efficient delivery method.
Of course, if you’re leaning towards embracing the vape life, make sure you’ve done your research on the concentrate you intend to consume. Without sufficient regulatory oversight in the emerging vape and cannabis industries, few companies have been able to produce a clear and homogenous CBD solution, so the milligram amount in CBD products is often inconsistent with the amount claimed on the label. Be sure to ask for both in-house and third-party test results from your chosen source to ensure you’re getting a quality product!
Andrew Pham currently serves as the Lead Scientist at CV Sciences, Inc. He was formerly the Lead Scientist at SC Laboratories, a prominent third-party analytical testing lab. He is also an executive member of the Cannabis Chemistry Subdivision (CANN) of the American Chemical Society.
There is a plethora of ways to get your daily dose of CBD, but the way you ingest it can alter its effectiveness. Learn why vaping CBD tends to work best.
CBD Vaping – What’s the Difference Between CBD E-Liquid and CBD Oil?
By Emily Ledger
Cannabidiol – known more generally by its abbreviation, CBD – is becoming commonplace in the UK market. A growing collection of products now incorporate the product. In fact, the cannabinoid can now be found in chocolates and drinks and even in clothing and pillows, to name a few!
Yet, CBD oils and e-liquids remain among the most popular products on the market. Although they might look much the same, it is important not to mix them up CBD oils and e-liquids. So, what is the difference between them?
The non-psychoactive cannabis derivative has been found to have a number of potential benefits, from relieving feelings of stress and anxiety to improving sleep and even reducing pain. Vaping and the use of sublingual (under the tongue) drops are two of the most popular ways of taking CBD.
The popularity of these products is probably owed to the high bioavailability that they offer. Bioavailability refers to the percentage of the compound that is effectively absorbed by the body. Vaping and sublingual application happen to have some of the highest rated of absorption for CBD consumption.
What is a CBD E-Liquid?
Vaping has become increasingly common around the world, as many people look for a less unhealthy alternative to smoking. In many cases, vape products may contain nicotine to ease the transfer from smoking to vaping. However, a growing number of people are now looking to vape products for other uses – namely, as a way to safely and conveniently incorporate CBD into their everyday lives.
CBD e-liquids, also known as CBD vape juices, are applied to vape pens which convert the liquid into vapour. This vapour is then inhaled by the consumer. Other products available on the market include ready-filled CBD pens. Vaping is believed to be the most effective way to administer CBD, thanks to high absorption in the lungs.
What are CBD Oils?
CBD oils or tinctures are becoming increasingly common and can be easily sourced from many stores, both online and on the high street. These oils can be used in a number of ways, including being dropped and held under the tongue, and applied topically (directly to the skin).
These products are often sold with a dropper and are known as ‘tinctures’. They allow for easy application, both sublingually (under the tongue) and topically. Second to vaping, CBD is believed to have amongst the highest bioavailability when applied sublingually. This is due to thin barriers between skin surface and veins under our tongues.
Although these products are perfectly safe for oral and topical consumption, they shouldn’t be confused with e-liquids/vape juices and inhaled as a vapour.
What is the Difference Between E-Liquids and Oils?
CBD e-liquids and oil products often look very similar, with both commonly sold in small glass bottles. However, each product is designed specifically for its intended use and should not be mixed up.
CBD oil products are usually made by combining a CBD extract with a food-grade oil – commonly olive, hemp, or coconut oil. Some oils may also contain flavourings to make the oil taste more pleasant for oral consumption. These products were not designed to be exposed to high heats for vaporisation, unlike CBD vape juices / e-liquids. Using CBD oils that were not designed to be vaped may result in an unpleasant and potentially harmful vapor as well as possibly damaging the coil of your vape pen.
E-liquids are made using a CBD extract alongside a thinning agent such as PG/VG or MCT. These ingredients ensure that the liquid is thin enough to be vaporised effectively, producing a clean and comfortable vapor for inhalation. It is important to note that it is possible that CBD oils that were not designed for vaping may also contain MCT for thinning. However, this does not mean that it is safe for the purpose of vaping. To make a safe and effective e-liquid, these agents must be present in the correct proportions.
Always Check the Label
To ensure you are using your CBD products as they were, make sure to always check the labels. If the product is referred to as a ‘tincture’, then it probably isn’t intended to be put into a vape pen. The ‘How to Use’ directions on the packaging will also give you a guide to how the product is supposed to be applied. Above all, always buy your CBD products from trustworthy and responsible brands!
To avoid confusion, it may also be a good idea to simply buy a ready-filled CBD vape pen. This will take all the guesswork out of vaping the cannabinoid. There are a number of brands on the market that produce CBD pens, such as Hiatus. As well as being guaranteed the right product, this also makes dosing much more straightforward!
Although CBD oils and e-liquids might look much the same, it is important not to mix them up when vaping. So, what is the difference between them?