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Hemp Protein

Hemp is a food product derived from the same plant of which Marijuana originates from, but without intoxicating components; the protein fragment appears to be a popular meal replacement supplement but is not yet linked to unique properties (relative to other Protein supplements).

Our evidence-based analysis on hemp protein features 23 unique references to scientific papers.

This page is regularly updated, to include the most recently available clinical trial evidence.

Each member of our research team is required to have no conflicts of interest, including with supplement manufacturers, food companies, and industry funders. The team includes nutrition researchers, registered dietitians, physicians, and pharmacists. We have a strict editorial process.

This page features 23 references. All factual claims are followed by specifically-applicable references. Click here to see the full set of references for this page.

Kamal Patel

Primary information, health benefits, side effects, usage, and other important details

Hemp protein is a industrial byproduct from hempseed where the seeds (balanced macronutrient profile) have their oil extracted into Hempseed oil, and the remainding seedmeal that is high in protein relative to the seeds is then processed into Hemp protein supplements.

Hemp that is currently on the market is a strain low in THC (the intoxicant and psychoactive agent in Marijuana) and does not confer intoxicating properties. It is usually not a pure protein supplement, as it has up to 10% fatty acids by weight (pretty balanced between omega-3 and omega-6 fatty acids and generally high in polyunsaturated fatty acids) and confers a higher inherent fiber content relative to other Protein supplements. The protein portion of hemp is not a complete protein source, due to being low in Lysine (the rate limiting essential amino acid); it is also relatively low in leucine, but is relatively high in both L-Tyrosine and Arginine.

There is a cannabinoid content in Hemp, although they are cannabinoids that do not interact with the two classical cannabinoid receptors in the human body and are unlikely to have the same neural properties attributed to marijuana. These may confer some health properties unique to hemp products (either hempseed protein or Marijuana) but in the context of using hemp protein as a meal replacement they are not studied.

Currently, hemp protein appears to be a viable meal replacement option and has the benefit of having a higher fiber content but is not yet linked to unique health benefits (or harms) to establish its importance over other dietary sources of protein.

Hemp is a food product derived from the same plant of which Marijuana originates from, but without intoxicating components; the protein fragment appears to be a popular meal replacement supplement but is not yet linked to unique properties (relative to other Protein supplements).

Cannabis

Cannabis is the common name and genus for a few plants used around the world due to their psychoactive properties. Its major component, known as THC, possesses acute benefits but is subject to rapid tolerance. Additionally, nonpsychoactive components like CBD may have chronic benefits. While therapeutic, particularly for pain relief, the plant is not a panacea.

Our evidence-based analysis on cannabis features 814 unique references to scientific papers.

This page is regularly updated, to include the most recently available clinical trial evidence.

Each member of our research team is required to have no conflicts of interest, including with supplement manufacturers, food companies, and industry funders. The team includes nutrition researchers, registered dietitians, physicians, and pharmacists. We have a strict editorial process.

This page features 814 references. All factual claims are followed by specifically-applicable references. Click here to see the full set of references for this page.

Kamal Patel

Primary information, health benefits, side effects, usage, and other important details

Cannabis is the common name for a few plants in the cannabis genus, including sativa, indica, and ruderalis. It is primarily used for its psychoactive properties around the world. Cannabis has also been traditionally used to treat inflammatory disorders and is increasingly being used in modern medicine.

Cannabis’ primary active chemical, Δ 9 THC, or delta-9 tetrahydrocannabinol, acts on the cannabinergic system in the body, which is actually named cannabis after the plant. This system is regulated by two receptors, called cannabinoid receptor type 1 (CB1) and cannabinoid receptor type 2 (CB2). CB1 is responsible for most of the psychoactive effects of cannabis, and CB2 is responsible for many of the long-term benefits cannabis may provide for inflammation and related diseases.

THC and CBD appear to be notable analgesics and can reduce pain in a variety of health conditions. Pain in multiple sclerosis and neuropathic pain, in general, have the best evidence for benefits, and they also appear to be useful in cancer, fibromyalgia, rheumatoid arthritis, and pain from wounds. However, more research on those is needed. There is great interest in using cannabis to reduce opioid use, and while some evidence supports this, more research is needed to determine where it may be most effective. In instances of severe pain, the reduction in pain may not be enough to reduce opioid use.

Inhaling cannabis smoke increases diastolic blood pressure and heart rate, though this change is temporary. However, many case studies note cannabis usage 30 – 60 minutes before heart attacks, so it’s possible that this acute effect could be dangerous for those at high risk. Heart attacks can occur when people with an elevated risk for heart disease push their blood pressure and heart rate to dangerous levels. It may also interact with some pharmaceuticals, which could result in elevated blood pressure and a heart attack. Smoking cannabis has also been associated with bronchitis.

Cannabis usage over a long period of time can cause tolerance and subsequently withdrawal. Cannabis withdrawal is recognized by the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). On a molecular level, cannabis tolerance occurs when the CB1 receptor is overstimulated and internalized, meaning absorbed by the cell. The CB1 receptor and the N-methyl-D-aspartate receptor (NMDA) receptor are linked when it comes to cannabis, so when CB1 signaling is inhibited, NMDA signaling is also hampered. This may cause cannabis to be less effective for treating epilepsy and schizophrenia, though it also reduces the memory loss associated with cannabis use. Tolerance does not significantly affect the CB2 receptor, so cannabis may be effective for inflammatory disorders over a longer period of time.

Note:

Originally, this page included various studies on isolated THC. We have decided to transition the Human Effect Matrix of this page to one that exclusively includes studies on combinations of THC and CBD, either in the form of whole cannabis leaf, cannabis oil, or pharmaceutical combinations of THC and CBD. We have a dedicated CBD page and hope to release a dedicated THC page in the not-too-distant future.

In one sense, this should provide us a better way to understand the expected effects of different products. On the other hand, because a large amount of clinical research is in isolated and synthetic THC, this page by itself is insufficient, in a sense. Various painful conditions that respond to isolated THC could also benefit the same dose of THC from whole cannabis or a THC/CBD product, as the addition of CBD or the other parts of cannabis will be unlikely to counteract those effects; if anything CBD appears to be a notable analgesic in its own right. So when you’re using this page, know that there’s a good chance that there is more research on isolated THC or CBD for various outcomes (especially chemotherapy side-effects).

This page is also incomplete because we have omitted some research that we didn’t find to be particularly useful for this page. This included a vast literature on the psychological and cognitive effects of cannabis, largely when taken acutely. It also included various studies on health conditions where there were very few applicable studies, though these will be added next update.

Cannabis is the common name and genus for a few plants used around the world due to their psychoactive properties. Its major component, known as THC, possesses acute benefits but is subject to rapid tolerance. Additionally, nonpsychoactive components like CBD may have chronic benefits. While therapeutic, particularly for pain relief, the plant is not a panacea.