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CBD vs Ibuprofen for Managing Pain

Ibuprofen is one of the go-to medications for pain relief. However, there is growing interest in the potential of cannabidiol as an alternative. We’re taking a look at the available research to see how CBD performs in terms of dealing with pain. Let’s dive in.

Conventional medicine will tell you that ibuprofen is one of the most effective means of treating pain. Since the 1960s [1] , it’s been the go-to medication for run-of-the-mill malaises like headaches, toothaches, and back pain.

On the flip side, you have cannabidiol, a promising compound from the cannabis plant. CBD, as it’s most commonly known, has been a subject of study for several conditions, including pain. But, unlike ibuprofen, it does not have approval from medical experts yet.

Regardless, CBD remains in conversation as a natural, versatile compound with intriguing effects. But, how effective is it really? This article aims to answer that question.

Contents:

How Ibuprofen Works

Ibuprofen is one of the most common forms of nonsteroidal anti-inflammatory drugs (NSAIDs). Additionally, it is effective in eliminating fever and headaches.

Ibuprofen works by reducing the hormones that cause both pain and swelling. It inhibits the release of prostaglandins [2] , chemical compounds responsible for controlling inflammation and blood flow.

Ibuprofen specifically targets the COX-1 and COX-2 enzymes by decreasing their activity. These two enzymes trigger inflammation and fever [3] .

But, when it comes to benefits, ibuprofen goes beyond just pain control. It’s proven to be effective against rheumatoid arthritis and diseases, minor musculoskeletal injuries, and fever, and it also helps prevent the formation of blood clots.

CBD vs Ibuprofen

We now have a general idea of how ibuprofen works. So, let’s shift our attention to CBD and how it operates in the body.

CBD primarily interfaces with the body via the endocannabinoid system. It doesn’t bind directly to innate receptors in this system (CB1 and CB2), but it can enhance natural endocannabinoid levels and benefit the system in other ways [4] . The ECS is responsible for regulating several major functions, including sleep, pain, immune system response, and appetite. Thus, any compound capable of boosting this system’s efficacy is deemed worthy of exploration.

But, if ibuprofen is so effective, why would we even be courting CBD for its potential? Well, because taking ibuprofen carries several risk factors that are definitely worth taking into account. According to the FDA, NSAIDs including ibuprofen may increase the risk of heart attacks and strokes, even with short-term use [5] . Symptoms may arise within a few weeks.

Ibuprofen is derived from propionic acid, the same fatty acid present in processed food. It is primarily used to fight off mould and bacteria, and may severely irritate the skin upon direct interaction. However, the FDA deemed it to have little toxicity [6] in humans.

As for CBD, it is extracted from the hemp plant with the help of a solvent like ethanol or carbon dioxide. The cannabidiol is then transformed into oil, topical, or capsule gel form for consumption.

CBD vs Ibuprofen

Can You Take CBD and Ibuprofen Together?

On the one hand, you have a fast-acting synthetic drug with known side effects and health risks. On the other, you have an organic substance that’s perceived to have its own benefits—without the risks [7] . Looking at it on paper, combining the two isn’t such a bad idea.

And it may not be. This 2019 study [8] , for one, reports no direct interactions between ibuprofen and CBD. However, that isn’t the case with other NSAIDs like naproxen and celecoxib. Experts advise against the co-administration of cannabidiol and these aforementioned drugs.

The likelihood of side effects may vary between individuals. Your best bet here would be to consult your doctor before taking CBD alongside ibuprofen.

Is CBD a better alternative to ibuprofen when it comes to managing pain? Or will it only worsen the situation? Read on to find out.