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500mg cbd oil for dogs

VetCS CBD Oil for Small Breed Dogs 500mg CBD, 15ml

This product is best for small breed dogs (less than 20 lbs) or cats, for a 30-60 day supply. We use a full size bottle for this size, so that we can use our wonderful measuring dropper! This bottle will arrive half-full.

Curious if CBD is right for your pet? Call our veterinary team at 1-800-840-5730 or email us at [email protected] We would love to help you build the best wellness plan for your pet!

Safety:

Our full spectrum CBD extract oil is produced in facilities compliant at the FDA level; we want to assure your pet is receiving the same amount in every dose, and every bottle. We have set the stage for transparency standards that is unheard of in the veterinary cannabis industry.

Dosing:

Dosing information: Refer to Dosing chart. Tincture can be given directly in the mouth or with food. It should be given twice daily to maximize efficacy. Effects can be seen within 3-5 days. Loading doses should be maintained for 1 week, then decreased to half doses twice daily. For added support, week 1 doses can be maintained long term if needed. Note: Cats do not like the odor of this hemp extract, we advise using our low scent CBD oil.

Certificates of Analysis:

**Note: It is typical for cannabinoid potency levels to vary between 4-6 mg/ml based on batch and lab testing variance, higher concentrations of cannabinoids are considered safe as long as THC is below 0.3%.**

CBD Oil for small dogs with full spectrum hemp for best efficacy for calming, supporting wellness, and mobility disorders. Easy to dose based on our chart and comes in two flavors: Bacon or Full Plant. Lasts 30-60 days for most small dogs. Our Veterinary Team is standing by to answer questions!

500mg CBD Oil for Medium to Large Dogs

Max and Neo CBD’s 500mg CBD Oil is a pure full spectrum organic hemp oil extract made from top grade hemp from Colorado, USA. The 500mg bottle is great for medium and large sized dogs.

Using the complete plant profile during our extraction process we produce a full-spectrum oil, containing all the beneficial properties naturally found in hemp.

Our CBD oil is unflavored as it is mixed with MCT oil. The oil can be given directly to the dog or placed on its food.

This bottle will last approximately 100-200 days for dogs between 25 to 50 lbs using recommended dosage once per day.

Ingredients:
MCT Oil, Hemp Seed Oil, Full Spectrum Hemp Oil Extract

Serving Size: 20 drops (0.5ml)
Servings Per Bottle: 50

Amount Per Serving:
Full Spectrum Hemp Oil Extract 10 mg (.5 mg per drop)

Start with a lower dosage and gradually increase to the recommended use.

Recommended Use

.5 mg Full Spectrum Hemp Oil Extract per drop

1-5 drops – dogs up to 25 lbs
6-10 drops – dogs 25 to 50 lbs
11-15 drops – dogs 50 to 75 lbs
16-20 drops – dogs 75 to 100 lbs

The general recommended dosage is about 1mg of Full Spectrum Hemp Oil Extract per 10 pounds of dog weight. Adjust up or down depending on results.

Max and Neo CBD's 500mg CBD Oil is a pure full spectrum organic hemp oil extract made from top grade hemp from Colorado, USA. The 500mg bottle is great for medium and large sized dogs. Using the complete plant profile during our extraction process we produce a full-spectrum oil, containing all the beneficial properties

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how to take cbd oil sublingually

How to Take CBD Oil: Ingestion, Sublingual, Topical and Inhalation Options

With more research discovering new potential wellness and therapeutic applications for cannabidiol ( CBD ), the demand and availability of CBD products continues to increase. The greater variety of products gives patients more choices to find a CBD option and method of consumption that aligns with their health and lifestyle needs.

In general, there are four primary methods for taking CBD oil to choose from:

  • Ingestion
  • Sublingual
  • Topical
  • Inhalation

Here we explore each of those four methods and discuss the advantages of each so that you can select a product that’s best for you or your family member.

Ingestion Options

Perhaps the most common way to take CBD oil is to ingest it orally. When you ingest CBD oil, it passes through the digestive system and is metabolized by the liver, eventually sending its active compounds to your bloodstream. This form of administration is exactly how vitamins and other daily supplements are most typically taken.

Common ingestible CBD oil products include capsules , edibles, and beverages. Capsules can be easily swished down with a mouthful of water and are among the most efficient ways to take CBD. CBD oil can be infused into a wide variety of edibles and beverages, including coffee.

Sublingual Options

When CBD oil is administered sublingually, it’s held under the tongue for up to 90 seconds so that the mucus membranes in the mouth can absorb the oil’s active ingredients. The benefit of consuming CBD oil sublingually is that the absorption process bypasses the digestive system and liver metabolization, allowing the compounds to reach your bloodstream and interact with the endocannabinoid system more quickly. For those looking for quick effects, a sublingual CBD oil product is ideal.

Pure CBD oil, as well as tinctures and concentrates, are CBD products that are designed for the sublingual method of application. They can easily be held in the mouth to give the active ingredients time to be absorbed by the capillaries in the mouth before being swallowed.

Topical Options

Some CBD oil products are designed to be applied directly onto the skin. The active ingredients in these topical CBD products are absorbed through the skin so that they can interact with cells that are nearby the surface without ever entering the bloodstream. Topical CBD oil products are ideal for those looking for isolated pain relief or to address skin conditions because they can be applied directly to where they are needed most.

The CBD oil topical products currently on the market primarily include lotions and salves. These products are more applicable for potentially addressing pain or serious skin issues . For daily skin health care, some companies also produce a collection of CBD oil bath and body care products, such as body wash, shampoo, conditioner, and moisturizing lotions.

Inhalation Options

Finally, CBD can also be inhaled by vaporizing. A vaporizer heats CBD oil just enough to release its active compounds, avoiding the harmful byproducts that are created with combustion. During vaporization, CBD enters your lungs and diffuses directly into your bloodstream. Because it doesn’t have to make its way through the digestive system or liver, the CBD enters your circulation faster. Also, less CBD is lost during vaporizing compared to the ingestion method. Vaporizing CBD is typically a consumption option recommended for adults.

CBD oil products designed for vaporization include CBD e-liquid, which contains CBD oil infused with vegetable glycerin (VG), or high-CBD concentrate. Vaporizers range in size from tabletop, plug-in powered units to small, battery-powered portable pens.

Here we explore each of the four common methods for consuming CBD and discuss the advantages of each so you can find the product that's right for you.

How to Take CBD Oil Sublingually

Green Roads CBD oil

For recreational users, smoking and vaping are the preferred methods of consuming cannabis or CBD products. These methods allow cannabinoids to rush directly to the lungs. Smoking and vaping are very efficient methods and can increase bioavailability to 50% or above. Bioavailability determines the percentage of drugs or substances that becomes available to the target tissue after administration. This means that up to 50% of the cannabis content that you inhale when you smoke or vape is available for your body. In contrast, CBD edibles fall between 4-20% bioavailability rate.

However, smoking, and vaping are not everybody’s cup of tea. Some just don’t like the idea of smoking or vaping in general. There are also those who find it inconvenient since it limits their use to their homes. Although vaping, and smoking equipment are portable, some areas prohibit smoking and vaping in public places; both indoors and outdoors. In addition, there are also those with existing lung conditions who cannot smoke or vape.

Sublingually taking CBD oil is a convenient alternative to smoking or vaping. The word sublingual means under the tongue. In this method, the user applies a few drops of CBD oil or cannabis tincture under the tongue. This method is different from directly swallowing the tincture or oil.

What are the advantages of taking CBD Oil sublingually?

Better Bioavailability. Most users who take CBD oil sublingually experience the health benefits of CBD oil within 20 minutes?. This makes it the perfect method for those who use CBD products for pain relief of chronic pain. Those who suffer from neuropathic pain caused by arthritis will also benefit from the fast relief brought about by sublingually taking CBD oil. Arthritis-related pain can flare up any moment and although you can relieve it by using other CBD products, CBD oil through sublingual delivery is still the best method to deliver immediate relief.

Why is the effect so fast? This might be due to the fact that you’re not digesting the oil. Sublingual products don’t go through the digestive tract. When you swallow a CBD edible or capsules, it goes through your digestive system and it needs to undergo digestion before you can feel its effect. In contrast, CBD oil or cannabis tincture taken sublingually gets absorbed directly into the bloodstream. The increased bioavailability can also be attributed to the fact that sublingual consumption of CBD Oil bypasses the first-pass effect in the liver which happens when you digest edibles.

It is a discreet method. You can sublingually take CBD oil in a very discreet manner. Unlike smoking or vaping CBD, you can do it in a quiet corner without anybody noticing. It doesn’t emit any smoke or smell that can draw attention to one’s self. This method also doesn’t require any prep work on the user’s end. The dropper bottles used in this method are very small and you can easily conceal them in your purse or even your pocket. Although a vaporizer and a bottle of vape oil is easy to conceal, a bottle of CBD oil is still smaller in comparison

How do I take CBD oil sublingually?

Taking CBD Oil sublingually is a pretty straightforward process. You just need to use the dropper that usually comes with the CBD Oil to take a few drops of CBD. Put a few drops of your preferred CBD Oil under your tongue. You need to hold the oil under your tongue for at least a minute or two. This will ensure that the oil gets absorbed through your sublingual tissues so it can enter your bloodstream. You can then swallow any excess oil left behind.

Some users who take CBD Oil sublingually take an extra step before swallowing the oil. You can also swish the remaining oil around your mouth. This will distribute the oil to your cheek tissues or even into your gums. This method of taking CBD Oil through the cheek tissues is called Buccal. If you’ve tried oil-pulling before then this is something similar.

Although this is not a requirement, it increases the contact between the oil and the capillaries in your mouth. This means you also increase the chances of getting as much CBD oil to your bloodstream as possible. If there is still oil left after swishing the oil around your mouth, then you can just swallow the rest.

What kind of carrier oil is best for taking CBD oil sublingually?

Pure CBD oil by itself is easily absorbed by the human body. However, its absorbency by the body gets improved when you use it with a carrier oil. Hemp oil products like THC and CBD from the cannabis plant are fat-soluble. This means that they increase their bioavailability when you infuse them in saturated fat.

Hemp Seed Oil. Despite its name, Hemp Seed Oil doesn’t contain cannabinoids. Hemp seed oil is a product derived by cold-pressing hemp seeds and not the hemp plant. What’s great about hemp seed oil is it contains a unique 3:1 essential fatty acids ratio. Hemp seed oil is also tastier. It has a slightly nutty flavor which makes it more tolerable if you intend to take CBD oil sublingually.

Olive Oil. Olive oil is a very popular cooking ingredient. People drizzle it over salads, use in making pasta, or as a dip for pieces of bread. It has a vegetable flavor and is ideal for those who like the taste of Olive Oil. Olive Oil also contains LCTs or long-chain triglycerides. LCT translates into higher bioavailability compared to medium-chain triglycerides (MCTs) which makes it more efficient as a carrier oil.

Coconut Oil. This MCT oil has long been acknowledged for its health benefits. This is the perfect carrier oil for those who have heart conditions because coconut oil has high lipid content. The saturated fat content of coconut oil won’t clog up your arteries.

How much CBD Oil should I use?

This is a question that many have asked. Unfortunately, there is no definite answer. The Food and Drug Administration (FDA) is the government arm responsible for providing a Recommended Daily Intake (RDI) but they haven’t released an official RDI for daily CBD servings. If you don’t know what RDI is, it is the daily levels of a nutrient that meets the requirements of 97-98 percent of individuals in the United States. You usually find RDI information on any supplement you purchase.

So, how do you formulate a dosage for CBD oil? Treat CBD as you would any new supplement that you might take. Start with small doses. This way, you completely avoid going over the level that might be too much for you. Remember that it can take up to an hour for you to feel the effects of CBD oil taken sublingually so you need to be patient and wait for the effects to your body. Once you’ve felt the effects and they are not enough for you, then you can gradually increase the dosage of the following intake.

If you know someone else who takes CBD oil sublingually, do not assume that the dosage that works for them will also work for you. The effects of CBD are different for each individual. In the absence of an FDA RDI, it will be best to determine on your own the right dosage based on what works for you.

Another thing to take note of is the potency of the CBD oil that you’re taking. Different oils have different potencies. If you decide to switch to another CBD oil then you need to take potency into consideration. If you switch to a more potent oil, lower the dosage you are taking and then gradually increase it. If you’re switching to a less potent oil, go with the same dosage you’re previously using and work your way up.

This is not an exact science yet. However, until the FDA comes up with an RDI for cannabis products, these are sensible and the safest you can get.

Genetics and CBD Dosages

Genetics also play a huge role in how a user decides on an appropriate dosage. Some users have mutations on their CNR1 gene. If you have an issue with your CNR1 gene, it can result in a poorly functioning endocannabinoid system. For example, THC can increase the activity of CB1 receptors. On the other hand, alcohol can increase its expression. This means that smoking cannabis and drinking alcohol can increase the effects of CBD because of their interaction with cannabinoid receptors.

Can I overdose on CBD oil if I take it sublingually?

As of this writing, authorities haven’t determined yet a lethal dose of CBD. Even doses of up to 1500 mg per day are safe for humans?. However, it is also important to consult with your physician before taking CBD oil sublingually, or through any other method for that matter. However, there are still some slight risks associated with the use of CBD in high doses or for extended periods. These include:

  • Mild Low Blood Pressure
  • Dry Mouth
  • Lightheadedness
  • Sluggishness

These side effects are possible on worst case scenarios. The use of CBD and other hemp products are still safe.

Sublingual CBD oil provides greater bioavailability than most other methods of consumption. Place a few drops underneath your tongue to feel the effects.

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is cbd oil legal in mississippi 2021

CBD Legal States 2021

CBD (cannabidiol) is a non-psychoactive compound found in cannabis. Unlike tetrahydrocannabinol (THC), CBD does not get a user “high;” however, its legality is still a gray area for some people because it is derived from the cannabis plant.

Is CBD Legal in the U.S.?

CBD must be legal on both the federal level and the state level in order for it to be legal in your state.

The 2018 Farm Bill legalized, on the federal level, the regulated production of hemp, or any part of the cannabis plant with a THC concentration below 0.3%. States, however, have the final say in whether or not cannabis-derived products are legal within their state lines.

Is CBD Legal in my State?

Marijuana legality varies by state, as does CBD legality.

There are 17 states called that legalized both medicinal and recreational use of marijuana as long as you meet the minimum age requirement.

  • Alaska
  • Arizona
  • California
  • Colorado
  • Illinois
  • Maine
  • Massachusetts
  • Michigan
  • Montana
  • Nevada
  • New Jersey
  • Oregon
  • South Dakota
  • Vermont
  • Virginia
  • Washington
  • Washington D.C.

In addition to these states, sever other states have legalized medical marijuana:

  • Arkansas
  • Connecticut
  • Delaware
  • Florida
  • Hawaii
  • Kansas
  • Louisiana
  • Maryland
  • Minnesota
  • Mississippi
  • Missouri
  • New Hampshire
  • New Mexico
  • New York
  • North Dakota
  • Ohio
  • Oklahoma
  • Texas
  • Utah
  • West Virginia

The following states have legalized CBD, some only for specific medical purposes:

  • Alabama
  • Georgia
  • Idaho
  • Indiana
  • Iowa
  • Kentucky
  • South Carolina
  • Tennessee
  • Wisconsin
  • Wyoming

Some of these states only allow CBD below certain THC levels. CBD and CBD products in Idaho are legal only if they contain zero THC and are derived from the mature stalks of the plant. In Tennessee, possession of CBD products is legal if they contain less than 0.6% THC. In Alabama, the maximum THC level is 0.3%.

CBD Legal States 2021 CBD (cannabidiol) is a non-psychoactive compound found in cannabis. Unlike tetrahydrocannabinol (THC), CBD does not get a user “high;” however, its legality is still a gray

Mississippi

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Contents

  1. Is weed legal in Mississippi?
  2. Legislation history
  3. Where is it safe to purchase weed in Mississippi?
  4. Where is it safe to consume cannabis?
  5. Medical Marijuana in Mississippi
  6. Frequently asked questions

Is weed legal in Mississippi?

Medical marijuana will be legal in Mississippi in 2021. Cannabis for recreational use remains illegal. CBD oil with at least 15% CBD and no more than 0.5% THC is legal for patients with debilitating epilepsy.

Cannabis is decriminalized statewide. Possession of up to 30 grams (1 ounce) of cannabis or 10 grams of synthetic cannabinoids is punishable by a fine of $100 to $250 for the first offense. Subsequent offenses and possession of larger amounts carry greater penalties.

Legislation history

In 2014 Gov. Phil Bryant signed HB 1231 , or “Harper Grace’s Law,” named after Harper Grace Durval, a young girl with a severe form of epilepsy. The law provides an affirmative defense to patients who suffer from a debilitating epileptic condition and their parents or guardians for the possession and use of CBD oil or resin that contains at least 15% CBD, or if in liquid form at least 50 milligrams of CBD per milliliter, and no more than 0.5% THC.

CBD oil may only be procured by order of a doctor licensed to practice in Mississippi, and administered under the supervision of the physician. Only patients diagnosed with epilepsy or a related illness, or their parent or guardian, can buy or possess CBD oil.

Mississippians approved Initiative 65 in the November 2020 election, which legalizes the use of cannabis as a medical treatment for 22 qualifying conditions. Patients will be allowed to possess up to 2.5 ounces of cannabis. It set up a process for physicians to recommend medical marijuana for patients with debilitating conditions and allow those patients or their caregivers to purchase, possess, and consume cannabis medicine.

The measure also required the Department of Health to set up the system and begin issuing patient ID cards and dispensaries licenses by August 2021. The state legislature had put forth an alternative proposal, Initiative 65A , leaving all the details up to an unnamed state agency while requiring it to seek the input of health-care practitioners in the program design. Voters chose the more direct path to medical marijuana legalization.

Where is it safe to purchase weed in Mississippi?

CBD oil may only be obtained from the University of Mississippi Medical Center’s Department of Pharmacy Services.

Where is it safe to consume cannabis?

Qualified patients may consume approved cannabis-derived medicines in their home. Consumption in public is prohibited.

Medical Marijuana in Mississippi

Qualifying Conditions

The only qualifying condition in Mississippi is debilitating epilepsy or related conditions.

Frequently asked questions

What are the laws on possession of small amounts of marijuana in Mississippi?

Small amounts of marijuana have been decriminalized in Mississippi since the 1970s. Possession of up to 30 grams (1 ounce) of cannabis or 10 grams of synthetic cannabinoids is punishable by a fine of $100 to $250 for the first offense. Subsequent offenses and possession of larger amounts carry greater penalties.

When will marijuana be legal in Mississippi?

While we can’t predict the future, we know that Mississippians can petition to have a vote on recreational cannabis legalization added to the ballot. Usually states legalize medical marijuana first, which is also true in Mississippi’s case. Mississippians approved Initiative 65 in the November 2020 election, which legalizes the use of cannabis as a medical treatment for 22 qualifying conditions. Patients will be allowed to possess up to 2.5 ounces of cannabis. The Mississippi Department of Health must adopt all rules and regulations for the medical program by July 1, 2021, and begin issuing identification cards and treatment center licenses by August 15, 2021 .

This page was last updated November 4, 2020.

View the cannabis & CBD laws & regulations for Mississippi.

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is cbd oil legal in missouri 2021

Where to Buy CBD in Missouri in 2021

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If you’re looking to buy CBD in Missouri, placing your order through a trustworthy online store is usually your best bet.

CBD is gaining momentum across the United States. The laws regarding cannabis extracts vary quite a bit from state to state and largely depend on how they’re manufactured.

This article will clear up any concerns you might have about purchasing CBD in Missouri and show you the best places to buy online and in-store.

Before you place an order, it’s good to know a little bit about CBD and why everyone is trying to get some for themselves.

Table of Contents
  • Buy CBD Oil in Missouri:
  • What is CBD?
  • Is CBD Legal in Missouri?
  • How to Buy High-Quality CBD in Missouri
  • Where Can I Buy CBD in Missouri?
    • Buy CBD Oil Online
  • Is Marijuana Legal in Missouri?
    • Medical Marijuana
    • Recreational Marijuana
  • Recommended CBD Retailers in Missouri
    • St Louis
    • Kansas City
    • Springfield
  • Final Notes on Buying CBD in Missouri

Buy CBD Oil in Missouri:

  • Royal CBD Oil— Best CBD Oil Overall
  • Gold Bee CBD Gummies— Best CBD Gummies
  • CBDistillery THC-Free Pure CBD Oil— Best CBD Isolate Oil
  • Industrial Hemp Farms— Best CBD Flower
  • Honest Paws CBD Oil For Dogs— Best CBD Oil For Dogs

What is CBD?

CBD (cannabidiol) is a non-psychoactive chemical compound found in cannabis plants. Non-psychoactive means that it doesn’t produce the high that is usually associated with marijuana.

It is useful for treating the symptoms of many conditions, including cancer, HIV, glaucoma, epilepsy, post-traumatic stress disorder, and many others.

The chemical that causes the high associated with cannabis is called THC and is found primarily in flowering marijuana plants. Industrial hemp plants do contain a small amount of THC; however, it’s generally not enough to get you high.

CBD can be made from both marijuana and industrial hemp plants. The law in Missouri treats the two differently.

Let’s take a look at the marijuana laws in Missouri.

Is CBD Legal in Missouri?

Despite Missouri’s harsh marijuana laws, it’s possible to purchase legal CBD.

As we discussed before, CBD can be sourced from both flowering marijuana plants and industrial hemp plants.

Flowering marijuana plants produce CBD with high THC content and are illegal in Missouri. Missouri law treats this CBD the same as smokable marijuana. Avoid this, and you’ll avoid trouble with the law.

If your CBD is produced from industrial hemp plants, it will usually contain less than 0.3% THC.

Industrial hemp CBD is legal to purchase and possess under the federal Farm Bill of 2014, which removed industrial hemp from the Controlled Substances Act and allowed farmers to produce hemp for research and commercial purposes.

Some of the most common uses of industrial hemp are for fuel, food, and clothing.

Luckily for those of you looking for CBD in Missouri, industrial hemp can also be used to produce products rich in CBD.

Using these products, you can get relief from pain, inflammation, seizures, nausea, and more without worrying about the police.

You can usually find industrial hemp CBD over the counter in Missouri.

It’s essential that you research the products before you purchase because there are a ton of companies that are capitalizing on uninformed customers and selling products that contain almost no CBD.

We have included a few tips for buying the right CBD product for your needs and protecting yourself from these shady companies.

Take a look at our guide below to make sure you get high-quality CBD every time!

How to Buy High-Quality CBD in Missouri

Taking the time to research the background of CBD companies will save you time and money.

If you’re looking to get the best CBD products for your needs, follow these steps to avoid the fakes.

  1. Only order from companies that get their products tested by an outside lab. These labs can check the CBD for any unwanted additives, including heavy metals and solvents. They will also make sure that the CBD content matches what’s on the packaging. Don’t waste your time if the company hasn’t had its products tested.
  2. Buy CBD that has been extracted using CO2; this is by far the best method for extracting CBD. It doesn’t require any heat or additional solvents, so it keeps the CBD as pure as possible. The machinery needed to perform CO2 extraction is quite expensive as well. Therefore, any company using this method likely takes its business seriously and is committed to a quality product.
  3. Double-check the THC content. This is especially important in Missouri, where CBD with high THC content is illegal. Don’t get busted for possession with marijuana-derived CBD. Industrial hemp CBD, on the other hand, offers many of the same health benefits without the high and risk of getting into trouble.
  4. Use full-spectrum CBD products to get the maximum benefits. Full-spectrum CBD products contain additional useful compounds, including terpenes and flavonoids. This type of CBD is also generally more difficult to extract, which is a good sign that the company is committed to a quality product.

These steps will weed out a lot of the sketchy companies and put you on the path to a reliable supplier for all of your CBD needs.

Now for the exciting part: where do you buy industrial hemp CBD in Missouri?

Where Can I Buy CBD in Missouri?

Industrial hemp CBD can be found easily online or in stores across the state.

As a general rule, it’s most convenient to order your CBD from an online store.

However, if going to a local spot is more your style, check out our list below of great places to try in Missouri.

Buy CBD Oil Online

Shopping online for your CBD has several benefits, including convenience and cost.

Online retailers will almost always have a better selection than what you would find in-store. Without the need of keeping a physical storefront stocked all the time, online retailers can have a wider variety of products available to ship at any time.

Another pro that comes from not needing a physical store is that products found online are less expensive. Rent is not cheap, and the prices in-store often reflect that. You can save yourself money and get higher-quality products by shopping online.

Are you running low on CBD at midnight while in your pajamas? No worries. You can place your order at any time when you purchase online — no need to get dressed and hurry off to the local shop before it closes.

However, we understand that sometimes going into a store, and holding the product for yourself makes a big difference. If you would prefer to shop local, see if you can find your city on our list below!

Is Marijuana Legal in Missouri?

Missouri laws don’t mess around when it comes to marijuana. Even small infractions can carry harsh penalties.

Your first offense of possession under 10 grams will get you a fine of up to $500 with no time in jail. On your second offense, however, jail time gets added. It is considered a misdemeanor, and you can receive up to a year in prison.

If you possess more than 10 grams, that’s considered a Class A misdemeanor and will get you up to a year in jail and a $1000 fine.

Missouri takes the sale of marijuana especially seriously.

The sale of fewer than 5 grams is a felony with a maximum punishment of up to 7 years in prison and a $5000 fine. More than 5 grams can land you in jail for 5 to 15 years and a $20,000 fine.

Not all is lost. Missouri’s medical marijuana program is slowly starting to operate.

Medical Marijuana

On November 6th, 2018, Missouri voters passed Amendment 2, which legalized medical marijuana.

Under Amendment 2, medical marijuana sales will be taxed at 4%, which will be used to support military veteran services. This tax is estimated to generate approximately $24 million per year.

Unlike many other states’ medical marijuana programs, there are no necessary qualifying medical conditions. A patient only requires a doctor’s recommendation to get medical marijuana as a treatment.

Once you have been approved for the Missouri medical marijuana program, you’ll be able to grow up to six plants at home and purchase up to four ounces per month from dispensaries.

On August 10, 2019, the Missouri Medical Marijuana program started accepting applications. Although the number of applicants who have decided to pay their fees beforehand has come to 600, the number of full applications is only 27.

However, the numbers shouldn’t worry you because the state’s program is not complete. There is more license work to be done. Medical marijuana is not expected to start operating in Missouri before the spring of 2020.

Recreational Marijuana

Recreational marijuana use is illegal in all circumstances. There are currently no plans to start a recreational marijuana program in Missouri.

So far, only ten states have legalized marijuana for recreational use — and most of them are out west. Marijuana is illegal for recreational use in every mid-west state, except Michigan.

How does CBD fit into all this?

Recommended CBD Retailers in Missouri

St Louis

  1. The No Smoke Shop
  2. Mape Vape
  3. Lemay Vapor
  4. CBD KRATOM
  5. The Cave Smoke Shop

Kansas City

  1. Let’s Smoke & Vape Shop
  2. KC Smoke and Vape
  3. CBD Plus
  4. KC SmokZ
  5. Smoke Tokz Vape Shop

Springfield

  1. CBD of Springfield
  2. Titan Vapors
  3. Vapor World Kearney
  4. Electric Puff Vapor Shop
  5. Cosmic Fish
  6. Palm Beach Vapors

All of these stores should have helpful and knowledgeable employees who can recommend the right CBD product for your needs.

If you can’t find CBD locally, make sure you take a look online.

Regardless of where you find your CBD, always do your research before you buy.

Final Notes on Buying CBD in Missouri

Missouri has strict marijuana laws. However, don’t let them stop you from finding a reputable CBD supplier!

Marijuana-derived CBD high in THC is illegal to purchase and possess in Missouri. If you’re caught with these extracts, the police will treat you no differently than if you had actual marijuana.

Industrial hemp CBD, on the other hand, is legal to possess in all 50 states. It’s a great way to boost your overall health and find relief from several medical conditions.

The best way to purchase legal CBD in Missouri is by ordering from an online retailer. Otherwise, head down to your local vape shop and see what it has to offer in-store!

Are you looking for CBD in Missouri? This article will clear up the laws & point you in the direction of a reliable CBD supplier in Missouri.

CBD Oil Missouri: Is Cbd Legal In Missouri & Where To Buy?

Missouri state

More and more Americans are using CBD to either improve their well-being or general health. The plant-based CBD has powerful treatment capabilities for specific conditions like depression, anxiety, epilepsy, insomnia, among others. It also improves the digestive system, skin, and organ health.

Missouri has the most significant number of CBD retailers in the United States and a rapid influx of vape shops around the state selling CBD products. However, Missouri CBD users are confronted with a seemingly complex contradictory legal framework as they try to find out whether or not use, and ownership of CBD is allowed in Missouri under state and federal law.

Is CBD Legal in Missouri?

Missouri was the 2 nd largest hemp producer behind Kentucky. Hemp cultivation in Missouri State can be traced back to 1835. In 1844, Missouri hemp farmers produced 12,500 tons of hemp.

However, back then, hemp was more labor-intensive than other crops, had less profit, and without slave labor by the end of the Civil war, hemp production had dropped off significantly.

In the 1930s, the “Reefer Madness” mentality was promoted by the US federal government to demonize cannabis, it lasted for decades, and Is still prevalent today. However, near the end of the 20 th century, states started to defy federal law by legalizing the use of weed for medicinal purposes, and things began to change.

However, it wasn’t until 2014 that Missouri started to catch on. At the time, the US government considered marijuana and hemp the same plant. Missouri lawmakers then created the Missouri Hemp Extract Registration Program in the same year to allow the use of low-THC hemp extract in treating intractable epilepsy and approving patients to purchase low-THC hemp extracts from ‘cannabidiol oil care centers’ regulated by the state.

The federal government also passed legislation at the end of 2014 that permitted state universities to implement hemp pilot programs to study further the processing and cultivation of hemp, which helped speed up the process.

The Missouri General Assembly then passed a measure in 2018 to remove hemp from marijuana definition. The Industrial Hemp Research Program was created to leverage the 2014 law, and universities in Missouri were allowed to plant hemp for a research basis, starting with the 2019 growing season.

The federal government then went a step further to legalize the commercial cultivation as well as the sale of hemp at the end of 2018. In July 2019, a bill was signed into law that made Missouri the 32 nd state to legalize medical marijuana. With time, Missouri might legalize marijuana as well, with ten marijuana legalization petitions being circulated to be added into the 2020 ballot.

To legally use CBD oil in Missouri, you should be approved by the MHERP to participate as a patient. Patients eligible to participate in this program are those diagnosed with intractable epilepsy.

Since August 3, 2019, Missouri started accepting licensed dispensary facility applications; hence patients or licensed caregivers can legally obtain and possess cannabis. However, the Missouri medical laws, patience below 18 years should have the consent of the parent or guardian to apply for a registration card, certified by their physician.

At the cost of $25, medical use and caregiver identification cards are available via the DHSS website. With the cards, purchases are restricted to state-licensed dispensaries. However, the use and possession of marijuana for recreational purposes is illegal in Missouri.

It is also illegal to consume marijuana in public spaces open to the general public like streets, sidewalks, businesses, schools, and parks. However, the state’s hemp laws don’t specify whether the use and possession of CBD oil are legal.

It seems like the Missouri law enforcement agencies have no interest in indicting those in possession of hemp-derived CBD because there are countless shops in the state that are already selling hemp CBD oil regardless of the gray areas in the law regarding CBD.

There are two sets of marijuana laws in Missouri – those concerning medical marijuana patients and everyone else. Medical marijuana patients are allowed to purchase CBD oil products with their cards at state-licensed dispensaries.

Why You Should Buy CBD Oil Online

Ordering CBD oil products online has many advantages. For instance, you will have a much wider range of online retailers to choose from. You will also experience the ease of ordering and accessing CBD oil products from the comfort of your house.

There are also cheaper options online, and you can easily follow up on the legitimacy of the sellers. You can also access third-party lab testing results to know the purity and potency of the product you are about to buy.

Are you looking to buy CBD oil products in Missouri but you’re not sure whether it’s legal or not? Read to make an informed decision.

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CBD Oil in Honolulu, Hawaii

Honolulu, Hawaii

Curious about where to buy CBD oil in Honolulu? Look no further!

Our favorite CBD products can be purchased online for delivery to Honolulu, Hawaii:

What Is CBD?

As our awareness of the health benefits of cannabinoids grows, many people have become aware of CBD, but have questions about what it is and how it’s used. Firstly, CBD is non-psychoactive. Like THC, it is extracted from the cannabis plant and, like THC, has a variety of health benefits and recreational applications. But unlike THC, CBD is derived from the hemp plant (not the marijuana plant) and it is non-psychoactive. CBD does not produce a high, and is completely legal in all states. CBD oil can be vaped, ingested, or even applied topically, and produces a sensation of relaxation, making it extremely useful in the safe and natural relief of anxiety, insomnia, inflammation, pain, ADHD, epilepsy, and a number of other health conditions.
ity.

Hawaii does allow the tightly restricted use of marijuana for approved medical conditions, and Honolulu is home to two dispensaries. CBD, on the other hand, can be freely purchased at a number of CBD shops in Honolulu, including CBD stores in Ala Moana, Liliha – Kapalama, Kaka’ako and McCully – Moiliili. Buyers do not need a doctor’s approval or a medical marijuana card, and new users can be assisted by the CBD shop sales staff to select the right product for their needs.

CBD Shops in Honolulu

Buyers can find CBD stores in the Ala Moana, Liliha – Kapalama, Kaka’ako and McCully – Moiliili neighborhoods in Honolulu, but i’s also possible to purchase CBD from the comfort of home, as a large number of world-class and trusted online CBD stores ship CBD oil, tinctures, vape supplies, soft gels ands topically right to buyers doors. neighborhoods.

Best CBD Oil Shop in Liliha – Kapalama

Located near Nu’uano Stream, Mr. Hemp CBD (286 N School St Ste B Mr. Ink Plus Honolulu, HI 96817 Kalihi) can be found on the border of Liliha – Kapalama and Kalihi – Palama. Mr Hemp CBD claims to be the #1 supplier of CBD in Honolulu, and with their focused selection and expert staff, it’s likely quite true, and you’d be hard-pressed to find a more specialized store. Housed in the same storefront as Mr. Ink, a printer and toner ink supplier, Mr. Hemp CBD offers CBD from top brands like Pure Hemp Botanicals, Receptra, Green Roads, NuLeaf, iPuff, and Treatables. The staff is focused 100% on the sale of top quality CBD and has advanced expertise in recommending the right product to solve a variety of health and mood conditions and to produce specific effects. Delivery methods include CBD sprays, CBD oil tincture drops, CBD vape liquid, CBD balms, CBD mints, gummies and lollipops, CBD salves, CBD capsules, and even CBD dog treats.

Best CBD Oil Shop in Ala Moana

Located in Ala Moana, 710 Hawaii (1501 Makaloa St Honolulu, HI 96814) is convenient to residents of this neighborhood, and surrounding Waikiki and Kaka’ako. This tidy smoke shop stocks a range of artistic and standard glassware and accessories, along with a selection of natural CD products. Choice include organic edible CBD dried fruit rolls made with Hawaiian pineapple, coconut, strawberry and other fruit, CBD gummies, CBD vape liquid, CBD oil tinctures in various potencies, CBD dab wax, and CBD salves and lotions. There’s even CBD infused water and CBD soda in funky flavors like grape, melon, and Captain Crunch. The store carries established CBD brands like CBD Plus, Cannabinoid Creations, and local favorite, CBD Wellness Hawaii. The staff are friendly and knowledgable, and the store has earned a five-star Yelp rating, with customers giving props for selection and ease of shopping.

Best CBD Oil Shop in McCully – Moiliili

2Highguys (2570 S Beretania St Honolulu, HI 96826) is located close to the border of Mānoa, not far from the University of Hawaiʻi at Mānoa. As the name implies, this establishment is a classic head shop, complete with glassware, tobacco and smoke accessories, and novelty apparel. The store is known for its wide selection of fruity vape flavors mixed in-house, and for affordable prices, and shoppers report that 2Highguys has the best cheap CBD in Honolulu. CBD drip vape liquid is their most popular CBD product, and the store boasts an average of 4.5 stars on Yelp. This affordable CBD shop is open 7 days per week, and stays open until 9 pm most days.

Best CBD Oil Shop in Kaka’ako

Brahddahs Smoke Shop (232 Waimanu St Fl 2 Ste F Honolulu, HI 96814) is located in Kaka’ako on the border of Ala Moana. This friendly smoke and CBD shop specializes in wide selection and cheap prices, and customers award the store an impressive 5 star average on Yelp. Reviewers claim the store has the biggest CBD selection in the area, and there are certainly a lot of options in their inventory. Brahddahs Smoke Shop sells both sweet and savory CBD edibles, CBD syrups and honey, CBD vape cartridges, kids and vape liquids in various flavors, CBD capsules, CBD salves and balms, and CBD tinctures and sprays. The store stocks premium national brands like Green Roads, CBD Drip, Weetos, Hemp Bombs, Cloud N9ne, as well as local companies Hawaii Cannibus Care and CBD Wellness Hawaii.

Additional Resources:
CBD Oil in Hawaii

CBD Oil in Honolulu, Hawaii Curious about where to buy CBD oil in Honolulu? Look no further! Our favorite CBD products can be purchased online for delivery to Honolulu, Hawaii: What

Best CBD Oil in Hawaii

The Best Places to Buy CBD in Hawaii

As one of the most popular health and wellness products on the market, CBD is appearing in stores across the country, and Hawaii is no exception, with dozens of places to buy CBD products in Honolulu, Kahului, and the Island of Hawaii. If you’d rather buy CBD online, plenty of wholesale retailers are available: save on affordable CBD products, complimentary delivery service, and an excellent selection of CBD oils, juices, edibles, tinctures, and other CBD products in multiple grades.

Our favorite CBD product can be purchased online for delivery to Hawaii:

For your convenience, we’ve compiled the best places to buy CBD in Hawaii below, but first let’s review CBD’s legal status and the medical science behind the product.

Is CBD Legal in Hawaii?


Hawaii legalized medical marijuana back in 2000 with State Bill 862 HD1. It has been amended twice since that time, but the medical use of cannabis and marijuana-derived products remains legal for those who have a qualifying condition and a prescription from their doctor. Something interesting about the laws in Hawaii is that they are one of the only states that allows medical marijuana patients from other states to have access to the drug while they’re in Hawaii. Due to these laws, anyone who has a qualifying medical condition can use marijuana-derived CBD in the state of Hawaii.

For those of you who do not have a qualifying condition or just use CBD for recreational reasons, don’t fret. The use of hemp-derived CBD is legal for medicinal and recreational use in the state of Hawaii. They enacted a hemp research program all the way back in 2014. This program regulates the cultivation of industrial hemp but not the processing of the plant or products that are made from it. As long as you are purchasing hemp-derived CBD that meets the federal guidelines outlined in the Farm Bill that passed in 2018, you’re free to consume CBD.

What Is CBD?

There are over 85 cannabinoids in the cannabis plant, but CBD is different from other cannabinoids through the fact that is is non-psychotroipic. This makes CBD a safe, uncontroversial, and health-promoting alternative to similar products.

In particular, CBD affects the endocannabinoid system, which controls day-to-day functions including mood, sleep, hormone regulation, appetite, and pain. Evidence of progress in any of those categories would be a major breakthrough, but research suggests we’re only beginning to understand CBD’s greatest health advantages: dozens of chronic medical issues—cardiovascular disease, epilepsy, general anxiety disorders, schizophrenia, Alzheimer’s disease, and ALS, among others—might be reduced, mitigated, or prevented via regular CBD usage.

The more we learn about CBD’s potential health benefits, the more we’ll learn how to use it to reduce risks for everything from insomnia to depression to cancer.

CBD Oil Shops in Honolulu

Honolulu is home to a dozen shops selling premium CBD products. Mr. Hemp CBD (286 N School St, Honolulu, HI 96817) is a 5 star-rated shop selling CBD capsules, spray, salves, gummies, vape cartridges, and CBD oils. All the store’s products are tested by thirty-party labs to guarantee quality, and they are a certified retailer for NuLeaf Naturals, Hemp Health CBD and Green Roads CBD Products. 2Higuys (2570 S Beretania St, Honolulu, HI 96826) is another nearby CBD shop, with personalized customer service, an extensive inventory, and excellent hours seven days a week. Right next door is Choke Smoke (2671 S King St, Honolulu, HI 96826). In addition to excellent CBD options, Choke Smoke carries premium e-liquids, Kratom, vaporizers, dab pens, glass pipes, water pipes, rigs, hookahs, and more. If you’re downtown, check out Natural Mystic (203 S King St, Honolulu, HI 96813) for affordable CBD, e-juice, and vape accessories; and if you’re in the direction of Diamond Head, you can’t go wrong with VOLCANO eCigs (449 Kapahulu Ave, Honolulu, HI 96815), the island’s most popular CBD shop, which offers a variety of CBD products and online promotions.

Other highly-rated shops selling CBD: Smokey’s (159 Kaiulani Ave, Honolulu, HI 96815), Brahddahs Smoke Shop (1232 Waimanu St, Honolulu, HI 96814), Aloha Green Apothecary (1314 S King St, Honolulu, HI 96814), and the always-popular Fly Hi Hawaii (590 Farrington Hwy, Kapolei, HI 96707). Smokeless Hawaii Enterprises (719 Kamehameha Hwy
Pearl City, HI 96782) holds a perfect rating, with high marks for a deep inventory of CBD products and helpful staff. Finally, Down to Earth Organic & Natural (98-129 Kaonohi St, Aiea, HI 96701) is a health market that sells high-quality CBD in the vitamin/supplement section.

CBD Oil Shops in Kahului

There are two CBD shops in Kahului. First, Still Smokin’ – Kahului (346 North Market St, Wailuku, HI 96793), open seven days a week. Here you’ll find high-quality CBD oil, vaporizers, water pipes, and much more. For those interested in spa options, Maui Hemp Spa (930 Waine’e St, Lahaina, HI 96761) offers premium hemp-derived CBD massages using products developed in Hawaii.

CBD Oils Shops on The Island of Hawaii

Established in 2015, Hale Hookah (60 Waianuenue Ave, Hilo, HI 96720) holds a 5-star rating, with an extensive inventory of CBD products, vape accessories, Shisha, and Dokha tobacco. Customers highlight the knowledgeable staff, friendly customer service, and highly affordable CBD prices.

Additional CBD Resources:
CBD in Honolulu

Best CBD Oil in Hawaii The Best Places to Buy CBD in Hawaii As one of the most popular health and wellness products on the market, CBD is appearing in stores across the country, and Hawaii is

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What Is Full-Spectrum CBD?

Substance Made From All Extracts of the Cannabis Plant

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Cristina Mutchler is an award-winning journalist with more than a decade of experience in national media, specializing in health and wellness content. A multilingual Latina, Cristina’s work has appeared on CNN and its platforms, local news affiliates across the country, and in the promotion of medical journal articles and public health messaging.

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Meredith Bull, ND, is a licensed naturopathic doctor with a private practice in Los Angeles, California.

Full-spectrum CBD is a substance that contains all of the extracts naturally found in the cannabis plant, including very small amounts of THC, the psychoactive ingredient associated with the marijuana “high.”

It’s recently been popularized for its potential to help alleviate a variety of health conditions—like pain, anxiety, inflammation, and epilepsy—but more research is needed to fully back up all of the claims about its benefits.

Cannabis oil

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David Trood / DigitalVision / Getty Images

What It Is

Before exploring full-spectrum CBD, it’s helpful to understand what CBD is to begin with. CBD—short for cannabidiol—is what’s known as a cannabinoid, one of more than 100 chemical compounds found in the Cannabis sativa plant. Most CBD products are derived from the hemp species of that plant.

The two most well-known cannabinoids are CBD and THC:

  • Cannabidiol (CBD)is often derived from hemp and doesn’t usually cause a “high” on its own.
  • Tetrahydrocannabinol (THC)is the psychoactive compound that causes the euphoric “high” feeling associated with marijuana.

The Cannabis Plant

Both hemp and marijuana are species of the cannabis plant, and both contain CBD — but hemp plants have 0.3% THC or less, while marijuana plants have higher levels of THC.

Types

Ever since a 2018 federal law has made it legal to grow and sell hemp in the U.S., CBD has been popping up everywhere in different forms — from tablets to oils to creams to gummies.

Full-spectrum CBD is one of three main types of CBD available. It’s important to understand the differences between the most common types, as the ingredients do vary.

  • Full-spectrum CBD contains CBD and all other cannabinoids, including trace amounts of THC (0.3% or less).
  • Isolate CBD contains just CBD.
  • Broad-spectrum CBD contains CBD and multiple other cannabinoids, but no THC.

Some CBD connoisseurs consider full-spectrum CBD products to be more effective than the other forms, because they include all of the cannabis plant’s compounds plus up to 0.3% THC. That combination produces what researchers have dubbed the “entourage effect,” meaning that all of the elements in full-spectrum CBD may work better together than a single cannabinoid used alone.  

How It Works

The major cannabinoids found in full-spectrum CBD—CBD and THC—work on different areas of the brain. Researchers are still studying their full effects on the body, but what they have found is that cannabinoids in general help regulate the body’s endocannabinoid system.

That system is responsible for nervous and immune system function, along with mood, sleep cycle, and inflammation response regulation, and more. Basically, the endocannabinoid system helps correct many different imbalances within the body via activated receptors found throughout our central and peripheral nervous systems.

It’s also connected to the way we experience pain, prompting researchers to think that CBD helps the body’s systems achieve better balance.  

Benefits

So far, the U.S. Food and Drug Administration (FDA) has approved one cannabis-derived medication, a prescription drug product used to treat certain severe forms of epilepsy, a seizure-causing disorder.

While there’s currently no solid scientific evidence pointing to other specific health conditions that full-spectrum CBD may help treat, research suggests that in addition to acting as an anti-inflammatory, it shows promise for treating anxiety, panic, obsessive-compulsive disorder, and post-traumatic stress disorders in some people.

Risks

Here’s the million-dollar question: Does full-spectrum CBD get you “high,” since it technically contains trace amounts of THC? Generally speaking, experts say no, it should not produce a “high.” But the answer isn’t crystal clear and may vary by product and person.

The amounts of THC found in full-spectrum CBD are at low quantities of less than 0.3%, which is considered to be pretty insignificant. Many experts agree that such a small amount likely isn’t strong enough to have significant psychoactive effects, and likely wouldn’t register on a drug test, but you shouldn’t rule out those possibilities.

Some people may experience some of the milder psychoactive or sedative effects that are associated with THC, and there’s a chance it could show up on a drug test.

Side Effects

Because research on full-spectrum CBD is still fairly preliminary, experts don’t have all of the answers to many consumer questions about the pros and cons of using it for various health issues. That said, a 2018 World Health Organization (WHO) report indicates that CBD in general is typically well-tolerated, with reported adverse effects usually happening as a result of medication interactions.

Still, there’s a possibility for the following side effects to occur:

  • Mood changes
  • Appetite changes
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Nausea
  • Vomiting

Keep in mind that full-spectrum CBD is not regulated by the FDA, though the agency is currently working on how it may approach regulating the CBD industry in the future. For now, there is no guarantee that a full-spectrum CBD product is safe, or that it’ll be effective for you.

Standard and daily-use guidelines don’t exist, and ingredients and dosages may vary widely. It’s also worth noting that mislabeling appears to be a fairly common issue with CBD products, according to some studies.

It’s a good idea to read the label and ingredient list closely. You’ll want to look for added preservatives, flavorings, or other ingredients you don’t recognize, and double-check them online or confirm with a trusted medical source.

While you don’t need a prescription for full-spectrum CBD, consider checking with your doctor or healthcare professional to make sure it won’t counteract with any other medications you’re taking, and to ensure the condition you’re using it for makes sense based on what we know about the substance.

Legality

You may be confused about the legality of full-spectrum CBD. As referenced, hemp-derived CBD products containing less than 0.3% THC are legal federally, but may not be legal under some states’ legislation. You may want to check out local legislation before purchasing any CBD products (full-spectrum or not) and before traveling with CBD products to other states.

The decision to try full-spectrum CBD may depend on whether you are OK with consuming THC in any amount, particularly if marijuana or CBD is not legal in your state, or if you anticipate being drug tested.

Full-spectrum CBD is a substance made up of all chemicals found in the cannabis plant, popularized for its potential to ease pain and other ailments.

Full-spectrum CBD oil

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Contents

  1. More about full-spectrum CBD oil
  2. Are all CBD oils the same?
  3. Can you buy full-spectrum CBD oil online?
  4. Full-spectrum CBD oil vs. CBD isolate
  5. Does CBD oil get you high?
  6. Do you need a prescription for CBD oil?
  7. What does CBD feel like?
  8. Does CBD make you paranoid?

Also known as whole-plant cannabidiol (CBD) oil, full-spectrum CBD oil is a cannabis oil with high concentrations of CBD, as well as all other cannabinoids, terpenes, and trace amounts of THC found in the cannabis plant.

“I’ve heard full-spectrum CBD oil is preferable to isolated CBD.”

“What’s the difference between broad-spectrum and full-spectrum CBD oil?”

More about full-spectrum CBD oil

When a CBD oil product claims to be the result of a full-spectrum extraction process, that means the plant’s original terpenes and other types of cannabinoids, including cannabinol (CBN), cannabigerol (CBG), and trace amounts of THC, have not been filtered out during the extraction process.

Before you can choose a CBD oil that may work for you, from full-spectrum to other product types, it’s important to know the difference between hemp-derived CBD oil and marijuana-derived CBD oil.

Following the passage of the 2018 Farm Bill, the U.S. government effectively legalized industrial hemp-derived CBD products that contain no more than 0.3% THC, placing hemp-based CBD oil under the jurisdiction of the Food and Drug Administration (FDA). Because industrial hemp-derived products only have trace amounts of THC, this type of CBD oil will not produce any intoxicating effects in consumers. Many hemp-derived CBD products can be purchased online .

Marijuana-derived CBD oil typically contains both THC and CBD, the measurements of which vary depending on the CBD-to-THC ratio. Marijuana plants typically have copious amounts of resin, often containing significantly higher levels of both THC and CBD than industrial hemp plants. CBD oil that contains more than 0.3% THC can only be purchased in legal adult-use states and by patients in select legal medical marijuana states, making hemp-derived CBD oil the only legally viable option for some.

Are all CBD oils the same?

No, and not only because of the distinction mentioned above. There are many different products. The easiest way to understand how CBD oils are different is to put them into one of three categories: full spectrum, broad spectrum, and isolate. Full-spectrum CBD oil contains the full spectrum of compounds from a high-CBD cannabis or hemp plant. Broad-spectrum CBD oil contains a nearly full spectrum of compounds, but with the trace amounts of THC removed. CBD isolate, also known as raw CBD oil, strips away all other cannabinoids, leaving pure CBD. Full and broad-spectrum CBD oils may also contain varying doses of actual CBD.

There are three categories of CBD oil: full spectrum, broad spectrum, and isolate. Photo by: Gina Coleman/Weedmaps

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When shopping for CBD oil, keep these oil types in mind as a basic CBD buying guide. When purchasing full-spectrum CBD oil, it’s also helpful to know signs of safe, authentic CBD oil labeling , and avoid any product that makes big claims about curing diseases or conditions.

Can you buy full-spectrum CBD oil online?

As long as it’s hemp-derived, you may be able to find full-spectrum CBD oil in online stores . Most online CBD oil purchases can be made at a brand’s own website through an internal checkout.

Full-spectrum CBD oil vs. CBD isolate

Is it more preferable to have a full spectrum of compounds in CBD oil or a pure CBD isolate? There is no definitive answer, given the myriad reasons a person may be choosing CBD oil. What works medicinally for one individual may not work for another. With that in mind, a full spectrum of cannabis compounds can be more effective than a single compound, including CBD, on its own. Cannabinoids and terpenes from the cannabis plant work together synergistically, potentially becoming more therapeutic as an ensemble, in what’s referred to as the ensemble or entourage effect.

Does CBD oil get you high?

No. CBD will not create the same high that THC does. While the effects are completely different than THC, it’s technically true that CBD is a psychoactive substance , which is defined as a chemical substance that interacts with the central nervous system and alters brain function, resulting in temporary changes in perception, mood, consciousness, and behavior. However, unlike THC , CBD is non-intoxicating and will not make you feel stoned or buzzed.

Do you need a prescription for CBD oil?

No. You don’t need a doctor’s recommendation or prescription to use hemp-derived CBD oil. In fact, following the legalization of industrial hemp-based products, CBD oil can be purchased online or, in many states, even in local pharmacies. However, access to marijuana-derived CBD oil containing higher levels of THC is limited to states with medical or adult-use legalization in place.

What does CBD feel like?

CBD is said by many to have a relaxing and soothing effect, but you won’t necessarily feel this non-intoxicating cannabinoid the same way you would THC. To explain how CBD truly feels, we need to understand how both THC and CBD interact with the endocannabinoid system (ECS). The ECS is made up of endocannabinoids, receptors that cannabinoids bond to, and enzymes that break them down.

While THC activates the CB1 receptors, CBD induces the opposite outcome, instead inhibiting activity in the CB1 receptors. In fact, existing research suggests that this inhibition is enhanced when combined with THC, leading to a more mellow high and reducing the adverse effects of THC, such as anxiety and paranoia.

The interaction between CBD and the body may create a feeling of relaxation and improved mood. Photo by: Gina Coleman/Weedmaps

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The interaction between CBD and the body may create a feeling of relaxation and improved mood, and offers therapeutic value in the treatment of pain, inflammation, anxiety, and other ailments.

Does CBD make you paranoid?

No. Using even high doses of CBD will not cause you to have a paranoia or an uneasy high feeling. Although both paranoia and anxiety have been reported as adverse side effects of THC, CBD consumers are not at risk of encountering the same mental distress. According to the Mayo Clinic, the Minnesota-based nonprofit academic medical center, side effects of CBD use are typically limited to dry mouth, diarrhea, reduced appetite, drowsiness, and fatigue.

Full-spectrum CBD oil Copy article link to clipboard. Link copied to clipboard. Contents More about full-spectrum CBD oil Are all CBD oils the same? Can you buy

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Office of Drug & Alcohol Policy & Compliance

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Washington , DC 20590
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Email: [email protected]
Phone: 202-366-3784
Alt Phone: 800-225-3784
Fax: 202-366-3897

DOT “CBD” Notice

DOT OFFICE OF DRUG AND ALCOHOL POLICY AND COMPLIANCE NOTICE

The Agricultural Improvement Act of 2018, Pub. L. 115-334, (Farm Bill) removed hemp from the definition of marijuana under the Controlled Substances Act. Under the Farm Bill, hemp-derived products containing a concentration of up to 0.3% tetrahydrocannabinol (THC) are not controlled substances. THC is the primary psychoactive component of marijuana. Any product, including “Cannabidiol” (CBD) products, with a concentration of more than 0.3% THC remains classified as marijuana, a Schedule I drug under the Controlled Substances Act.

We have had inquiries about whether the Department of Transportation-regulated safety-sensitive employees can use CBD products. Safety-sensitive employees who are subject to drug testing specified under 49 CFR part 40 (Part 40) include: pilots, school bus drivers, truck drivers, train engineers, transit vehicle operators, aircraft maintenance personnel, fire-armed transit security personnel, ship captains, and pipeline emergency response personnel, among others.

It is important for all employers and safety-sensitive employees to know:

  1. The Department of Transportation requires testing for marijuana and not CBD.
  2. The labeling of many CBD products may be misleading because the products could contain higher levels of THC than what the product label states. The Food and Drug Administration (FDA) does not currently certify the levels of THC in CBD products, so there is no Federal oversight to ensure that the labels are accurate. The FDA has cautioned the public that: “Consumers should beware purchasing and using any [CBD] products.” The FDA has stated: “It is currently illegal to market CBD by adding it to a food or labeling it as a dietary supplement.”* Also, the FDA has issued several warning letters to companies because their products contained more CBD than indicated on the product label. **[i]
  3. The Department of Transportation’s Drug and Alcohol Testing Regulation, Part 40, does not authorize the use of Schedule I drugs, including marijuana, for any reason. Furthermore, CBD use is not a legitimate medical explanation for a laboratory-confirmed marijuana positive result. Therefore, Medical Review Officers will verify a drug test confirmed at the appropriate cutoffs as positive, even if an employee claims they only used a CBD product.

It remains unacceptable for any safety-sensitive employee subject to the Department of Transportation’s drug testing regulations to use marijuana. Since the use of CBD products could lead to a positive drug test result, Department of Transportation-regulated safety-sensitive employees should exercise caution when considering whether to use CBD products.

The contents of this document do not have the force and effect of law and are not meant to bind the public in any way. This document is intended only to provide clarity to the public regarding existing requirements under the law or agency policies. This policy and compliance notice is not legally binding in its own right and will not be relied upon by the Department as a separate basis for affirmative enforcement action or other administrative penalty. Conformity with this policy and compliance notice is voluntary only and nonconformity will not affect rights and obligations under existing statutes and regulations. Safety-sensitive employees must continue to comply with the underlying regulatory requirements for drug testing, specified at 49 CFR part 40.

DOT OFFICE OF DRUG AND ALCOHOL POLICY AND COMPLIANCE NOTICE

Can Truck Drivers Use CBD Oil? A 2020 Guide

Written By: Armela Escalona

With all the madness surrounding COVID-19, truck drivers have stepped up in a big way for us. These heroic men and women have been driving around-the-clock to help us hold on to some normalcy during these uncertain times.

So in light of their perseverance and dedication, we wanted to take a moment to share our gratitude and answer questions that we’ve been getting from these patriotic road warriors, as well as expand on some additional topics.

To start, the use of cannabis for medical and recreational purposes is now legal in 11 U.S states . Cannabis-derived products, such as cannabidiol (CBD) oils, are now federally legal.

Surely you’ve seen several advertisements that market the product as add-ins for your favorite drinks (coffee or smoothie) or a great addition to your natural skincare routine.

And despite all its popularity, many people are still unsure about CBD and are concerned about its effects, including our 18-Wheelin’ friends. So, Can truck drivers use CBD oil? Is it safe to drive after using CBD oil? Is CBD legal?

Can Truck Drivers Use CBD Oil?

CBD oil is federally legal in the United States, so yes truck drivers, just like anyone else, can use CBD products. Keep in mind that the laws regarding CBD’s status have varying degrees of restrictions. Some states allow the full use of the product while others restrict it altogether. Not confusing at all, right?

If you are driving through multiple states, it’s a good idea to take a look at the restrictions for each one. Here’s a map to help you safely navigate cannabis law.

can truck driver use cbd oil? a 2020 US CBD legality map

There are a few states highlighted in purple which either restrict cannabis products or do not regulate them at all. The three states where it is not legal in any form are South Dakota, Idaho, and Iowa. Avoid these states if possible if you’re using CBD or low THC products.

In teal states like California and Colorado, all cannabis products are both medicinally and recreationally legal, so no issues there.

The states highlighted in yellow, like Florida and Arizona, have legalized medicinal cannabis and allow for over-the-counter CBD and low THC products.

And the states highlighted in orange, like Georgia and Tennessee, only allow CBD and low THC products.

So if you’re driving cross-country with CBD, the only three states you have to worry about are South Dakota, Idaho, and Iowa.

Can I use CBD while driving?

Generally speaking, CBD oil is safe to use throughout the day. Even if you purchase a full-spectrum CBD product that contains trace amounts of THC, it’s not going to have an intoxicating effect on you.

Some customers have reported a drowsy or sleepy side-effect from taking CBD, so if you have a similar experience, we do not recommend you operate a motorized vehicle. It’s always a good idea to speak with a physician to find a dose that works best for you before integrating it into your day-to-day.

What if I get pulled over with CBD?

You got pulled over and you have CBD? Don’t panic, remember, CBD is federally legal. Again, it’s a good idea to keep local and state regulations in mind when purchasing and consuming any product, but if you did your homework beforehand and it’s permissible where you’re driving, then you’re in the clear.

Regardless, any quality CBD brand will make their lab tests accessible on their website, and depending on the state, the product must be properly labeled and include a QR code linked to the lab tests for that specific batch. This is important because those 3rd party lab tests confirm that the product contains the legal amount of 0.3% or less in THC.

So if you’re ever in doubt, simply scan the QR code with your phone and keep the lab tests handy while.

cbd oil lab test

What’s in CBD Oil? — Why is there an ongoing debate about its legality?

Cannabidiol or CBD is a secondary compound found in the cannabis sativa plant. The primary compound—which is also the more famous one— is tetrahydrocannabinol or “THC”. This is the active ingredient that induces the psychoactive or euphoric effect of cannabis.

THC and CBD are just two of the more than 80 organic cannabinoids present in the plant. According to researchers, cannabinoids are the chemicals that protect the plant from UV rays. Cannabinoid levels also change with sun exposure . This is why the flowers from the female plant often have more cannabinoids than the rest of the plant.

THC and CBD only have slight differences when you look at their chemical structure. Despite this, they’re very different when it comes to their effects. While THC’s psychoactive effect helps with ailments like nausea, CBD is shown to aid in relieving inflammation, joint pain and aches, as well as mood and overall mental health. Experts are also studying CBD and its effects on children and teens with drug-resistant epilepsy.

What Are The Benefits of CBD Oil?

With excellent anti-inflammatory and antioxidant properties, CBD has been shown to offer some health benefits, both physical and mental. The most promising include studies that point to early clinical trial data showing CBD’s efficacy with regard to epilepsy and varying forms of seizures .

Marijuana users often claim they use the drug for its calming effects. This effect is also seen in CBD users and may include relief from neuropathic pain and anxiety, as well as cognitive symptoms associated with Alzheimer’s and Dementia .

CBD oil is also known for its benefits on the skin . Findings show that the fatty acids present in the oil can protect the skin from breakouts and inflammation whilst keeping the skin nourished and moisturized. It can also aid with various skin conditions such as dermatitis, lichen planus, acne rosacea, and eczema.

There are still no clear findings on the mental health benefits of CBD and THC. Early trials show some encouraging data but it’s still too early to tell if CBD and THC are effective in treating psychiatric disorders.

Some studies showed promise in CBD’s ability to aid those who suffer from social anxiety, insomnia, and post-traumatic stress disorder. But as always, we recommend you speak with your primary care physician before taking any products.

Is CBD Oil Safe?

CBD oil is generally safe but there are side effects and risks that you should consider. Side effects of cannabidiol can include irritability, fatigue, and nausea. Other rare side effects include gastrointestinal problems, appetite loss, and altered liver enzymes.

The product is advised against women who are trying to conceive, or are pregnant or currently breastfeeding because ingredients in the cannabidiol products may be harmful to infants or fetuses.

CBD is also not recommended for people who are immune-compromised as well as people with liver disease and people with Parkinson’s disease. Studies found that cannabidiol actually worsens tremors and muscle movements in people with this disease.

What You Need To Know

As of 2020, the general rule of thumb for CBD consumers is this: CBD products are illegal in South Dakota, Iowa, and Idaho, but legal in every other state.

If you’re a truck driver and currently working, it is safe to take CBD products but make sure to avoid the states listed above. Also, don’t drive and take CBD products if they make you drowsy.

Remember, if you get pulled over by a police officer, kindly show him the lab tests for the product and the receipt for the purchase. Again, it’s perfectly legal in most states to have CBD products with you.

And lastly, speak to a physician when deciding what product and dose is best for you and your specific needs. Stay safe out there!

As of 2020, the general rule of thumb for CBD consumers is this: CBD products are illegal in South Dakota, Iowa, and Idaho, but legal in every other state. If you're currently driving through multiple states, make sure to keep your purchase receipt and 3rd party lab tests handy. Continue reading for more details.

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cbd day

What Dosage of CBD Should You Take?

Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital.

A bottle of CBD oil and a medicine dropper

Iryna Veklich / Getty Images

CBD is available in a number of different formulations including creams, tablets, oils, and gummies. These can vary in terms of their ingredients as well as dosages, and there is not a great deal of research available on what dose might be beneficial or safe to treat certain conditions.

Cannabidiol (CBD) is the second most abundant cannabinoid found in marijuana. Unlike tetrahydrocannabinol (THC), CBD does not have psychoactive effects. Interest in the use of CBD for health purposes has grown tremendously in the last few years.

CBD is believed to have a range of positive physical and mental health effects. Because of this, it has become increasingly popular as a way to alleviate everything from anxiety to sleep disorders.

In order to determine if CBD is right for you, it is important to consider its potential benefits, side effects, and available research on safe dosages.

Possible Benefits

CBD is just one of hundreds of different compounds found in the cannabis plant. While cannabis has been used in holistic medicine for many years, only recently have researchers begun to explore some of the medicinal purposes for CBD and other cannabinoids.

While further research is still needed, there is some evidence that CBD may have some beneficial mental health effects. These include:

  • Alleviating depression: Some research also indicates that CBD may be useful as a treatment for depression. Studies suggest that the cannabinoid might have an influence on how the brain responds to serotonin, a neurotransmitter that plays a key role in mood.   People with depression sometimes have a low level of serotonin, so CBD may help the brain use available serotonin more effectively.
  • Improving sleep: While the reasons are not entirely understood and require further research, CBD also appears to have potential as a treatment for sleep problems. For example, one study found that people who took CBD also reported improvements in the quality of their sleep.  
  • Reducing anxiety: Anxiety is one of the most common types of mental health conditions, affecting almost 20% of American adults each year. Research suggests that CBD may help alleviate acute symptoms of a number of anxiety-related conditions including generalized anxiety disorder, obsessive-compulsive disorder, and social anxiety disorder.  

In addition to the mental health benefits, CBD may also have therapeutic benefits for a range of other conditions. The World Health Organization suggests that CBD may have beneficial effects in the treatment of:  

  • Alzheimer’s disease
  • Arthritis
  • Cardiovascular disease
  • Diabetes
  • Infection
  • Inflammation
  • Multiple sclerosis
  • Nausea
  • Pain
  • Psychosis

It is important to remember that these benefits have not yet been conclusively proven. More research is needed to determine the role that CBD might play in the treatment of different disorders and health conditions.

Research

There have been a number of studies that suggest that CBD may have a number of different physical and mental health uses. However, more research is still needed to better understand the substance’s potential applications and possible long-term side effects.

A 2019 comprehensive review published in The Lancet Psychiatry looked at previously published studies.   The review ultimately concluded that there was little evidence to support the use of CBD for mental health purposes and suggested that more research is needed in order to substantiate its use to treat symptoms of conditions such as anxiety, depression, and insomnia.

It is important to remember that this doesn’t mean that CBD isn’t effective. Many of the studies that were included in the review were small, had few participants, and were not randomized controlled trials.

This suggests that more research involving more participants and well-designed studies is needed in order to better understand if, how, and why CBD works.

While its effectiveness is still up for debate, one 2017 review found that it was a relatively safe option.   While it is important to remember that there is still a great deal we don’t yet know about CBD and its effects, it is something that you might opt to try to see if you experience any benefits.

How Much Should You Take?

The dosages used in research studies vary and there is no consensus on how much should be used for specific conditions. If you do decide to try CBD, it is also important to note that there is no universally agreed upon dose. Research also suggests that people may respond differently to various dosages, so the amount that is right for your needs might vary.

CBD Dosages

Some dosages that have been used in research studies for different conditions include:

  • Anxiety: 300 to 600 mg  
  • Bowel disease: 10 mg per day  
  • Cancer-related pain: 50 to 600 mg per day  
  • Parkinson’s disease: 75 to 300 mg per day  
  • Poor sleep: 25 mg per day  
  • Psychosis: 600 mg per day  

One 2020 review of studies found that participants showed improvements in anxiety levels after single doses of CBD ranging from 300 to 600 mg.   Such results indicate that the CBD may hold promise as a treatment to alleviate symptoms of acute anxiety.

It is important to remember that you should always talk to your doctor before using CBD if you have symptoms of a serious mental or physical health condition. CBD could potentially worsen symptoms or interact with other medications you are taking.

Looking at the dosage information for the CBD product that has been FDA approved can also be helpful. For Epidiolex, an FDA-approved cannabis-derived medication used to treat seizures in people with certain types of epilepsy, the starting dosage is 5 milligrams per kilogram of body weight. This dose can later be increased to 5 mg per kilogram of body weight twice a day.

Other CBD products are not FDA regulated and do not have officially recommended dosages. This can make it difficult to determine how much you might need, but there are some things you can consider that might help.

  • Assess your sensitivity to CBD: Your individual ability to tolerate CBD can also play a role in determining how much you need. If you are very sensitive to the effects of CBD, you should take a small dose. Some people may find that they are not as affected by the substance, so they may need to take a larger dose to notice any beneficial effects.
  • Consider individual factors: When you are trying to decide how much CBD to take, there are a number of factors you should consider. These include the formulation and concentration of the capsule, oil drops, or gummies you are taking, the symptoms you are treating, and your age, sex, weight, and overall health. Generally, people with heavier bodies need to take a little more to achieve the same effects. Men may need a larger dose, while older people may need less.
  • Consider the symptoms you’re treating: The symptoms you are trying to alleviate can also play a role in the CBD dosage you need to take to see results. In one study, participants who took 25mg of CBD each day had improved sleep quality, although the results were not consistent.   However, you might find that you need a lower or higher dose if you are treating another type of condition.
  • Try a dosage calculator: Researchers note that while the variety of dosing strategies and formulations make it difficult to determine efficacy, there are a number of online “dose-calculators” available online (such as mydosage.com) that are designed to help people choose the correct dose.   The accuracy of such calculators is difficult to assess, but it may be a good place to start.

Before you try CBD, discuss your plan with your doctor. They may be able to recommend a dose and help you better understand any potential risks, complications, side effects, or interactions you might experience.

Start With a Low Dose

Unless your doctor recommends a specific dose, start by taking 10 to 20 mg a day. Take this for a week to ensure that it is well-tolerated and that you don’t experience any unwanted effects or an allergic reaction.

If this dose does not have the desired effect, try increasing in increments of 5mg each week until the desired amount is reached.

In studies, amounts vary from as low as 20 milligrams per day to up to 1,500 milligrams (mg) per day. The World Health Organization reports that dosages in clinical research studies typically range between 100 and 800 milligrams per day.  

Is It Possible to Take Too Much?

So what is the maximum amount of CBD you should take? Researchers have found that 600 mg per day appears to be safe, but one study suggested that doses of up to 1,500 mg a day are safe and tolerated well.  

However, it’s important to remember that research is still in its infancy and experts do not yet fully understand the potential long-term impacts of CBD usage. For that reason, you should always discuss your CBD use with your doctor.

Starting at a lower dose and working your way up to the amount you need may be the best ways to avoid taking too much.

How to Take CBD

The amount of CBD found in a product may depend on different factors, including the formulation and method of administration. CBD products are available in a number of different forms including oils, capsules, tablets, nasal sprays, and gummies.

One of the most popular ways to take CBD is as an oil. Such products are made by combining CBD with some type of carrier oil, such as coconut oil. Some more recently developed products include dietary supplements, foods, beverages, lotions, salves, and cosmetics.

The type of CBD product you choose may depend on what you are trying to treat. If you are looking for general mood improvements, a dietary supplement might be a good option.

If you are targeting specific symptoms of a condition, taking an oil, capsule, or gummy might be a better way to obtain a higher, more concentrated dose.

Topical applications may produce localized effects, but they are unlike to have any mental health benefits.

What Kind Should You Take?

It’s also important to remember that many products don’t contain just CBD on its own. There are three types of CBD available:

  • Isolate contains CBD and only CBD.
  • Broad-spectrum contains CBD and other cannabinoids, but not THC.
  • Full-spectrum contains CBD, THC, and other cannabinoids.

It may be helpful to take a broad-spectrum product since research suggests that CBD’s effects may be most beneficial when taken in conjunction with other cannabinoids, a phenomenon known as the entourage effect. CBD may also help mitigate some of the effects of THC.

Side Effects

While CBD is generally well-tolerated, this does not mean that you won’t experience any side effects.

Some of the most common side effects that people experience when taking CBD include:

  • Appetite changes
  • Diarrhea
  • Nausea
  • Dizziness
  • Stomach upset
  • Weight changes

Some recent research has generated concerns over the safety and potential long term effects of CBD. One study involved giving mice an equivalent of the maximum dose of the CBD medication Epidiolex, which is used to treat certain forms of epilepsy. The results indicated an increased risk for liver damage as well as concerns over its interaction with other medications.  

Safety

It is also important to remember that CBD products are not regulated by the U.S. Food and Drug Administration (FDA). Some manufacturers make unproven claims about the uses and efficacy of their products. There is also concern about the quality and safety of the products themselves.

One report by the Centers for Disease Control and Prevention (CDC) indicated that a number of people experienced negative unwanted side effects due to CBD products that contained synthetic CBD, although the products were not labeled as containing such ingredients.  

Mislabeling appears to be a fairly common problem with CBD products. In one study, 70% of the CBD products that were sold online contained significantly more of the psychoactive ingredient THC than the label indicated.  

Federal law prohibits the sale of products that contain more than 0.3% THC. States laws also vary, so you should always check with your state before buying CBD products online.

A Word From Verywell

If you do decide to take CBD to alleviate an acute or chronic condition, remember that the amount that you take will depend on a variety of factors. Finding the right dosage often takes some experimentation and adjustments. Starting with a low dose and then gradually increasing the amount you take until you achieve the desired effects is the best approach.

CBD holds promise as a treatment for a range of conditions, but how much should you take? Learn more about CBD dosages for different purposes.

Cbd day

On August 8th, National CBD Day recognizes the natural hemp product everyone’s clamoring for! Learn about CBD and updated laws impacting its use.

Over the years, hemp-derived CBD (cannabidiol) has made quite a name for itself in the wellness world. Since a growing number of products – from tinctures to topicals – hit the marketplace, CBD continues to be shoppers’ favorite option for holistic alternatives. As an added bonus, CBD does not possess the psychoactive properties of THC.

Another advantage of CBD is that it is naturally sourced and extremely versatile. Try swallowing it, vaping it, rubbing it on your skin, or bathing in it. You can even give it to your pets!

CBD Through the Ages

The hemp plant has withstood the test of time and politics; herbalists have long used hemp to promote wellness, while farmers have grown it as a source of fiber to make cloth and rope. But in the 20th century, governments clamped down on all things cannabis and everything related to it.

Nowadays, political leaders recognize what scientists long knew: properly sourced CBD won’t get you high. Since 2018, the federal government has defined hemp, which has little or no THC in it (less than .03% to be exact), as a legal plant that is distinct from marijuana. Therefore, hemp-based products like CBD oil don’t fall under national anti-drug laws.

HOW TO OBSERVE #NationalCBDDay

Seek the powerful properties of CBD and experience the wealth of natural relief and recovery. Join others seeking natural support on #NationalCBDDay, and get proactive about your wellness regimen.

Don’t forget to use the hashtag on social media to help spread the message on #NationalCBDDay.

NATIONAL CBD DAY HISTORY

cbdMD founded National CBD Day to bring awareness to what CBD (cannabidiol) brings to millions of people annually.

The Registrar at National Day Calendar proclaimed National CBD Day to be observed annually beginning on August 8, 2018.

There are over 1,500 national days. Don’t miss a single one. Celebrate Every Day® with National Day Calendar ®!

On August 8, National CBD Day recognizes the natural hemp product everyone's clamoring for! Learn about CBD and updated laws impacting its use.

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epidiolex cbd oil

U.S. Food and Drug Administration

FDA News Release

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The U.S. Food and Drug Administration today approved Epidiolex (cannabidiol) [CBD] oral solution for the treatment of seizures associated with two rare and severe forms of epilepsy, Lennox-Gastaut syndrome and Dravet syndrome, in patients two years of age and older. This is the first FDA-approved drug that contains a purified drug substance derived from marijuana. It is also the first FDA approval of a drug for the treatment of patients with Dravet syndrome.

CBD is a chemical component of the Cannabis sativa plant, more commonly known as marijuana. However, CBD does not cause intoxication or euphoria (the “high”) that comes from tetrahydrocannabinol (THC).

It is THC (and not CBD) that is the primary psychoactive component of marijuana.

“This approval serves as a reminder that advancing sound development programs that properly evaluate active ingredients contained in marijuana can lead to important medical therapies. And, the FDA is committed to this kind of careful scientific research and drug development,” said FDA Commissioner Scott Gottlieb, M.D. “Controlled clinical trials testing the safety and efficacy of a drug, along with careful review through the FDA’s drug approval process, is the most appropriate way to bring marijuana-derived treatments to patients. Because of the adequate and well-controlled clinical studies that supported this approval, prescribers can have confidence in the drug’s uniform strength and consistent delivery that support appropriate dosing needed for treating patients with these complex and serious epilepsy syndromes. We’ll continue to support rigorous scientific research on the potential medical uses of marijuana-derived products and work with product developers who are interested in bringing patients safe and effective, high quality products. But, at the same time, we are prepared to take action when we see the illegal marketing of CBD-containing products with serious, unproven medical claims. Marketing unapproved products, with uncertain dosages and formulations can keep patients from accessing appropriate, recognized therapies to treat serious and even fatal diseases.”

Dravet syndrome is a rare genetic condition that appears during the first year of life with frequent fever-related seizures (febrile seizures). Later, other types of seizures typically arise, including myoclonic seizures (involuntary muscle spasms). Additionally, status epilepticus, a potentially life-threatening state of continuous seizure activity requiring emergency medical care, may occur. Children with Dravet syndrome typically experience poor development of language and motor skills, hyperactivity and difficulty relating to others.

Lennox-Gastaut syndrome begins in childhood. It is characterized by multiple types of seizures. People with Lennox-Gastaut syndrome begin having frequent seizures in early childhood, usually between ages 3 and 5. More than three-quarters of affected individuals have tonic seizures, which cause the muscles to contract uncontrollably. Almost all children with Lennox-Gastaut syndrome develop learning problems and intellectual disability. Many also have delayed development of motor skills such as sitting and crawling. Most people with Lennox-Gastaut syndrome require help with usual activities of daily living.

“The difficult-to-control seizures that patients with Dravet syndrome and Lennox-Gastaut syndrome experience have a profound impact on these patients’ quality of life,” said Billy Dunn, M.D., director of the Division of Neurology Products in the FDA’s Center for Drug Evaluation and Research. “In addition to another important treatment option for Lennox-Gastaut patients, this first-ever approval of a drug specifically for Dravet patients will provide a significant and needed improvement in the therapeutic approach to caring for people with this condition.”

Epidiolex’s effectiveness was studied in three randomized, double-blind, placebo-controlled clinical trials involving 516 patients with either Lennox-Gastaut syndrome or Dravet syndrome. Epidiolex, taken along with other medications, was shown to be effective in reducing the frequency of seizures when compared with placebo.

The most common side effects that occurred in Epidiolex-treated patients in the clinical trials were: sleepiness, sedation and lethargy; elevated liver enzymes; decreased appetite; diarrhea; rash; fatigue, malaise and weakness; insomnia, sleep disorder and poor quality sleep; and infections.

Epidiolex must be dispensed with a patient Medication Guide that describes important information about the drug’s uses and risks. As is true for all drugs that treat epilepsy, the most serious risks include thoughts about suicide, attempts to commit suicide, feelings of agitation, new or worsening depression, aggression and panic attacks. Epidiolex also caused liver injury, generally mild, but raising the possibility of rare, but more severe injury. More severe liver injury can cause nausea, vomiting, abdominal pain, fatigue, anorexia, jaundice and/or dark urine.

Under the Controlled Substances Act (CSA), CBD is currently a Schedule I substance because it is a chemical component of the cannabis plant. In support of this application, the company conducted nonclinical and clinical studies to assess the abuse potential of CBD.

The FDA prepares and transmits, through the U.S. Department of Health and Human Services, a medical and scientific analysis of substances subject to scheduling, like CBD, and provides recommendations to the Drug Enforcement Administration (DEA) regarding controls under the CSA. DEA is required to make a scheduling determination.

The FDA granted Priority Review designation for this application. Fast-Track designation was granted for Dravet syndrome. Orphan Drug designation was granted for both the Dravet syndrome and Lennox-Gastaut syndrome indications.

The FDA granted approval of Epidiolex to GW Research Ltd.

FDA approved Epidiolex (cannabidiol) oral solution, the first drug comprised of an active ingredient derived from marijuana, to treat two rare and severe forms of epilepsy.

Cannabidiol oral solution

Epidiolex ® (EH-peh_DYE-oh-lex) oral solution CV is the brand name for the cannabidiol oral solution, also referred to as CBD, from Greenwich Biosciences. The name or look may be different in other countries, but the dose (measured in milligrams, abbreviation “mg”) usually will be the same. Epidiolex is a quality grade of cannabidiol oil that is different from CBD or cannabidiol that is not U.S. Food and Drug Administration (FDA) approved.

Epidiolex is Approved for Use:

In people age 2 years and older for seizures associated with Lennox-Gastaut Syndrome and Dravet Syndrome.

Forms

Cannabidiol oral solution is availabe as 100 mg in each milliliter (abbreviated as “mL”).

  • Each bottle contains 100 mL of a clear colorless to yellow solution with a strawberry flavor.
  • Two 5 mL syringes will come with each bottle of medicine. These can be reused.
  • A 1 mL syringe is available from the pharmacist when smaller doses are needed.

Dosing

Blood tests for liver function, called serum transaminases (ALT and AST) and total bilirubin levels should be done in each person before starting Epidiolex.

The dose in children is based on weight, written as milligrams per kilograms or “mg per kg”. It is important to follow the instructions given by the prescribing health care provider.

  • The recommended starting dose is 2.5 mg per kg taken twice a day. (Total daily dose would be 5 mg per kg).
  • Your provider may recommend increasing the dose after 1 week to 5 mg per kg twice a day. (Total daily dose would be 10 mg per kg).
  • Epidiolex can be increased higher if needed to 10 mg per kg twice a day. (Total daily dose would be 20 mg per kg).
  • The dose may be different or changed for people with liver problems.

How To Take:

Take Epidiolex exactly as your health care provider prescribes it. Do not change your dose without talking to your provider first. Stopping a seizure medicine suddenly can cause seizures that will not stop (status epilepticus).

  • Take the medicine twice a day by mouth.
  • Check the amount and concentration of the oral solution from the pharmacy.
  • A special measuring device (called a syringe) will come with each prescription bottle. Use this syringe to measure the exact dose of medicine. Do not use a regular teaspoon to measure the medicine.
  • Use a dry syringe each time you measure a dose of Epidiolex. Water inside the syringe could make the oil-based medicine look cloudy.
  • Take the medicine about the same time each day with or without food. Certain foods can increase the amount of Epidiolex that is absorbed in your body, so take it the same way each day.
  • Take only the amount that your provider tells you to take.
  • If you take an extra dose, call your provider for advice.
  • If you take a larger amount of the liquid, call the poison control center (800-222-1222) or call your hospital emergency department for instructions.
  • When Epidiolex is stopped, the dose should be lowered slowly. Your provider will give you specific instructions on how to do this.

How To Store:

  • Store Epidiolex in its original bottle in an upright position at 68°F to 77°F.
  • Do not refrigerate or freeze the medicine.
  • Keep the child proof cap closed tightly.
  • Use the medicine within 12 weeks of first opening the bottle. Throw away any unused medicine after 12 weeks.
  • Keep Epidiolex out of reach of children.

Taking the right amount of seizure medicine, on time every day, is the most important way to control seizures.

  • If you miss a dose, take it as soon as you remember it.
  • If it is almost time for the next dose, skip the missed dose and take the next dose at the regular time.
  • Avoid taking 2 doses at the same time or taking extra doses.
  • If you are not sure about what to do, call your provider’s office for advice and follow their directions.
  • To avoid missed doses, set an alarm on your watch, phone or other digital device.
  • Use an online seizure diary or text message system (Texting 4 Control) to send you reminders of when to take medicines.
  • Write down any missed doses in your seizure diary. Share this with your health care provider at each visit.

There are different ways that medicines can affect the brain to stop seizures. In general, seizure medicines make the brain less likely to have seizures by lowering the excitability of brain cells that cause seizures.

  • The exact way that Epidiolex works to control seizures is unknown. Scientists believe Epidiolex works in more than one way.
  • Epidiolex may inhibit or slow down the way messages or signals are sent in the brain. It may change calcium levels in brain cells that are important for sending messages or signals between cells. The medicine may also decrease inflammation in the brain.
  • Researchers continue to study how cannabidiol works to help stop seizures.
  • After a medicine is swallowed, it is absorbed into the bloodstream and travels through the body and to the brain.
  • The way the body metabolizes or breaks down a medicine affects how often it must be taken.
  • Epidiolex is broken down primarily in the liver and the gut. It is cleared from the body through the feces and in a small amount through urine.

Epidiolex has been tested in people with Lennox-Gastaut (LGS) and Dravet Syndrome (DS).

  • In controlled trials in people with LGS (age 2 to 55 years), the number of drop seizures (atonic, tonic, or tonic-clonic seizures) decreased significantly from baseline for people taking 10 mg per kg per day and 20 mg per kg per day. Improvements were also seen in non-drop seizures.
  • In trials of 120 people with DS (age 2 to 18 years), the average (median) decrease in number of convulsive seizures was significantly greater for people taking 20 mg per kg per day (39% decrease) than for people taking placebo (13% decrease).

Call your health care provider if side effects occur that bother you. These may go away on their own or the dose of medicine may need to be changed. Sometimes side effects mean that you don’t tolerate the medicine and the medicine may need to be stopped. Don’t stop taking any medicine suddenly on your own.

  • Sleepiness
  • Decreased appetite
  • Diarrhea
  • Increase in liver enzymes
  • Rash
  • Sleep problems
  • Infections

Since Epidiolex may make some people sleepy, do not drive, use heavy equipment or do other dangerous activities until you know how Epidiolex affects you. People who are not seizure free also may not drive due to legal restrictions. Talk to your doctor about your seizure control, medicines, and ability to drive.

Serious side effects of Epidiolex are rare. It is important to be aware of possible reactions and what to do if they happen. Only a very small number of people have died from them.

  • Read the package insert for a complete list of all reactions to Epidiolex.
  • Call your provider’s office right away if any of these problems occur.

Allergic or hypersensitivity reactions: Tell your provider if you develop any redness, itching, rash, or swelling after starting Epidiolex. These may need treatment or the drug may be stopped.

  • Epidiolex should not be given to anyone with a prior reaction or sensitivity to cannabidiol or any of the other ingredients in the product. Sesame seed oil is present in Epidiolex.

Liver problems: Increases in liver function can be seen on blood tests in some people taking Epidiolex, especially people who may also be taking valproate (also called valproic acid or sodium valproate). It has also been seen in people taking clobazam with Epidiolex.

  • Increases in the liver function tests were usually seen in the first two months of starting the drug. The changes can be seen months later however, especially if a person also takes valproate.
  • In 1 out of 3 people the blood tests returned to normal without any changes in medicine. In other people, the problems went away when Epidiolex was stopped or the dose of valproate or Epidiolex was lowered.

Monitoring for liver function: Blood tests for liver function should be done before starting Epidiolex and after taking it for 1, 3 and 6 months. Talk to your health care provider about when to have these done.

Some symptoms of liver problems may include:

  • Black or pale color of bowel movements
  • Loss of appetite
  • Nausea, upset stomach, vomiting
  • Stomach pain
  • Tired
  • Yellow eyes or skin
  • Dark urine

Tell your health care provider right away if you notice any of these problems. Do not stop taking Epidiolex or any seizure medicine without your doctor’s advice.

Somnolence and Sedation: Some people taking Epidiolex may be unusually tired, sleepy or sedated. In controlled trials, these symptoms were seen in 1 out of 3 people taking the drug compared to 1 out of 10 people taking a placebo (inactive pill).

  • Sleepiness and sedation happened more often in people also taking clobazam (Onfi).
  • The symptoms were seen early when the medicine was started and tended to improve over time.
  • Other medicines that cause sedation or sleepiness or using alcohol could make this worse in people taking Epidiolex.
  • Talk to your health care provider if sleepiness happens and if you are taking clobazam (Onfi) or other substances that cause sleepiness.

Suicidal thoughts and behavior: In 2008, the Food and Drug Administration (FDA) reviewed data from drug studies that showed a possible relationship between many seizure medicines and suicidal thoughts and behavior. Together, these thoughts and behavior are called suicidality. According to the FDA’s Alert, among the patients with epilepsy in these drug studies, more had symptoms of suicidality than people taking a placebo or inactive substance – 3.5 of 1,000 people taking a seizure medicine had suicidality compared to 1 of 1,000 people taking a placebo.

  • Taking seizure medicines may increase the risk of having suicidal thoughts or actions.
  • Do not make any changes to the medicines without first talking to your prescribing health care provider.
  • Pay close attention to any day-to-day changes in mood, behavior and actions. These changes can happen very quickly so it is important to be mindful of any sudden differences.
  • Be aware of common warning signs that might be a signal for risk of suicide. Some of these are:
    • Talking or thinking about wanting to hurt yourself or end your life
    • Withdrawing from friends and family
    • Becoming depressed or having your depression get worse
    • Becoming preoccupied with death and dying
    • Giving away prized possessions
  • Contact your health care provider before stopping any seizure medicine. This could possibly lead to worsening of seizure and mood.

Withdrawal of seizure medicines: Epidiolex, just like any seizure medicine, should be withdrawn slowly when it is being stopped. Stopping Epidiolex or any seizure medicine suddenly can lead to more seizures and life-threatening status epilepticus.

  • If Epidiolex needs to be stopped quicker due to another problem, follow your doctor’s advice on how to make changes.

Some people taking Epidiolex and valproic acid or valproate (Depakene or Depakote) or clobazam (Onfi) have had an increase in liver enzymes.

  • Liver tests need to be checked and the dose of one of these medicines may need to be changed. Some people may not be able to take Epidiolex if this happens.

Epidiolex appears to affect a byproduct or metabolite of clobazam (Onfi). This may increase side effects of clobazam, such as excessive sleepiness or sedation.

  • Talk to your provider if taking clobazam and Epidiolex together and watch for changes in side effects. The dose of one or both of the medicines may need to be changed.

Using alcohol and other products that depress the central nervous system or brain activity (CNS depressants) while taking Epidiolex can increase sleepiness or sedation.

Epidiolex could affect some other medicines that are broken down or metabolized by the liver.

  • Tell your health care provider and pharmacist all the prescription and over the counter medicines that you take.
  • Report any changes in symptoms or side effects to your health care team.

Do not take Epidiolex if you are allergic or have a history of reactions to cannabidiol or any of the ingredients in this medicine (such as dehydrated alcohol, sesame seed oil, strawberry flavor, sucralose).

Do not use Epidiolex for other reasons or if not prescribed by a licensed health care provider.

Do not give Epidiolex to other people, even if they have similar symptoms.

  • Epidiolex has been studied in children 2 years of age and older for safety and how well it works to control seizures. The safety and effectiveness in children under 2 years old is not known.
  • The dose of Epidiolex that is prescribed is based on a person’s weight. Tell your health care providers if weight changes as the dose of medicine may need to be adjusted.

Taking medication during pregnancy is a common concern for women. Most medicines carry some risk, but the extent of risk is often unknown.

Effects of Epidiolex during pregnancy: There are no adequate data on the developmental risks of Epidiolex on a baby when taken by a woman during pregnancy. Based on research in animals, Epidiolex may cause harm to a baby when the mother uses this medicine during pregnancy.

  • All women who take seizure medicines and are able to become pregnant should take at least 0.4 mg (400 mcg) of folic acid or folate daily to help prevent birth defects (such as neural tube defects) in a child.
  • Women at high risk of having a child with a birth defect (such as those with a history of a birth defect in a prior pregnancy or taking certain seizure medicines) may be asked to take a higher dose, for example 4 mg (4,000 mcg) of folic acid daily before and during pregnancy.
  • Talk to your doctor about other possible risks to your unborn child. Ask about the risks of using the medicine during pregnancy and the risks of seizures.

Seizures during pregnancy: Some women may have more seizures during pregnancy, because of hormone changes and how seizure medicine is handled by your body. Blood levels of seizure medicine may need to be checked more regularly during pregnancy so the dose can be adjusted if needed.

Women who are pregnant or are thinking of becoming pregnant, should consider contacting the North American Antiepileptic Drug (NAAED) Pregnancy Registry at 1-888-233-2334 or visiting www.aedpregnancyregistry.org. This and other registries monitor pregnancy outcomes in women taking seizure medicines during pregnancy.

Breastfeeding: There is no information about Epidiolex or its breakdown products being present in breastmilk or the effects on milk production. With most seizure medicines, the amount of medicine the baby is exposed to while breastfeeding is less than during pregnancy. If you want to breastfeed your baby, check with your health care team about the best approach.

Contraception: There is no information about the use of Epidiolex when a woman is taking a hormonal form of birth control. Some other seizure medicines can make certain forms of birth control less effective.

  • Tell your health care team and pharmacist if you are taking hormonal birth control such as the pill, injection, or patch.
  • Ask what form of birth control would be best if you are also taking Epidiolex.

Epidiolex has not been tested in older adults, thus the use of this medicine in seniors is unknown.

  • Older adults may be more sensitive than younger adults to medicines and their side effects.
  • Other medical problems (such as changes in liver or kidney function) may affect the dose of medicine prescribed.
  • Older adults may also be on other medicines that can interact with each other and cause more side effects.
  • In general, lower doses of seizure medicines are given to older adults and the dose is increased more slowly.

Epidiolex and Drug Testing

People who take Epidiolex may test positive for cannabis drug screens. Tell the person giving the drug test that you are taking Epidiolex for a medical reason.

In the United States, companies that manufacture medicines are required to publish a “package insert.” This document gives detailed information about the medicine and what you should know if you are taking it.

Cannabidiol oral solution Epidiolex ® (EH-peh_DYE-oh-lex) oral solution CV is the brand name for the cannabidiol oral solution, also referred to as CBD, from Greenwich Biosciences. The name or