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Best CBD Oil for Pain: The Ultimate Self-Care Guide (2021 Update)

How do you choose the right CBD oil for pain relief?

How do you choose the right CBD oil for pain relief? Royal CBD

Finding the best CBD oil for pain can be time-consuming, not to mention the money and hard work involved with classic trial-and-error. If you want to save both time and money on buying CBD oil, you can use our experience and transfer those resources to one of the three brands we recommend.

Top 4 Best CBD Oil Products for Pain Relief

CBD oil can significantly improve your wellbeing as long as you’re using the right product. Whether you’re dealing with pain, anxiety , or sleeplessness , quality is paramount to your experience.

But how do you choose the right CBD oil for pain relief?

We’ll cover that later in the article, but first, let’s introduce you to some of the best CBD oils we’ve ever tried. Each of these products have been carefully reviewed to make sure you find the best CBD oil for your type of pain.

1. Royal CBD: Best Full Spectrum CBD Oil

Royal CBD

Royal CBD. Royal CBD

Royal CBD oil is made from organic ingredients. The company uses organic hemp plants and supercritical extraction for its products, resulting in pure and potent extracts.

Even its packaging is processed in a sustainable way, so if you value ethical consumerism, then Royal CBD should be high on your list.

When it comes to the quality of Royal CBD oil, “premium” is the right way to describe it.

The oil is suspended in organic MCT oil for improved absorption and additional benefits for the heart and brain from the oil’s essential fatty acids.

Royal CBD oil is available in four strengths: 250 mg, 500 mg, 1000 mg and 2500 mg. You can choose between the natural, citrus and mint flavors.

This is a full-spectrum extract, so you’re getting the entire range of non-psychoactive cannabinoids, as well as trace levels of THC (below 0.3%), terpenes and other compounds from hemp.

2. Gold Bee – Best Organic CBD Oil

GoldBee

Gold Bee. GoldBee

Similar to Royal CBD, Gold Bee specializes in full-spectrum CBD oil from all-organic ingredients. The company combines two superfoods: CBD-rich plants from Colorado and organic honey from Brazilian Rainforest. The Gold Bee CBD oil is a full-spectrum product, so you’re getting the synergistic effects of all cannabinoids and terpenes from the original plant. The maximum potency here is 1200 mg, which translates to 40 mg in each milliliter.

Full-spectrum extracts are generally considered more effective when it comes to easing physical discomfort due to the aforementioned synergy. Suspension in hemp seed oil makes the CBD more available for the body. If you’re not a fan of natural CBD oils, you can try the Kiwi option, which is flavored with honey. Gold Bee also offers high-potency CBD capsules (up to 40 mg per capsule) and delicious honey sticks — a great product selection for a brand with a Bee in its logo.

3. CBDPure – Runner Up

CBDPure

CBDPure is one of the most transparent brands on the market. The company broadly explains every stage of making its CBD oil and has lab reports for each batch of product.

The golden color of the oil is a good indicator of its quality—it means that someone did a good job while filtering the extract from the excess chlorophyll and plant material.

The oil has an earthy scent, which is typical for full-spectrum hemp extracts, but it tastes surprisingly good for one.

It’s not the most potent oil out there. You can choose between three strengths: 100 mg, 300 mg and 600 mg. The lowest potency offers 3.3 mg of CBD per serving, which may be good for very mild pain, or if you’re using CBD oil for the first time.

CBDPure sells both full-spectrum and pure (THC-free) oil. The pure version is better for those who want to benefit from CBD without any THC in their system. Some people just want to err on the side of caution, whereas others can’t use full-spectrum products because they’re subject to regular drug tests at work.

4. NuLeaf Naturals

NuLeaf Naturals

NuLeaf Naturals. NuLeaf Naturals

NuLeaf Naturals has been selling premium CBD oil for over five years now, and surprisingly, the company decided not to extend its line of products.

NuLeaf only sells traditional CBD oil drops—and nothing else.

If you’re looking for a wider product selection, we suggest that you stick with Royal CBD, but if you’re aiming for a full-spectrum CBD oil formulated to perfection, then this company is one of the most reputable manufacturers in the industry.

NuLeaf Naturals offers its CBD oil in five bottle sizes:

  • 5 mL — 240 mg of CBD;
  • 15 mL — 725 mg of CBD;
  • 30 mL — 1450 mg of CBD;
  • 50 mL — 2425 mg of CBD; and
  • 100 mL — 4850 mg of CBD.

The potency of this oil doesn’t change with the bottle’s size, so it’s a good option for people who know their effective dosage and are looking for several months worth of supply.

The only downside about NuLeaf Naturals—aside from the limited product lineup—is that these oils are priced higher than other brands in this ranking while offering similar quality.

What Is CBD Oil?

CBD oil is a natural alternative to over-the-counter supplements—and a modern panacea for a wide range of health concerns. Some people use it to relax and ease their mind after a tense day, whereas others take CBD oil for chronic conditions involving inflammation, pain and poor mood.

CBD is extracted from the flowers of mature cannabis flowers and then processed into an oily extract. The extraction process, as well as the solvents involved, can heavily impact the quality of the end product.

The way CBD produces its effects is still unclear to scientists. However, most experts agree that CBD modulates the endocannabinoid system (ECS), without directly stimulating cannabinoid receptors, in a similar way that THC does.

THC binds to cannabinoid receptors in the brain, mimicking the actions of a similarly built chemical produced by the brain (anandamide), hence the psychoactive effects.

CBD, on the other hand, affects dozens of pathways throughout the human body. It may change the way we experience anxiety, inflammation and pain.

Most Notable Studies on CBD and Pain

CBD oil has a plethora of health benefits, and you can probably name a few right away. It’s considered to be one of the most beneficial cannabinoids in the cannabis plant. Let’s see what studies say about using CBD oil for pain management.

A 2008 review of the existing studies on CBD in relieving chronic pain concluded that CBD was effective in managing pain without causing unwanted reactions.

In 2007, a double-blind controlled study found that CBD can assist patients suffering from neuropathic pain.

Finally, a 2016 study showed positive correlation between the use of CBD and reduced inflammation in arthritis patients. In this study, the researchers applied CBD topical to rats for four consecutive days.

The study concluded that rats who were given CBD showed lower levels of pain and inflammation in the affected areas.

How to Use CBD Oil for Pain

Full-spectrum CBD oil is considered to be the most effective form because it features all compounds that are naturally found in the plant. These include not only cannabinoids, bu also terpenes and essential oils. Studies have found full-spectrum extracts to be more effective at treating pain and inflammation than their single-molecule counterparts.

You can buy CBD oil in a bottle with a dropper. The dropper allows you to measure just the right amount of oil and transfer it under the tongue, where you have to hold it for about 60 seconds before swallowing.

The effects of CBD oil should come within 20 minutes, with benefits lasting for four to six hours, depending on your dosage and metabolism.

There are no strict dosage guidelines to follow when it comes to using CBD oil for pain. That’s because everyone reacts differently to CBD oil.

For starters, we suggest that you determine the severity of pain.

Decide what kind of pain is “manageable” for you, and try to level it down to that point.

For low pain, it’s a good idea to start with 5–10 mg of CBD per day. For medium to high pain, the dosage ranges between 20–100 mg. For more convenient usage, you can also consider choosing high potency CBD edibles .

Why should you go low and slow?

Because some people are very sensitive to cannabis compounds. There are individuals who benefit from ridiculously low doses. Lower increments allow for more accurate dosing, making sure you won’t experience any side effects aside from its benefits.

CBD Oil or CBD Cream: Which One Should I Use for Pain?

Having pain on your leg may lead you to think that applying CBD cream on the affected area will yield better results than swallowing CBD oil.

Well, this isn’t actually the case.

Using CBD topicals on painful areas is a good option if the pain is shallow. Using CBD topicals on painful areas is a good option if the pain is shallow. CBD topical creams only work on anatomical structures that are located up to one-centimeter under the skin.

And when you struggle with joint inflammation or muscle soreness, the problem is probably more complex than that.

CBD topicals generally call for a liberal splash over the affected area. If you have a generous hand with creams, there’s a chance that some of it will penetrate the skin down to your muscles.

It doesn’t mean that you shouldn’t use topicals at all. In fact, they make for a great addition to CBD oil because they approach the problem from a slightly different angle.

How to Determine a High Quality CBD Oil

If you’re trying a new product for your well-being or symptoms for the first time, you want to make sure it’s the highest quality possible.

Here are the most important buying criteria:

The Source

The source of CBD is paramount to the quality of the end product. Hemp plants are bioaccumulators, meaning they absorb every substance from the soil they were planted in—including both the bad and the good substances.

When grown in fertile soil, without using pesticides and other toxic chemicals, hemp will be high in CBD and nutrients. It will also be free of contaminants. That’s why it’s important to choose companies that make their products from organic hemp.

Potency

This is the second-most important factor to consider when buying CBD oil for pain. Potency tells you how much CBD there is in the bottle, as well as in each milliliter of the oil.

Look for brands that sell CBD oil in a wide range of concentrations. That way, you’ll be able to choose the most efficient option, both in terms of the effects and your budget.

Please remember that higher potency doesn’t mean the oil will work better for you. As noted, some people benefit from low doses, so if a 250 mg bottle does the trick for your pain, there’s no need to look for stronger options.

Extraction Method

Extraction means pulling CBD and other compounds from the plant material using some kind of solvent. The golden standard for making CBD products is CO2 extraction.

CO2 is used as a solvent that changes its state from gas to liquid, penetrating the plant and extracting cannabinoids from it. Eventually, the CO2 will dissipate, leaving behind an oily, viscous extract.

Alternative extraction methods include olive oil or alcohol (tinctures). Steer clear of CBD oil that was made with butane, as this solvent is difficult to work with and may leave toxic residue at the bottom of your oil if handled improperly.

Third-Party Testing

CBD companies can send samples of their products for content analysis to independent laboratories.

These laboratories check the potency of CBD and look for common contaminants in the end products. Before CBD oil makes it on the shelves, the company should ensure that there are no inconsistencies in the CBD concentration and purity levels.

Third-party testing is the only way to confirm that you’re getting exactly what you’re buying. Most reputable companies display lab reports on their websites.

Where to Buy CBD Oil

It’s quite easy to find CBD oil for sale these days because the market is growing and new CBD companies are popping up each month. You can either get your CBD oil online or buy it from one of the local dispensaries in your state.

We don’t recommend head shops, food stores or other brick-and-mortar stores, as they usually carry overpriced products whose quality leaves a lot to be desired.

Buying CBD oil online gives you access to a wider range of products, attractive seasonal deals and other perks for registered customers

You can easily verify the credibility of your potential vendor by simply reading how they manufacture their products, checking the Certificates of Analysis, or looking at reviews from other customers and ratings at CBD-dedicated websites.

Potential Side Effects of CBD Oil

Your safety should be your top priority, so it’s important that you understand the possible risk of taking CBD oil.

The good thing is that CBD oil doesn’t really have serious side effects. The World Health Organization has acknowledged it as a safe product that doesn’t cause dependency.

The most common reaction to CBD oil is the sensation of dryness in the mouth. This is typical to all cannabis products and results from the effect of cannabinoids on salivation. You can avoid this side effect by staying well hydrated after applying CBD oil.

Experiencing dizziness due to lowered blood pressure is also common among CBD users. At extremely high doses, CBD can cause diarrhea and nausea. It happens when you take more than your body can handle, so you simply flush the excess oil out of your system.

Having a dry mouth can also temporarily suppress your appetite, but these effects should pass over time.

Last but not least, there are a couple of medications that can negatively interact with CBD.

For example, CBD is a blood-thinning agent. By lowering your blood pressure, CBD oil can result in harmful levels of hypotension.

If you take any prescription drugs, it’s best to consult with a doctor prior to buying any CBD product.

Final Thoughts on Using CBD Oil for Pain

CBD oil comes with a myriad of health benefits, including relief from different types and levels of pain. The lion’s share of these benefits result from CBD’s interaction with our endocannabinoid system.

By altering pain transmission from nerves to the brain, CBD can help people manage pain and improve their quality of life in a safe and natural way. However, it’s important that you only use high-quality products that come from reputable manufacturers. Only then will you be able to get the most out of CBD’s analgesic properties.

Best CBD Oil for Pain: The Ultimate Self-Care Guide (2021 Update)

We hope that this guide has helped you get a better understanding of CBD products. Feel free to use our recommendations and let us know how CBD oil helped you with your pain!

What’s the best CBD oil for dealing with different types of pain? How does using CBD oil for pain compare to traditional remedies? Find these out and more in our ultimate buying guide.

10 Best CBD Oil for Arthritis & Joint Pain – 2021 CBD Reviews

Best CBD Oil For Arthritis & Joint Pain

Many arthritis sufferers use CBD as an alternative remedy for easing joint pain. We’ve put together a list of the best CBD oil for arthritis and a guide to help you get the most out of CBD.

Arthritis is a common condition characterized by joint pain and inflammation. The United States witnessed a significant increase in the prevalence of arthritis in recent years. Standard treatments typically focus on pain relief but aren’t always effective and can cause notable side effects.

As a result, more and more people are opting for safe, natural options such as CBD oil. Still, with so many products available and a lack of regulation, finding a high-quality CBD product can be difficult.

That’s why we researched and compared numerous leading brands to find the best CBD oil for arthritis as well as the best CBD cream.

Here’s our list of the top 10 CBD oils and creams for this debilitating condition, based on the formula, potency, hemp source, third-party testing, pricing, and other factors.

Top 10 Best CBD Oil For Arthritis 2021

  • Spruce – CBD For Arthritis
  • CBDfx – Best Formula
  • CBDpure – Best for Beginners
  • Medterra – Best Pure CBD
  • Joy Organics – Best THC-Free
  • CBDistillery – Best Potency
  • Endoca – Best Quality Control
  • Charlotte’s Web – Best Topical
  • NuLeaf Naturals – Best Full-Spectrum
  • Lazarus Naturals – Best Value

CBD for Arthritis

CBD oil and topical CBD products are an increasingly popular option for arthritis sufferers. Although more research is needed, early studies [1] indicate that CBD and other cannabinoids may relieve the pain and inflammation involved in arthritis. Some of the suitable CBD oil for pain can be found here.

This means CBD can help with symptom relief in common types of arthritis, including osteoarthritis and rheumatoid arthritis.

Better yet, there’s some evidence that CBD may have a positive effect on the inflammation that causes some types of arthritis, which means it may help the condition directly.

CBD can also offer indirect benefits for arthritis sufferers, such as improving sleep and mood-related issues.

In comparison, prescription drugs typically only focus on pain relief instead of improving the root cause of certain types of arthritis. They can also cause significant side effects and other issues such as withdrawal in the case of opioids..

Take Spruce CBD

Spruce CBD

Why is it better?

  • Comprehensive third-party testing
  • Family-run business
  • High-quality, unique strain of hemp

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The Lineup At A Glance

Best Formula

  • Unique anti-inflammatory formula
  • Comprehensive third-party testing
  • High-quality Kentucky hemp

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Most Natural

  • Full-spectrum formula rich in minor cannabinoids
  • Comprehensive third-party testing
  • Unflavored and mixed with hemp seed oil

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Best Pure CBD

  • Pure CBD isolate formula
  • Exceptionally low prices
  • U.S. Hemp Authority Certified

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Best THC-Free

  • THC-free, broad-spectrum formula
  • Comprehensive third-party testing
  • High-quality Colorado hemp

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Best Full-Spectrum

  • High-quality full-spectrum formula
  • Established, reputable brand
  • Comprehensive third-party testing

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Best Potency

  • Very high potency available
  • U.S. Hemp Authority Certified
  • High-quality Colorado hemp
  • Comprehensive third-party testing

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Best Quality Control

  • High-quality full-spectrum formula
  • Grows its own hemp
  • Comprehensive third-party and in-house testing

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Best Topical

  • Special arthritis formula
  • U.S. Hemp Authority Certified
  • Comprehensive third-party testing

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Best Value

  • Exceptionally low prices
  • Large discounts for veterans
  • Comprehensive third-party testing

10 Best CBD Oil for Arthritis Reviews (& Cream)

Spruce CBD

Take Spruce CBD

For those who don’t mind paying a little more for high-quality CBD from a family-run company with hundreds of satisfied customers, Spruce CBD is a solid pick.

  • Comprehensive third-party testing
  • Family-run business
  • High-quality, unique strain of American hemp
  • Costs more than average
  • Only two potencies

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Spruce CBD was founded in North Carolina in 2018. The company stands out for being a relatively small, family-run business and having hundreds of satisfied customer reviews.

Spruce sources its CBD products from a 200-year-old strain of hemp grown organically in Kentucky and North Carolina. It uses a time-tested alcohol extraction process to create full-spectrum products rich in all of hemp’s beneficial components.

The company also posts detailed third-party test reports for everyone to see. Besides working well on adults, Spruce CBD is also safe for kids, which makes it one of the most popular choice on the market.

Spruce’s CBD oil comes in two strengths: regular, with 25 mg CBD per ml and 750 mg total, and high-strength, with 80 mg/ml and 2400 mg CBD in total. Both tinctures are formulated with hemp seed oil and the regular version is also flavored with peppermint.

The 2400 mg tincture may be particularly suited for arthritis thanks to its high potency.

CBDPure CBD Oil

CBDPure CBD Oil_1

Some people prefer CBD oils that are as close to natural as possible. In that case, CBDPure is a decent option.

  • Full-spectrum formula rich in minor cannabinoids
  • Comprehensive third-party testing
  • Unflavored and mixed with hemp seed oil
  • 90-day satisfaction guarantee
  • Basic website that lacks detailed info
  • Low CBD potency

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Washington’s CBDPure has been around since 2016. The company offers a simple yet effective lineup of full-spectrum CBD oil, capsules, and cream sourced from organic hemp grown in Colorado and Washington.

As demonstrated by the company’s third-party lab reports, the full-spectrum extract used in its products contains significant amounts of minor cannabinoids like CBC, CBDV, and CBG.

That’s a sign of a high-quality full-spectrum product since these compounds add to the beneficial effects of CBD.

CBDPure offers a 60 ml CBD oil containing full-spectrum CBD extract blended with hemp seed oil and no other extra ingredients. It comes in three strengths:

  • 5 mg/ml (300 mg total)
  • 10 mg/ml (600 mg total)
  • 17 mg/ml (1000 mg total)

This isn’t the most potent CBD oil on the market. However, if you’re looking for a quality low-medium potency tincture made with pure ingredients, CBDPure fits the bill. We also have details of CBDPure brand you can read here.

CBDfx CBD + CBG Wellness Tincture

CBDfx-Tincture

If you’re looking for a CBD oil designed for arthritis, CBDf’xs wellness tincture is a great choice because it contains multiple anti-inflammatory ingredients backed by evidence-based research.

  • Unique anti-inflammatory formula
  • Comprehensive third-party testing
  • High-quality Kentucky hemp
  • Four potencies
  • Lacks regular full-spectrum formulas
  • Lacks flavored options

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CBDfx is an established CBD brand out of California. It offers many different kinds of CBD products with unique formulas, flavors, and other features that make it stand out from the competition.

CBDfx sources its hemp from organic farms in Kentucky. All of its products go through extensive third-party testing to verify their potency and safety.

CBDfx’s unique take on CBD products can be seen with their wellness tincture. It contains not only CBD but also a large amount of CBG, another beneficial cannabinoid,

More importantly, this CBD oil carries two natural anti-inflammatory compounds that have been demonstrated to help with arthritis symptoms in research studies: coenzymeQ10 [2] (CoQ10)- a rat-based study and curcumin [3] study in humans.

That’s why this CBD oil is especially suitable for dealing with arthritis. It’s available in four strengths:

  • 500 mg CBD/250 mg CBG
  • 1000 mg CBD/500 mg CBG
  • 2000 mg CBD/1000 mg CBG
  • 4000 mg CBD/2000 mg CBG

Medterra CBD Oil

Medterra oil -2

Medterra is a top-tier CBD brand with competitive prices and is a particularly great option when you need pure CBD oil without any other active ingredients.

  • Pure CBD isolate formula
  • Exceptionally low prices
  • U.S. Hemp Authority Certified
  • Comprehensive third-party testing
  • No flavored options

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Founded in 2017, Medterra is a leading CBD company known for offering quality products at affordable prices. All of its offerings are completely free of THC and sourced from organic hemp cultivated in Kentucky.

Medterra publishes detailed third-party lab test reports of its products. The company is also certified by the U.S. Hemp Authority, which means it passed a strict independent audit confirming that it follows strict hemp manufacturing standards.

Some people prefer to use CBD oil containing pure CBD (also called isolate) for arthritis and other conditions. In that case, Medterra is a great choice. It’s CBD oil comes in three strengths:

  • 17 mg/ml (500 mg total)
  • 33 mg/ml (1000 mg total)
  • 100 mg/ml (3000 mg total)

It has a straightforward formula combining CBD isolate with coconut MCT oil.

Joy Organics cBD Oil

Joy Organics CBD Oil

Joy Organics is a good choice when you need CBD oil that doesn’t contain any THC but still provides all of the cannabinoids, terpenes, and other beneficial hemp compounds alongside CBD.

  • THC-free, broad-spectrum formula
  • Comprehensive third-party testing
  • High-quality Colorado hemp
  • Four potencies and flavors
  • Low levels of minor cannabinoids
  • Lacks high-potency options

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Joy Organics is a family-run CBD company out of Fort Collins, Colorado. It differentiates itself by offering only broad-spectrum CBD products.

Broad-spectrum CBD is a type of whole-plant hemp extract that contains all of the plant’s beneficial cannabinoids, terpenes, flavonoids, and other ingredients, but with zero THC.

In that sense, it’s ideal for those who want to get the most out of hemp while completely avoiding THC.

Joy Organics’ products are derived from organic Colorado-grown hemp. They’re comprehensively tested by a third-party lab to make it easy to verify their potency and safety. It is also found to be the best CBD for high blood pressure patients

Joy Organics offers broad-spectrum CBD oil in four strengths:

  • 7.5 mg/ml (225 mg total)
  • 15 mg/ml (450 mg total)
  • 30 mg/ml (900 mg total)
  • 45 mg/ml (1350 mg total)

It uses virgin olive oil as the carrier oil and has four flavor options — natural, tranquil mint, summer lemon, and orange bliss.

NuLeaf Naturals Full-Spectrum CBD Oil

NuLeaf Naturals CBD Oil

NuLeaf Naturals is one of the most respected names in the U.S. CBD industry, known particularly for its high-quality full-spectrum CBD oil tinctures.

  • High-quality full-spectrum formula
  • Established, reputable brand
  • Comprehensive third-party testing
  • High-quality Colorado hemp
  • Free shipping
  • Lacks flavored options
  • Only one potency

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Founded in 2014 in Colorado, NuLeaf Naturals is one of the leading CBD brands in the country. Until recently, NuLeaf sold only one type of CBD product — full-spectrum CBD oil — which highlights the company’s unrivaled expertise and a strong reputation.

NuLeaf uses organic Colorado-grown hemp-extracted with CO2 to make its products, which undergo comprehensive third-party testing for cannabinoid levels and contaminants.

The test results confirm that NuLeaf’s full-spectrum CBD extracts contain the full range of beneficial cannabinoids.

The best CBD oil for arthritis should use a potent, full-spectrum formula, and NuLeaf Naturals certainly meets that requirement.

Its CBD oil has a high potency of 60 mg per ml and comes in five bottle volumes ranging from 5 ml to 100 ml, with 300-6000 mg of CBD. It’s formulated with hemp seed oil without any added flavoring.

CBDistillery Full-Spectrum CBD Oil

CBDistillery oil_1

Many people with arthritis prefer a high-potency CBD oil for significant relief. In that case, CBDistillery is an excellent pick because it offers tinctures containing as much as 167 mg of CBD per ml.

  • Very high potency available
  • U.S. Hemp Authority Certified
  • High-quality Colorado hemp
  • Comprehensive third-party testing
  • Lacks flavored options

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One of the biggest names in the CBD industry, CBDistillery was founded in Colorado in 2016. The company offers a full range of affordable, high-quality CBD products with multiple strength options.

They’re derived from organic hemp grown in Colorado and tested by a third-party lab to confirm their potency, safety, and consistency.

Better yet, CBDistillery is certified by the U.S. Hemp Authority, an independent certification program that ensures adherence to hemp industry best practices.

The company offers four full-spectrum CBD oil strengths:

  • 17 mg per ml (500 mg total)
  • 33 mg per ml (1000 mg total)
  • 83 mg per ml (2500 mg total)
  • 167 mg per ml (5000 mg total)

This makes CBDistillery one of the best CBD oil options for people in need of a high-strength tincture for arthritis. These unflavored oils are formulated with coconut MCT oil.

Lazarus Naturals Full-Spectrum CBD Oil

lazarus naturals cbd oil-1

Lazarus Naturals is our top pick for people looking to get the most value when buying CBD oil.

  • Exceptionally low prices
  • Large discounts for veterans
  • Comprehensive third-party testing
  • Grows most of its own hemp
  • Multiple potencies, sizes, and flavors
  • Lacks extra high potency (80+ mg/ml)
  • Lacks 30 ml bottle size

Thanks to its incredibly low prices, Lazarus Naturals is one of the most popular CBD companies in the U.S. More importantly, it manages to offer these prices while maintaining an exceptional level of product quality.

Lazarus Naturals even has a 60% discount for low-income individuals, people with disabilities, and veterans.

An employee-owned company, Lazarus Naturals is one of the few brands that does all of its own manufacturing, starting with the hemp and ending with the finished product. Most of its CBD is sourced from organic hemp grown on the company farm in central Oregon.

Lazarus Naturals’ full-spectrum CBD oil is a great option for arthritis. It’s available in two strengths:

  • Regular (20 mg/ml)
  • High potency (50 mg/ml)

These oils are formulated with coconut MCT oil and come in 15 ml, 60 ml, and 120 ml bottles. You can choose from five flavors: unflavored, chocolate mint, French vanilla mocha, and Yuzu citrus.

Endoca Full-Spectrum CBD Oil & Cream

Endoca CBD Oil_1

Endoca is a respected, established CBD company known for its outstanding quality control.

  • Full-spectrum formula rich in minor cannabinoids
  • Grows and extracts its own hemp
  • Comprehensive third-party and in-house testing
  • Two formulations
  • Established, reputable brand
  • Strong earthy flavor
  • Only two potencies

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Denmark’s Endoca is one of the most respected brands in the CBD industry. The company has been around since 2010, making it one of the first to offer CBD products.

Endoca has a diligent approach; the company not only has complete control over the manufacturing process but also employs the most advanced, scientific methods available.

Endoca starts by growing hemp on its own organic, non-GMO farms in Denmark and extracting it using the industry-preferred carbon dioxide (CO2) method.

That’s why its full-spectrum extracts contain significant amounts of minor cannabinoids like CBC and CBG, which multiply the beneficial impact of CBD.

Endoca tests its plants, extracts, and finished products in its in-house lab to verify cannabinoid levels, lack of pesticides, and even the amount of terpenes, another type of beneficial active ingredient. The company then sends its products for third-party testing.

When it comes to the best CBD oil for arthritis, Endoca is a great option.

The company’s tinctures come in two potencies:

  • 30 mg/ml (medium), with 300 mg of CBD in total
  • 150 mg/ml (high), with 1500 mg of CBD in total

It’s also available in two formulations: regular and raw. The raw formula is unprocessed, which means it contains high levels of CBDa, another beneficial cannabinoid that converts into CBD when heated.

Charlotte’s Web CBDMedic Arthritis Ointment

charlotte

Charlotte’s Web is a reputable company offering one of the only dedicated topical CBD products for arthritis.

  • Special arthritis formula
  • U.S. Hemp Authority Certified
  • Comprehensive third-party testing
  • Established, respected brand
  • Third-party test results only available after purchase
  • Only one potency

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Established in 2013, Charlotte’s Web is one of the giants of the CBD industry. The company was created by the Stanley Brothers, who developed a special high-CBD strain of cannabis they called Charlotte’s Web back in 2011.

The company gets its name from Charlotte Figi, a young girl who found relief from seizures by using the Stanley Brothers’ CBD-rich cannabis strain.

Charlotte’s Web offers a wide variety of CBD products sourced from organic hemp cultivated in Colorado, Oregon, and Kentucky.

The company takes special steps to ensure strict quality control, such as testing the soil the hemp is grown in addition to comprehensive third-party testing.

That’s also why it’s certified by the U.S. Hemp Authority, which requires passing an independent audit and following stringent manufacturing standards.

Charlotte’s Web is one of the only companies that has a topical CBD product designed specifically for arthritis.

Its arthritis aches & pain relief ointment contains 200 mg of broad-spectrum (THC-free) CBD extract alongside camphor and menthol: two popular topical ingredients used to relieve pain thanks to their soothing effects. This ointment is formulated with all-natural ingredients.

CBD For Arthritis & Joint Pain

Cannabidiol (CBD) is a non-intoxicating cannabis compound that’s shown some promise in relieving the symptoms of arthritis.

Similar to its cousin tetrahydrocannabinol (THC), CBD seems to have both analgesic (pain-relieving) and anti-inflammatory [4] properties that can reduce joint pain.

Better yet, there are multiple animal studies and early human trials backing CBD’s anti-arthritic effects, as well as evidence that it might help with the underlying causes of inflammatory arthritis.

Types of Arthritis

Arthritis refers to joint pain or any type of joint disease [5] . There are many different types of arthritis but the two most common kinds are inflammatory and non-inflammatory [6] .

Non-inflammatory arthritis, also known as osteoarthritis, is the most common kind. It’s caused by the breakdown of cartilage, the protective bone padding found at the joints.

As the name implies, inflammatory arthritis involves some sort of inflammation. The most common example is rheumatoid arthritis, an autoimmune condition where your immune system mistakenly attacks its own joint tissue.

Gout is another type of inflammatory arthritis, caused by uric acid building up in the joints. Other examples include juvenile arthritis, reactive arthritis, infectious arthritis, and ankylosing spondylitis.

How CBD Works on Arthritis Pain

CBD can relieve arthritis pain by interacting with your body’s endocannabinoid system (ECS).

Charged with maintaining a delicate state of balance called homeostasis, the ECS regulates essential processes, including pain, inflammation, immune function, and pain.

The ECS consists of endocannabinoids made in your body, the cannabinoid receptors they activate, and special enzymes. CBD can interact with the ECS by blocking the effects [7] of an enzyme that breaks down your endocannabinoids, supporting their beneficial effects.

Additionally, animal studies have shown that CBD may affect other systems involved in controlling pain and inflammation, such as TRPV [8] , PPARγ [9] , and adenosine [10] receptors, and the (NF)-κB [11] pathway.

Benefits of CBD for Arthritis Patients

There’s reason to be excited about CBD because it can help with arthritis on multiple fronts.

To begin with, CBD can improve not only chronic pain but other symptoms associated with arthritis, such as difficulty sleeping and a low mood.

Better yet, CBD may be able to address the underlying inflammation involved in inflammatory types of arthritis.

Here are some of the key research findings:

  • A study of a synthetic transdermal CBD gel [12] in people with knee osteoarthritis found that some participants experienced a significant reduction in pain with men benefitting more than women.
  • A study of Sativex (a drug containing a 1:1 ratio of THC to CBD) in rheumatoid arthritis sufferers found that it improved joint pain and sleep [13]
  • A case report [14] reported that a 50-year-old woman with rheumatoid arthritis and two other autoimmune disorders improved her pain, mobility, mood, and inflammation by using CBD oil
  • Studies in mice have shown that CBD can reduce pain and nerve damage in osteoarthritis [15] and pain and inflammation in rheumatoid arthritis [16]

Is Cannabidiol safe? Side Effects and Safety

Although CBD can cause some side effects, it’s considered a well-tolerated compound with a good safety profile [17] .

The possible side effects of CBD [18] reported in research include:

  • Tiredness and drowsiness
  • Diarrhea and nausea
  • Dry mouth
  • Low blood pressure
  • Lightheadedness
  • Changes in appetite or weight

However, researchers note that most of these effects were minor and only occurred when taking pure CBD in high doses, such as 300 mg or higher.

Since most people use much smaller amounts and often go with whole-plant products containing many other active compounds, your chances of experiencing side effects from CBD are small.

Topical CBD products are even less likely to produce side effects because it’s difficult for CBD to absorb deep enough into the skin to reach your blood vessels.

How Do I Use CBD To Manage Arthritis Pain?

There are multiple ways to use CBD for arthritis pain.

Roughly speaking, you can take CBD internally, which will produce body-wide effects, or use it externally, which will only work in the area where it’s applied and is best suited for arthritis pain.

You’ll also need to figure out the right CBD dosage for yourself.

Using CBD Internally (CBD Oil, Capsules, Edibles, and Vaping)

The most common method of using CBD is sublingual — putting drops of CBD oil under your tongue. This method bypasses the digestive tract by avoiding stomach acid and liver degradation, which greatly enhances the blood levels and the effectiveness of CBD.

It also produces systemic effects, which is especially important for rheumatoid and other inflammatory types of arthritis. If you could only choose one product for arthritis, we’d definitely recommend CBD oil.

You can also use CBD capsules, edibles, and other oral products, but they’re not as effective as the sublingual route because they have low oral bioavailability [19] , which means that only a small percentage of the CBD you take in this form reaches the blood.

Another option is to vape CBD, which will produce instant effects and has similar or better [20] absorption than CBD oil. However, it also wears off much faster. And vaping has other potential risks to the lung tissue.

Using CBD Externally (Creams and Other Topical Products)

The second major option for arthritis is to apply CBD directly to the skin around the affected joints in the form of creams and other topical products.

This is arguably the best choice if you’re primarily looking for pain relief because it will work only where you applied it.

In any case, it may be ideal to use both external and internal routes together, such as CBD oil and a CBD-infused cream.

CBD Dosage for Arthritis

There isn’t one dosage of CBD that will work in all cases. We’re all different and the right amount of CBD to take will depend on how much you weigh, your unique genetics, the severity of your arthritis, and the kind of CBD product you’re taking.

Consequently, the best approach to figuring out your CBD dosage is to “start low and go slow” [21] as suggested by health experts. That means taking a small dose (10-15 mg), seeing how you feel over the next few hours, and gradually increasing the dose over time.

Do this until you start experiencing relief and stick to that amount.

Frequently Asked Questions

Cannabidiol or CBD t is one of the many naturally-occurring phytocannabinoids found in cannabis. CBD has many potential health benefits thanks to its interaction with your endocannabinoid system.

No, CBD cannot get you high because it doesn’t have any intoxicating properties.

According to numerous studies, CBD is a safe compound with mostly mild side effects.

CBD oil is a dietary supplement made up of hemp-derived CBD extract dissolved in a plant oil like olive oil or coconut MCT oil. You use it by applying drops of oil under the tongue so it can absorb directly into the blood and bypass the digestive system.

There’s no one-size-fits-all dose of CBD for arthritis. Start with a small dose (10-15 mg), pay attention to the effects for the next few hours, and increase as needed.

Generally speaking, CBD oil is the best overall choice. However, topical CBD products may work better if you’re only interested in pain relief. Still, you’ll get the best results from using both methods together.

Health Canal avoids using tertiary references. We have strict sourcing guidelines and rely on peer-reviewed studies, academic researches from medical associations and institutions. To ensure the accuracy of articles in Health Canal, you can read more about the editorial process here

  1. Charles A Gusho & Tannor Court. 2020. Gusho CA, Court T. Cannabidiol: A Brief Review of Its Therapeutic and Pharmacologic Efficacy in the Management of Joint Disease. Cureus. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176325/
  2. Lee J, Hong YS, Jeong JH, et al. 2013. Coenzyme Q10 Ameliorates Pain and Cartilage Degradation in a Rat Model of Osteoarthritis by Regulating Nitric Oxide and Inflammatory Cytokines. Rakonczay Z, ed. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718733/
  3. Shep D, Khanwelkar C, Gade P, Karad S. 2019. Safety and efficacy of curcumin versus diclofenac in knee osteoarthritis: a randomized open-label parallel-arm study, 20(1) Trials.‌ Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460672/
  4. ‌Russo, E. 2008. Cannabinoids in the management of difficult to treat pain. Therapeutics and Clinical Risk Management, Volume 4, 245–259. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2503660/
  5. Anon. 2020. Frequently Asked Questions (FAQs) about Arthritis. Available from: https://www.cdc.gov/arthritis/basics/faqs.htm
  6. Shayan Senthelal, Li, J., Amandeep Goyal, Pankaj Bansal and Thomas, M.A. 2020. Arthritis. Nih.gov. Available from: https://www.ncbi.nlm.nih.gov/books/NBK518992/.
  7. Leweke, F.M., Piomelli, D., Pahlisch, F., Muhl, D., Gerth, C.W., Hoyer, C., Klosterkötter, J., Hellmich, M. and Koethe, D. 2012. Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia. Translational Psychiatry, 2(3), pp.e94–e94. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3316151/.
  8. Costa, B., Giagnoni, G., Franke, C., Trovato, A.E. and Colleoni, M. 2004. Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation. British Journal of Pharmacology, 143(2), 247–250. Available from: https://pubmed.ncbi.nlm.nih.gov/15313881/.
  9. O’Sullivan, S.E. 2016. An update on PPAR activation by cannabinoids. British Journal of Pharmacology, 173(12), 1899–1910. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882496/.
  10. Mecha, M., Feliú, A., Iñigo, P.M., Mestre, L., Carrillo-Salinas, F.J. and Guaza, C. 2013. Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: A role for A2A receptors. Neurobiology of Disease, 59, 141–150. Available from: https://pubmed.ncbi.nlm.nih.gov/23851307/.
  11. Kozela, E., Pietr, M., Juknat, A., Rimmerman, N., Levy, R. and Vogel, Z. 2009. Cannabinoids Δ9-Tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-activated NF-κB and Interferon-β/STAT Proinflammatory Pathways in BV-2 Microglial Cells. Journal of Biological Chemistry, 285(3), 1616–1626. Available from: https://pubmed.ncbi.nlm.nih.gov/19910459/.
  12. Hunter, D., Oldfield, G., Tich, N., Messenheimer, J. and Sebree, T. 2018. Synthetic transdermal cannabidiol for the treatment of knee pain due to osteoarthritis. Osteoarthritis and Cartilage, 26, p.S26. Available at: https://www.oarsijournal.com/article/S1063-4584(18)30167-5/fulltext [Accessed 7 Nov. 2020].
  13. Blake, D.R., Robson, P., Ho, M., Jubb, R.W. and McCabe, C.S. 2005. Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology, 45(1), 50–52. Available from: https://pubmed.ncbi.nlm.nih.gov/16282192/ .
  14. Shaw, C., Llc, T. and Marcu, J. (n.d.). Cannabidiol in the Management of Comorbid Rheumatoid Arthritis, Lupus, and Raynaud’s Disease. 1(1). Available from: https://www.rebelmd.com/wp-content/uploads/2019/12/AJEM_Shaw_Case-Study.pdf.
  15. Philpott, H.T., OʼBrien, M. and McDougall, J.J. (2017). Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis. PAIN, [online] 158(12), pp.2442–2451. Available from: https://pubmed.ncbi.nlm.nih.gov/28885454/.
  16. Hammell, D.C., Zhang, L.P., Ma, F., Abshire, S.M., McIlwrath, S.L., Stinchcomb, A.L. and Westlund, K.N. 2015. Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis. European Journal of Pain, 20(6), 936–948. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851925/.
  17. Geneva. 2018. CANNABIDIOL (CBD) Critical Review Report Expert Committee on Drug Dependence Fortieth Meeting. Available from: https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf.
  18. Huestis, M.A., Solimini, R., Pichini, S., Pacifici, R., Carlier, J. and Busardò, F.P. 2019. Cannabidiol Adverse Effects and Toxicity. Current Neuropharmacology, 17(10), 974–989. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052834/.
  19. Millar, S.A., Stone, N.L., Yates, A.S. and O’Sullivan, S.E. 2018. A Systematic Review on the Pharmacokinetics of Cannabidiol in Humans. Frontiers in Pharmacology. Available from: https://www.frontiersin.org/articles/10.3389/fphar.2018.01365/full.
  20. Bruni, N., Della Pepa, C., Oliaro-Bosso, S., Pessione, E., Gastaldi, D. and Dosio, F. 2018. Cannabinoid Delivery Systems for Pain and Inflammation Treatment. Molecules, 23(10), p.2478. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222489/.
  21. Lucas, C.J., Galettis, P. and Schneider, J. 2018. The pharmacokinetics and the pharmacodynamics of cannabinoids. British Journal of Clinical Pharmacology, 84(11), 2477–2482. Available from: https://pubmed.ncbi.nlm.nih.gov/30001569/.
Gleb Oleinik, CBD Journalist

Gleb Oleinik is a CBD journalist from Vancouver, Canada with a passion for educating people about the benefits of CBD. He’s read thousands of research studies about CBD and other supplements, helping him translate complex scientific ideas into plain language. When he’s not writing, Gleb likes to spend his time in the gym, out in nature, and working on his website projects.

Interested in trying CBD for arthritis? Here’s our top 10 list of the best CBD oil for arthritis & joint pain in 2021 to help with the issue.