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Best CBD Oil for Pain: The Ultimate Self-Care Guide (2021 Update)

How do you choose the right CBD oil for pain relief?

How do you choose the right CBD oil for pain relief? Royal CBD

Finding the best CBD oil for pain can be time-consuming, not to mention the money and hard work involved with classic trial-and-error. If you want to save both time and money on buying CBD oil, you can use our experience and transfer those resources to one of the three brands we recommend.

Top 4 Best CBD Oil Products for Pain Relief

CBD oil can significantly improve your wellbeing as long as you’re using the right product. Whether you’re dealing with pain, anxiety , or sleeplessness , quality is paramount to your experience.

But how do you choose the right CBD oil for pain relief?

We’ll cover that later in the article, but first, let’s introduce you to some of the best CBD oils we’ve ever tried. Each of these products have been carefully reviewed to make sure you find the best CBD oil for your type of pain.

1. Royal CBD: Best Full Spectrum CBD Oil

Royal CBD

Royal CBD. Royal CBD

Royal CBD oil is made from organic ingredients. The company uses organic hemp plants and supercritical extraction for its products, resulting in pure and potent extracts.

Even its packaging is processed in a sustainable way, so if you value ethical consumerism, then Royal CBD should be high on your list.

When it comes to the quality of Royal CBD oil, “premium” is the right way to describe it.

The oil is suspended in organic MCT oil for improved absorption and additional benefits for the heart and brain from the oil’s essential fatty acids.

Royal CBD oil is available in four strengths: 250 mg, 500 mg, 1000 mg and 2500 mg. You can choose between the natural, citrus and mint flavors.

This is a full-spectrum extract, so you’re getting the entire range of non-psychoactive cannabinoids, as well as trace levels of THC (below 0.3%), terpenes and other compounds from hemp.

2. Gold Bee – Best Organic CBD Oil


Gold Bee. GoldBee

Similar to Royal CBD, Gold Bee specializes in full-spectrum CBD oil from all-organic ingredients. The company combines two superfoods: CBD-rich plants from Colorado and organic honey from Brazilian Rainforest. The Gold Bee CBD oil is a full-spectrum product, so you’re getting the synergistic effects of all cannabinoids and terpenes from the original plant. The maximum potency here is 1200 mg, which translates to 40 mg in each milliliter.

Full-spectrum extracts are generally considered more effective when it comes to easing physical discomfort due to the aforementioned synergy. Suspension in hemp seed oil makes the CBD more available for the body. If you’re not a fan of natural CBD oils, you can try the Kiwi option, which is flavored with honey. Gold Bee also offers high-potency CBD capsules (up to 40 mg per capsule) and delicious honey sticks — a great product selection for a brand with a Bee in its logo.

3. CBDPure – Runner Up


CBDPure is one of the most transparent brands on the market. The company broadly explains every stage of making its CBD oil and has lab reports for each batch of product.

The golden color of the oil is a good indicator of its quality—it means that someone did a good job while filtering the extract from the excess chlorophyll and plant material.

The oil has an earthy scent, which is typical for full-spectrum hemp extracts, but it tastes surprisingly good for one.

It’s not the most potent oil out there. You can choose between three strengths: 100 mg, 300 mg and 600 mg. The lowest potency offers 3.3 mg of CBD per serving, which may be good for very mild pain, or if you’re using CBD oil for the first time.

CBDPure sells both full-spectrum and pure (THC-free) oil. The pure version is better for those who want to benefit from CBD without any THC in their system. Some people just want to err on the side of caution, whereas others can’t use full-spectrum products because they’re subject to regular drug tests at work.

4. NuLeaf Naturals

NuLeaf Naturals

NuLeaf Naturals. NuLeaf Naturals

NuLeaf Naturals has been selling premium CBD oil for over five years now, and surprisingly, the company decided not to extend its line of products.

NuLeaf only sells traditional CBD oil drops—and nothing else.

If you’re looking for a wider product selection, we suggest that you stick with Royal CBD, but if you’re aiming for a full-spectrum CBD oil formulated to perfection, then this company is one of the most reputable manufacturers in the industry.

NuLeaf Naturals offers its CBD oil in five bottle sizes:

  • 5 mL — 240 mg of CBD;
  • 15 mL — 725 mg of CBD;
  • 30 mL — 1450 mg of CBD;
  • 50 mL — 2425 mg of CBD; and
  • 100 mL — 4850 mg of CBD.

The potency of this oil doesn’t change with the bottle’s size, so it’s a good option for people who know their effective dosage and are looking for several months worth of supply.

The only downside about NuLeaf Naturals—aside from the limited product lineup—is that these oils are priced higher than other brands in this ranking while offering similar quality.

What Is CBD Oil?

CBD oil is a natural alternative to over-the-counter supplements—and a modern panacea for a wide range of health concerns. Some people use it to relax and ease their mind after a tense day, whereas others take CBD oil for chronic conditions involving inflammation, pain and poor mood.

CBD is extracted from the flowers of mature cannabis flowers and then processed into an oily extract. The extraction process, as well as the solvents involved, can heavily impact the quality of the end product.

The way CBD produces its effects is still unclear to scientists. However, most experts agree that CBD modulates the endocannabinoid system (ECS), without directly stimulating cannabinoid receptors, in a similar way that THC does.

THC binds to cannabinoid receptors in the brain, mimicking the actions of a similarly built chemical produced by the brain (anandamide), hence the psychoactive effects.

CBD, on the other hand, affects dozens of pathways throughout the human body. It may change the way we experience anxiety, inflammation and pain.

Most Notable Studies on CBD and Pain

CBD oil has a plethora of health benefits, and you can probably name a few right away. It’s considered to be one of the most beneficial cannabinoids in the cannabis plant. Let’s see what studies say about using CBD oil for pain management.

A 2008 review of the existing studies on CBD in relieving chronic pain concluded that CBD was effective in managing pain without causing unwanted reactions.

In 2007, a double-blind controlled study found that CBD can assist patients suffering from neuropathic pain.

Finally, a 2016 study showed positive correlation between the use of CBD and reduced inflammation in arthritis patients. In this study, the researchers applied CBD topical to rats for four consecutive days.

The study concluded that rats who were given CBD showed lower levels of pain and inflammation in the affected areas.

How to Use CBD Oil for Pain

Full-spectrum CBD oil is considered to be the most effective form because it features all compounds that are naturally found in the plant. These include not only cannabinoids, bu also terpenes and essential oils. Studies have found full-spectrum extracts to be more effective at treating pain and inflammation than their single-molecule counterparts.

You can buy CBD oil in a bottle with a dropper. The dropper allows you to measure just the right amount of oil and transfer it under the tongue, where you have to hold it for about 60 seconds before swallowing.

The effects of CBD oil should come within 20 minutes, with benefits lasting for four to six hours, depending on your dosage and metabolism.

There are no strict dosage guidelines to follow when it comes to using CBD oil for pain. That’s because everyone reacts differently to CBD oil.

For starters, we suggest that you determine the severity of pain.

Decide what kind of pain is “manageable” for you, and try to level it down to that point.

For low pain, it’s a good idea to start with 5–10 mg of CBD per day. For medium to high pain, the dosage ranges between 20–100 mg. For more convenient usage, you can also consider choosing high potency CBD edibles .

Why should you go low and slow?

Because some people are very sensitive to cannabis compounds. There are individuals who benefit from ridiculously low doses. Lower increments allow for more accurate dosing, making sure you won’t experience any side effects aside from its benefits.

CBD Oil or CBD Cream: Which One Should I Use for Pain?

Having pain on your leg may lead you to think that applying CBD cream on the affected area will yield better results than swallowing CBD oil.

Well, this isn’t actually the case.

Using CBD topicals on painful areas is a good option if the pain is shallow. Using CBD topicals on painful areas is a good option if the pain is shallow. CBD topical creams only work on anatomical structures that are located up to one-centimeter under the skin.

And when you struggle with joint inflammation or muscle soreness, the problem is probably more complex than that.

CBD topicals generally call for a liberal splash over the affected area. If you have a generous hand with creams, there’s a chance that some of it will penetrate the skin down to your muscles.

It doesn’t mean that you shouldn’t use topicals at all. In fact, they make for a great addition to CBD oil because they approach the problem from a slightly different angle.

How to Determine a High Quality CBD Oil

If you’re trying a new product for your well-being or symptoms for the first time, you want to make sure it’s the highest quality possible.

Here are the most important buying criteria:

The Source

The source of CBD is paramount to the quality of the end product. Hemp plants are bioaccumulators, meaning they absorb every substance from the soil they were planted in—including both the bad and the good substances.

When grown in fertile soil, without using pesticides and other toxic chemicals, hemp will be high in CBD and nutrients. It will also be free of contaminants. That’s why it’s important to choose companies that make their products from organic hemp.


This is the second-most important factor to consider when buying CBD oil for pain. Potency tells you how much CBD there is in the bottle, as well as in each milliliter of the oil.

Look for brands that sell CBD oil in a wide range of concentrations. That way, you’ll be able to choose the most efficient option, both in terms of the effects and your budget.

Please remember that higher potency doesn’t mean the oil will work better for you. As noted, some people benefit from low doses, so if a 250 mg bottle does the trick for your pain, there’s no need to look for stronger options.

Extraction Method

Extraction means pulling CBD and other compounds from the plant material using some kind of solvent. The golden standard for making CBD products is CO2 extraction.

CO2 is used as a solvent that changes its state from gas to liquid, penetrating the plant and extracting cannabinoids from it. Eventually, the CO2 will dissipate, leaving behind an oily, viscous extract.

Alternative extraction methods include olive oil or alcohol (tinctures). Steer clear of CBD oil that was made with butane, as this solvent is difficult to work with and may leave toxic residue at the bottom of your oil if handled improperly.

Third-Party Testing

CBD companies can send samples of their products for content analysis to independent laboratories.

These laboratories check the potency of CBD and look for common contaminants in the end products. Before CBD oil makes it on the shelves, the company should ensure that there are no inconsistencies in the CBD concentration and purity levels.

Third-party testing is the only way to confirm that you’re getting exactly what you’re buying. Most reputable companies display lab reports on their websites.

Where to Buy CBD Oil

It’s quite easy to find CBD oil for sale these days because the market is growing and new CBD companies are popping up each month. You can either get your CBD oil online or buy it from one of the local dispensaries in your state.

We don’t recommend head shops, food stores or other brick-and-mortar stores, as they usually carry overpriced products whose quality leaves a lot to be desired.

Buying CBD oil online gives you access to a wider range of products, attractive seasonal deals and other perks for registered customers

You can easily verify the credibility of your potential vendor by simply reading how they manufacture their products, checking the Certificates of Analysis, or looking at reviews from other customers and ratings at CBD-dedicated websites.

Potential Side Effects of CBD Oil

Your safety should be your top priority, so it’s important that you understand the possible risk of taking CBD oil.

The good thing is that CBD oil doesn’t really have serious side effects. The World Health Organization has acknowledged it as a safe product that doesn’t cause dependency.

The most common reaction to CBD oil is the sensation of dryness in the mouth. This is typical to all cannabis products and results from the effect of cannabinoids on salivation. You can avoid this side effect by staying well hydrated after applying CBD oil.

Experiencing dizziness due to lowered blood pressure is also common among CBD users. At extremely high doses, CBD can cause diarrhea and nausea. It happens when you take more than your body can handle, so you simply flush the excess oil out of your system.

Having a dry mouth can also temporarily suppress your appetite, but these effects should pass over time.

Last but not least, there are a couple of medications that can negatively interact with CBD.

For example, CBD is a blood-thinning agent. By lowering your blood pressure, CBD oil can result in harmful levels of hypotension.

If you take any prescription drugs, it’s best to consult with a doctor prior to buying any CBD product.

Final Thoughts on Using CBD Oil for Pain

CBD oil comes with a myriad of health benefits, including relief from different types and levels of pain. The lion’s share of these benefits result from CBD’s interaction with our endocannabinoid system.

By altering pain transmission from nerves to the brain, CBD can help people manage pain and improve their quality of life in a safe and natural way. However, it’s important that you only use high-quality products that come from reputable manufacturers. Only then will you be able to get the most out of CBD’s analgesic properties.

Best CBD Oil for Pain: The Ultimate Self-Care Guide (2021 Update)

We hope that this guide has helped you get a better understanding of CBD products. Feel free to use our recommendations and let us know how CBD oil helped you with your pain!

What’s the best CBD oil for dealing with different types of pain? How does using CBD oil for pain compare to traditional remedies? Find these out and more in our ultimate buying guide.

CBD for Nerve Pain

CBD for Nerve Pain

Pain: An Overview

Let’s face it: No one deals with pain very well. Some may handle it better than others, but pain can limit your enjoyment and quality of life. Can CBD be a tool to help you to fight pain? Let’s see what the science says.

Pain—the sensation of discomfort that results from some form of illness, injury, or stimuli—is the body’s way of communicating that something is wrong.

Pain is classified in several ways: it can be acute (sudden and temporary) or chronic (long-lasting); it can be sharp or dull, and it can sting, burn, throb, ache, or feel like pressure.

Pain can also be constant or it can come and go. Pain is very subjective; one person may complain that they are in agony while another may shrug off a similar pain experience.

Pain can also be classified by cause:

  • Nociceptive pain is caused by damage to tissue. This can be caused by injury, inflammation, lack of oxygen and/or specific diseases like cancer or arthritis.
  • Neuropathic pain is caused by damage to the nerves that transmit the signal from the injured area to the brain. Neuropathic pain can also be caused by injury, inflammation, lack of oxygen and/or a specific disease, but it can also be caused by medication or a stroke, or even infections like HIV or bacterial infections.

Neuropathic or nerve pain tends to feel like a burning or prickling—a sense of “pins and needles.” Often, people with neuropathic pain may be hypersensitive to movement, temperature, and touch.

Some common types of nerve pain include:

  • Central Pain Syndrome (CPS): CPS-related pain arises from damage to the central nervous system (CNS)—the brain and spinal cord. The pain is most commonly the result of a stroke or a CNS-related disease such as multiple sclerosis.
  • Complex Regional Pain Syndrome (CRPS): CRPS-related pain is the result of a serious injury and is described as a severe burning sensation.
  • Diabetic peripheral neuropathy is caused by damage to the nerves of the hands, feet, legs, or arms. This damage has a number of likely causes:
    • Chronically high blood sugar levels are believed to act as a toxin.
    • Blood flow to an area of the body can decrease and become hypoxic or oxygen starved.
    • High blood pressure and low levels of HDL cholesterol coupled with high levels of LDL and triglycerides increase the risk of peripheral neuropathy found in people with diabetes.
    • Obesity and smoking can increase the risk of peripheral neuropathy.
    • Oxidative stress, in which highly reactive molecules, known as free radicals, can damage cellular structures—especially the mitochondria, known as the “powerhouse of the cell.”
  • Myofascial Pain Syndrome is pain caused by inflammation of the soft tissue and muscles. It may be pain that is localized to a single muscle or a group of muscles. It can be caused by repetitive motion, injury, some medical conditions, strain, or non-use/under-use of a muscle or muscle group.
  • Shingles, also known as postherpetic neuralgia, is caused by the same virus that causes chickenpox (varicella-zoster, for the curious, is a type of herpesvirus). If you have ever had chickenpox, the virus can settle into nerve cells and lay dormant for years. Then—possibly due to stress, medications, and/or age—the dormant (latent) virus suddenly starts replicating, and a rash appears. The rash itself is quite painful and consists of reddened skin covered with fluid-filled blisters along a single band or stripe somewhere on the body. The pain is often described as burning, numbing, or tingling.
  • Trigeminal neuralgia is an inflammation of the trigeminal nerve, a facial nerve that controls biting, chewing, smiling, and other facial movements. It also controls sensation in the face. Trigeminal neuralgia pain is described as a shooting or jabbing pain that runs along the jaws and cheeks. Usually, this happens on one side of the face. It can be caused by pressure on the nerve, a disease like multiple sclerosis, a tumor, or another neurologic disorder.
  • Referred pain, or reflective pain, is described as pain felt in a location other than where the actual damage is. The pain some people experience along the left (or right) arm, jaw, or teeth during a heart attack is a well-known example of referred pain.

CBD and Nerve Pain Relief

Animal Studies

Since pain is a subjective experience, it can be difficult to quantify CBD’s effect on pain relief. Research into pain offers conflicting results. One recent study noted these differences, stating that in animal studies, cannabinoids reduced pain in several different models of pain, while in human studies, the results were less conclusive.

Topical CBD was able to reduce inflammation and pain caused by arthritis, a recent study reported.

One potentially important study showed that CBD may reduce chronic inflammatory and neuropathic pain without users developing a tolerance for it. Tolerance is the phenomenon wherein someone using a particular drug over time stops experiencing its effectiveness at that dose.

Human Studies on CBD for Nerve Pain

There are still relatively few human studies available—and even fewer studies using CBD alone. Most of the studies use cannabis-derived combinations of THC (tetrahydrocannabinol, the cannabinoid which produces a “high”), CBD, and synthetic cannabinoids.

  • One study looked at chemotherapy-induced neuropathic pain and found that CBD was safe and able to reduce this type of pain.
  • A recent analysis of 11 different studies concluded that CBD and other cannabinoids may provide some pain relief in neuropathic pain.
  • Another review of medical cannabis for pain experienced by cancer patients stated, “There is evidence suggesting that medical cannabis reduces chronic or neuropathic pain in advanced cancer patients.”
  • CBD was also found to be effective in reducing muscle spasms and pain associated with patients suffering from multiple sclerosis.

All the studies indicate that CBD has an excellent safety profile and few side effects (which typically include nausea and diarrhea).

Summary of CBD for Nerve Pain

We are currently stuck in a catch-22 with CBD: It is still relatively rare for researchers to study CBD alone and its effects on pain or its effects on anything else. Medical studies are often difficult to set up—and for CBD studies to have any impact or carry any clout, they need to be better designed, better controlled and larger that are currently available in CBD research. Yet, most of the people who are currently using CBD to achieve pain relief would likely be excluded (for valid reasons of scientific bias) from these very studies.

Also, people in pain are often less interested in clinical trials—they’ve tried a lot of different approaches and often would rather be talking about getting real pain relief than “oh, let’s try this—it may work”. They often know that in clinical trials, they may be randomized into the “placebo” group, and may not want to deal with a potentially worse situation. As a result, it is often to get people in specific groups to sign up for clinical trials.

CBD has been validated as an anti-inflammatory agent in several studies—it also has neuroprotective properties. Inflammation is a common factor in the progression of pain, so it is reasonable to think that the anti-inflammatory properties in CBD could reduce pain just as other anti-inflammatory agents in other pain relievers do, such as NSAIDs like aspirin and analgesics such as Tylenol.

Anecdotal evidence has supported the efficacy of cannabis and cannabis-derived products for thousands of years. That may not be a gold standard approach in modern medicine, but people have been using this approach for thousands of years.

The upshot is that the world may have to wait for the science to catch up. The maxim of “start low and go slow” is the likely best approach when and if you decide to try CBD for nerve pain—start at a low dose and increase it slowly until you get the desired relief. Depending on the area of pain, topical CBD is likely your best choice—start with a pea-sized amount of topical and slowly increase it.

If you have widespread pain, using CBD oil drops could be a good approach: Start with one drop by mouth (under the tongue may work better for some) and slowly increasing it—trying it for at least two to three days at the same dose to see if it’s working. It is best used “neat” or undiluted, but if you need to, you can add it to some water or an herbal tea, though you should avoid using coffee, soda or black/green tea to wash it down. Alternatively, if the pain is in a smaller area, you can apply the oil directly onto the painful area, rubbing it in. Again, start with one drop and wait 15-20 minutes and add more as needed, one drop at a time.

CBD for Nerve Pain Pain: An Overview Let’s face it: No one deals with pain very well. Some may handle it better than others, but pain can limit your enjoyment and quality of life. Can CBD